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Pierpaolo Sorrentino

@pierpasorre.bsky.social
180 followers 348 following 2 posts

I am a Neurologist and an Engineer, mainly using systems neuroscience applied to Neurological diseases. I am a tenured Associate Professor, working at Aix-Marseille university & Sassari university.

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Reposted by Pierpaolo Sorrentino
Bratislav Misic @misicbata.bsky.social · 25/09/2026
Spatial organization of AQP4 water channel expression in the human brain | doi.org/10.1126/scia... Aquaporins are a key component of the glymphatic system. How are they distributed + how do they relate to brain function and dysfunction? ⤵️
doi.org
Spatial organization of AQP4 water channel expression in the human brain
Aquaporin-4 (AQP4) water channels support the glymphatic system, a brain-wide pathway that clears cerebral waste products. Here, we use AQP4 gene expression to reconstruct a whole-brain glymphatic-rel...
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Thomas Yeo @bttyeo.bsky.social · 13/06/2026
Openly shared implementation of TMS targeting is still rare, so we are pleased to make ours freely available for research use: github.com/ThomasYeoLab... Let us know if you have any issue running it!
github.com
GitHub - ThomasYeoLab/Kong2026_TMSTree: Tree-based MS-HBM TMS targeting algorithm
Tree-based MS-HBM TMS targeting algorithm. Contribute to ThomasYeoLab/Kong2026_TMSTree development by creating an account on GitHub.
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Marie-Constance Corsi @mconstancecorsi.bsky.social · 17/04/2026
[5/5] 📍 Attending the NCM annual meeting next week? Come discuss with Camilla Mannino! 🗓️ Poster P1-E-120 — April 21 & 22 Many thanks to: @pierpasorre.bsky.social, Marianna Angiolelli, Matteo Demuru, Francesca Trojsi & Mario Chavez!
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Pierpaolo Sorrentino @pierpasorre.bsky.social · 09/03/2026
🧠 Real-world diagnosis ≠ case vs controls! Can MEG distinguish multiple diseases at once? Turns out a small set of phase-based connectivity edges can separate #MS, #ALS, #PD, and #MCI! @mconstancecorsi.bsky.social @inserm.fr @univ-amu.fr @univparissaclay.bsky.social 🔗 doi.org/10.1016/j.he...
doi.org
Redirecting
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Micah G. Allen @micahgallen.com · 05/03/2026
In case you missed it, I made a feed that uses a locally hosted LLM to sort through the entire Bluesky firehose to find great science. Topics span all cognitive science and neuroscience. Check it out! bsky.app/profile/did:...
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Brigit Strawbridge @brigitstrawbridge.bsky.social · 20/02/2026
🤎
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Bruce Springsteen @brucespringsteen.net · 28/01/2026
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free
youtu.be
Bruce Springsteen - Streets Of Minneapolis (Official Audio)
YouTube video by Bruce Springsteen
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Terre-Strial @terre-strial.bsky.social · 23/12/2025
“The longer I live, the more convinced I am that this planet is used by other planets as a lunatic asylum.” - George Bernard Shaw
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Mark Rubin @markrubin.bsky.social · 19/12/2025
"How can funders avoid crossing the Szilard point?" The Szilard point is "the threshold at which the total cost of competing for a grant equals (or surpasses) the value of the available funding."
nature.com
Point of no returns: researchers are crossing a threshold in the fight for funding
With so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.
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Giovanni Rabuffo @grabuffo.bsky.social · 17/12/2025
New preprint out! How does criticality propagate from local neuronal circuits to whole-brain dynamics? We tackle this with a multiscale, connectome-based mouse model @ldallap.bsky.social . 🧵/n 👉 biorxiv.org/content/10.6...
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Giovanni Rabuffo @grabuffo.bsky.social · 17/12/2025
Big thanks to the solid team @ldallap.bsky.social, @pierpasorre.bsky.social, @mnpompili.bsky.social, Pietro Bozzo, Bach Nguyen, Tomoki Fukai, Damien Depannemaecker, Leonardo Gollo
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Paolo Enrico @p-enrico.bsky.social · 05/12/2025
We started this research project almost for fun, and now it's a preprint!!! ssrn.com/abstract=585... #neuroscience #neuroskyence
ssrn.com
Neural Encoding of Symbolic, Non-Symbolic, and Embodied Non-Symbolic Numerical Information in Young and Older Adults
Numeracy has important implications across the lifespan, and age-related decline represents a vulnerability for older adults managing daily tasks, yet underlyin
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Earl K. Miller @earlkmiller.bsky.social · 22/11/2025
Time, space, memory and brain–body rhythms www.nature.com/articles/s41... #neuroscience
nature.com
Time, space, memory and brain–body rhythms - Nature Reviews Neuroscience
Understanding how the brain represents experienced time and how representations of space and time are integrated to form episodic memories has been a goal of much neuroscientific research. In this Per...
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Rick Betzel @richardfbetzel.bsky.social · 18/11/2025
Stop by this afternoon to chat about community structure in the 🪰connectome! 📍ZZ2/PSTR368.03
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Giovanni Rabuffo @grabuffo.bsky.social · 22/09/2025
With deep gratitude to my extraordinary co-authors @MariannaAngiolelli, @FukaiTomoki, @GustavoDeco, @pierpasorre.bsky.social, and @davemomi.bsky.social —this work would not have been possible without them. Supported by the MSCA grant @ec.europa.eu and @upf.edu—more to come!
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Marie-Constance Corsi @mconstancecorsi.bsky.social · 05/09/2025
🧠 Join us for the Brain Models for Multimodal Integration Symposium! 📅 12 September 2025 | ⏰ 12:00–13:15 UTC | 🌐 Virtual Event Thrilled to co-chair w/ @pierpasorre.bsky.social at the @ohbmofficial.bsky.social Satellite Meeting! Feat. D. Depannemaecker & @gianmarcoduma.bsky.social ma.bsky.social.
https://ohbm-environment.org/ohbm-satellite-event/
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Imaging Neuroscience @imagingneurosci.bsky.social · 05/09/2025
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date. We're very happy to announce that we are able to reduce the APC to $1400. Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
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Marie-Constance Corsi @mconstancecorsi.bsky.social · 27/08/2025
📢 Preprint alert! 🧠💡 Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs 🔗 www.biorxiv.org/content/10.1... A great work led by Camilla Mannino w/ @pierpasorre.bsky.social & @neurodynamicslab.bsky.social! @nerv-lab.bsky.social @institutducerveau.bsky.social 🧵
biorxiv.org
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
Motor imagery-based Brain-Computer Interfaces (BCIs) restore control in persons with motor impairments, but up to 30% of users struggle—a phenomenon known as “BCI inefficiency”. This study tackles a k...
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camille-mazzara.bsky.social @camille-mazzara.bsky.social · 23/07/2025
🧠 New Preprint out! Brain fluidity: a functional marker of neuronal death in Alzheimer’s disease (AD). Our results highlight the link between dynamic brain connectivity disruptions and neurodegeneration in AD. @pierpasorre.bsky.social @gianmarcoduma.bsky.social www.medrxiv.org/content/10.1...
medrxiv.org
Brain Fluidity as a Functional Marker of Tau-Related Neurodegeneration in Alzheimer’s Disease
Alzheimer’s Disease (AD) is the most common form of dementia and one of the leading neurodegenerative disorders worldwide. Neurophysiopathologically, AD is characterized by neuronal death, accompanied...
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Decision, Action, and Neural Computation (DANC) lab @danclab.bsky.social · 23/07/2025
Beta burst waveforms in PD! We find that specific types of beta bursts are rate-modulated by l-dopa, and STN-cortical connectivity during these burst types is related to clinical improvement. Fantastic work by Hasnae Agouram with @pierpasorre.bsky.social 🧠📈
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Le Neuro (Institut-Hôpital neurologique de Montréal) @theneuro.bsky.social · 15/07/2025
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
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Sonica Saraf @sonicasaraf.bsky.social · 29/06/2025
In many brain areas, neuronal tuning is heterogeneous. But how does this diversity help behavior? We show how tuning diversity shapes representational geometry and boosts coding efficiency for perception in our new preprint: www.biorxiv.org/content/10.1... (w/ @sueyeonchung.bsky.social&Tony Movshon)
biorxiv.org
Variations in neuronal selectivity create efficient representational geometries for perception
Our visual capabilities depend on neural response properties in visual areas of our brains. Neurons exhibit a wide variety of selective response properties, but the reasons for this diversity are unkn...
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Andrea Santoro @andreasantoro.bsky.social · 27/06/2025
🧠 Want to understand how different higher-order methods compare in brain connectivity analysis? Check out our new preprint — a fantastic collab with past & present NPL members @lordgrilo.bsky.social : 🔗 www.biorxiv.org/content/10.1... A thread🧵
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BCI Society @bcisociety.bsky.social · 06/05/2025
Congratulations to Marie-Constance Corsi recipient of this year’s Early Career Award! Dr. Corsi’s innovative work in the #BCI field is already making a big impact.
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EBRAINS @ebrains.bsky.social · 27/05/2025
A new computer model of Parkinson's disease has been created by researchers in France and Italy and tested in a first small-scale patient trial. Read more: www.ebrains.eu/news-and-eve...
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Laura Dugué @lauradugue.bsky.social · 02/05/2025
Researchers in France are working on creating a french network of researchers to organize interaction, communication and training in #Computational_Neuroscience. If you are a CompNeuro working in France, consider joining, and registering to our mailing list: listes.services.cnrs.fr/wws/subscrib...
listes.services.cnrs.fr
rt_neurocomp - réseau français de neurosciences computationnelles - subscribe
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Simon Eickhoff @sbe.bsky.social · 24/04/2025
Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus jamanetwork.com/journals/jam...
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PessoaBrain @pessoabrain.bsky.social · 21/04/2025
How do local brain perturbations affect global processes? doi.org/10.1073/pnas... #neuroscience
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Giovanni Rabuffo @grabuffo.bsky.social · 19/04/2025
After a long journey, our paper is officially out in PNAS! 🚀 Huge thanks to the team — excited to finally share it with the world. Check it out: www.pnas.org/doi/10.1073/...
pnas.org
Mapping global brain reconfigurations following local targeted manipulations | PNAS
Understanding how localized brain interventions influence whole-brain dynamics is essential for deciphering neural function and designing therapeut...
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Rick Betzel @richardfbetzel.bsky.social · 11/04/2025
sometimes this is what neuroimaging feels like: www.science.org/doi/abs/10.1...
science.org
Chaos in the Brickyard
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Gaël Varoquaux @gaelvaroquaux.bsky.social · 22/03/2025
Open source is draining. One's todo-list is open to world. People seldom realize the cost of what they get for free. Unpleasant comments do happen. Cost of maintenance is not understood. opensource.com/article/17/2...
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Adeel Razi @adeelrazi.bsky.social · 17/03/2025
🧵 How do psychedelics shape brain activity? Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states. Title: Psychedelics Align Brain Activity with Context Paper: lnkd.in/gt-kMR6d A thread 🧵👇 1/n
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Oded Rechavi @odedrechavi.bsky.social · 14/03/2025
137 scientists from around the globe already signed up, what are you waiting for?
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Randy McIntosh @ar0mcintosh.bsky.social · 13/03/2025
This is a bright spot to start the day (on the West Coast, that is). The paper on "possibility space" with @laurennross.bsky.social and Viktor Jirsa is now published! onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
The Possibility Space Concept in Neuroscience: Possibilities, Constraints, and Explanations
Although the brain is often characterized as a complex system, theoretical and philosophical frameworks often struggle to capture this. For example, mainstream mechanistic accounts model neural syste...
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Tiago Peixoto @tiago.skewed.de · 12/03/2025
🚨 New paper on ArXiv: “Uncertainty quantification and posterior sampling for network reconstruction” TL;DR; We present an efficient method to sample the entire ensemble of possible network reconstructions that are compatible with an indirect observation, e.g. a dynamics. Short thread: 1/N
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Bratislav Misic @misicbata.bsky.social · 11/03/2025
Cerebral blood perfusion across biological systems and the human lifespan | doi.org/10.1101/2025... How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️
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Marie-Constance Corsi @mconstancecorsi.bsky.social · 10/03/2025
🚨 Preprint Alert 📝 🚨 Artificial Intelligence for automatic movement recognition: a network-based approach! 🔗 www.biorxiv.org/content/10.1... A great collaboration with notably Emahnuel Troisi-Lopez & @pierpasorre.bsky.social! 🧵
biorxiv.org
Artificial Intelligence for automatic movement recognition: a network-based approach
Introduction automatic movement recognition is often used to support various fields such as clinical, sports, and security. To date, there is a lack of a classification feature that is both interpreta...
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Masud Husain @masudhusain.bsky.social · 06/03/2025
Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness academic.oup.com/brain/articl...
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PessoaBrain @pessoabrain.bsky.social · 06/03/2025
Groundbreaking work by Dr. Soohyun Lee from the National Institute of Mental Health at NIH The brilliant young scientist faces termination. Science like this leads to discoveries that can revolutionize how we understand the brain. doi.org/10.1038/s415... #neuroscience #neuroskyence
doi.org
Brain-wide presynaptic networks of functionally distinct cortical neurons - Nature
Behavioural-state-dependent pyramidal neurons have a distinct pattern of long-range glutamatergic inputs, with a larger proportion of thalamic versus motor cortex inputs compared with non-behavio...
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Marc L Seal @parkvillegeek.bsky.social · 04/03/2025
How to communicate the value of curiosity-driven research | The Transmitter: Neuroscience News and Perspectives www.thetransmitter.org/outreach/how...
thetransmitter.org
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Jarod Levy @jarodlevy.bsky.social · 26/02/2025
🔥”Brain-to-Text Decoding” is now out on ArXiv: arxiv.org/abs/2502.17480 Our paper from AI at Meta and @bcbl.bsky.social presents Brain2Qwerty, an AI model that decodes text from non-invasive recordings of the brain. Below a detailed thread 🧵1/7
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The Transmitter @thetransmitter.bsky.social · 24/02/2025
Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments towards deeper insights, writes @gershbrain.bsky.social. #neuroskyence www.thetransmitter.org/theoretical-...
thetransmitter.org
Breaking the barrier between theorists and experimentalists
Many neuroscience students are steeped in an experiment-first style of thinking. Let’s not forget how theory can guide experiments.
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Andrew Zalesky @andrewzalesky.bsky.social · 25/02/2025
The brain-heart connection: Shared Pathways of Brain and Cardiovascular Health medicalxpress.com/news/2025-02... www.jneurosci.org/content/45/8...
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davemomi.bsky.social @davemomi.bsky.social · 24/02/2025
🚀 @GiovanniRabuffo is presenting our poster "Large-Scale Neural Dynamics as a Predictor of Stimulus Effects" at the 6th #BrainStimConf! 📍 Poster P2.064 Don't miss it—come discuss our latest findings on neural dynamics and stimulation effects! #BrainStimulation #Neuroscience
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George O’Neill @goneill.bsky.social · 18/02/2025
HOT OFF THE PRESS - Back in 2019 we started asking ourselves what could you to demonstrate where werable, OPM-MEG technology could fit into naturalistic #neuroskyence. One snag, we'd have to build the system from scratch first... Anyway its 2025, read the paper here -> doi.org/10.1162/imag...
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Andrew Zalesky @andrewzalesky.bsky.social · 13/02/2025
TMS is delivered to the DLPFC in depression to modulate SGC activity But axons linking DLPFC and SGC are absent. How then does TMS stimulation delivered to the DLPFC modulate SGC activity? Check out Caio's work on how stimulation effects propagate in the absence of direct anatomical paths
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Randy McIntosh @ar0mcintosh.bsky.social · 06/02/2025
Many of these atlases are relevant for modern work and are beautiful examples of science and art. If you have a chance to check them out, it's astounding - considering it was done late 1800's to 1940-ish Here's a cool one from ~1859! /fin museumsandcollections.unimelb.edu.au/__data/asset...
museumsandcollections.unimelb.edu.au
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Alessandro Gozzi @gozziale.bsky.social · 31/01/2025
TransBrain: A computational framework for translating brain-wide phenotypes between humans and mice www.biorxiv.org/content/10.1...
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Ben Fulcher @bendfulcher.bsky.social · 29/01/2025
Full PhD scholarship + stipend (for an Australian or international student) to join our group and study the nonlinear dynamics of sleep (or related topics in time-series analysis of complex dynamical systems). Apply here (via Project 7): www.sydney.edu.au/scholarships...
sydney.edu.au
ARC Postgraduate Research Scholarship
A $40,109 per annum stipend scholarship for research students within the Faculty of Science.
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Pierpaolo Sorrentino @pierpasorre.bsky.social · 22/01/2025
Looking for a home for cross-disciplinary work? @parulv.bsky.social and I are hosting on Nature NPJ: combining theory and neurotechnology for a multiscale account of the brain. We aim to create space for lateral thinking and visibility for new solutions! nature.com/npjsba/for-a...
nature.com
For Authors and Referees | npj Systems Biology and Applications
For Authors and Referees
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