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Abstract. Candida auris is an emerging fungal pathogen causing invasive infections in immunocompromised patients, with mortality rates reaching up to 60%.

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Candida auris, an emerging multidrug-resistant fungal pathogen, preferentially colonizes human skin, leading to outbreaks of systemic infections. A re…

Candida auris, an emerging multidrug-resistant fungal pathogen, preferentially colonizes human skin, leading to outbreaks of systemic infections. A recent study by Phan-Canh et al. characterized CO2-sensing pathways in C. auris, which regulate amphotericin B susceptibility and skin colonization.

A new study involving the Medical University of Vienna shows how the multi-resistant fungus Candida auris utilizes carbon dioxide (CO₂) to survive on the skin and become resistant to antifungal therapies.

Candida auris can scavenge carbon dioxide from microenvironments through Nce103 to sustain fitness when colonizing human skin.

Nature Microbiology - Candida auris can scavenge carbon dioxide from microenvironments through Nce103 to sustain fitness when colonizing human skin.

Hospital-acquired fungal infections, which pose a serious risk to immunocompromised patients, are a growing global health challenge. In a new study published in Cell Reports, first author Trinh Phan-C...

Using transcriptomics and reverse genetics, Phan-Canh et al. present a comprehensive analysis of genes governing phenotypic White-Brown switching in the multidrug-resistant fungal pathogen Candida auris. White and Brown morphotypes exhibit distinct stress responses and virulence traits, linked to complex gene regulatory networks that govern the phenotypic plasticity during fungal infections.

Using transcriptomics and reverse genetics, Phan-Canh et al. present a comprehensive analysis of genes governing phenotypic White-Brown switching in the multidrug-resistant fungal pathogen Candida aur...

AlphaFold’s highly accurate structural models transformed protein biology,but RNA lags behind.

Candida auris is a human fungal pathogen of utmost medical relevance exhibiting exceptionally high resistance to all clinically used antifungal drugs, including azoles, polyenes, and echinocandins as ...

DNA hypomethylation in human tumor cells results in the activation of the LINE-1-derived RNA-binding protein L1TD1 and its interactions with LINE-1 transposons.