Abstract. Transposable elements (TEs) comprise nearly half of mammalian genomes and drive species-specific regulatory innovation, but their contributions t

Abstract. Epigenetic regulation of chromatin structure is strongly influenced by histone variants and post-translational modifications. The conserved histo

We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog

The maternal-to-zygotic transition (MZT) marks a fundamental shift in embryonic control from maternally supplied factors to zygotic gene activation, a process critical for vertebrate development. Cont...

Podcast Episode · Epigenetics Podcast · February 26 · 39m

Meiotic recombination generates crossovers (COs), reciprocal exchanges between homologous chromosomes critical for accurate chromosome segregation. Inappropriate CO frequency and distribution drive an...

Looking for your first postdoctoral position can be confusing but being proactive, and focusing on your research interests and career goals can help. This useful post from a recent postdoctoral fellow...

Pioneer transcription factors are crucial for regulating zygotic genome activation and cell differentiation during mouse pre-implantation development. However, how pioneer factors function collectivel...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome.

Craniofacial Developmental Protein 1 (CFDP1) is a member of the evolutionarily conserved family of Bucentaur (BCNT) proteins and was originally classified as a protein required for cell survival and d...

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New in situ chromatin profiling methods, such as CUT&Tag, have streamlined studies of chromatin features by eliminating the need for up-front purification, but we find that some features are not equal...

Meng et al. develop a method called TransTag for simple and efficient mapping of Tol2-based transgenes in zebrafish. TransTag robustly identifies transgene insertion sites and offers an alignment-free...

Meng et al. develop a method called TransTag for simple and efficient mapping of Tol2-based transgenes in zebrafish. TransTag robustly identifies transgene insertion sites and offers an alignment-free...