Reposted by Mark GresnigtAmelia Barber @ameliabarberphd.bsky.social · 29/07/2025My group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share! More info and applications at @ jobs.uni-jena.de/vrbup 14847
Reposted by Mark GresnigtLeibniz-HKI @leibniz-hki.de · 22/07/2025💡 New infection strategy in #Candida albicans discovered: human #albumin reprograms its metabolism, turning harmless strains pathogenic – without the need of hyphae or toxins. #LeibnizHKI 🗞️ lmy.de/mthFi 🧪 rdcu.be/exl7d @markgresnigt.bsky.social @aps-hki.bsky.social @dfg.de @microverse.bsky.social 1113
Reposted by Mark GresnigtAdaptive Pathogenicity Strategies @aps-hki.bsky.social · 14/07/2025We are exited to share our story just out in @natcomms.nature.com on how the yeast Candida albicans can exploit human albumin to engage an alternative pathogenicity pathway, not relying on previously uncovered virulence factors. www.nature.com/articles/s41...nature.comHost albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway - Nature CommunicationsCandida albicans normally relies on specific pathogenicity mechanisms to cause tissue damage. This study reveals that when sensing host albumin, C. albicans, even avirulent strains, can trigger an alt... 0135
Reposted by Mark GresnigtMicrobial Pathogenicity Mechanisms @mpm-hki.bsky.social · 12/05/2025Our newest review is published in @femsjournals.bsky.social! Marisa Valentine discusses the host-pathogen-microbiome interactions during #vaginal #Candida infections.🍄🧫🦠 Big thank you to Duncan Wilson and @markgresnigt.bsky.social for contributing! 👉 academic.oup.com/femsre/advan... 185
Reposted by Mark Gresnigttrr124-funginet.bsky.social @trr124-funginet.bsky.social · 31/03/2025What an incredible joint meeting „FungiNet – Pathogenic fungiand their human host“ & „Invasive Mycoses in Haematological Malignancies – IMIHM XV in Würzburg! 🌟 The discussions were enlightening, and the talks were truly inspiring. 🙌 A big thank you to everyone involved! 094
Reposted by Mark GresnigtSlavica Janevska @slavi-jan.bsky.social · 01/04/2025The meeting ended with an exciting panel discussion on possible future directions after 12 glorious years of the @dfg.de funded @trr124-funginet.bsky.social consortium. With @estukenbrock.bsky.social, Oliver Kurzai, Axel Brakhage and others. 182
Reposted by Mark GresnigtIlan Schwartz @germhuntermd.bsky.social · 01/04/2025Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books Isabela Rost / Alessandro Pasqualotto and colleagues academic.oup.com/ofid/article...academic.oup.comCracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical BooksAbstract. Textbooks remain a primary source of reference and education for many health care professionals and students. This study assessed the mycology co 2128
Reposted by Mark GresnigtScheu Lab @scheu-immuno-lab.bsky.social · 25/03/2025Fascinating evening🌇keynote given by David @sancholab.bsky.social on how the gut microbiome trains the immune system inside the bone marrow🦴 and how its metabolites impact atherosclerosis 👏🏻 021
Reposted by Mark GresnigtScheu Lab @scheu-immuno-lab.bsky.social · 25/03/2025And keynote speaker of day 2 Karsten Hiller of @tubraunschweig.bsky.social is giving us a deep dive into immuno metabolism in macrophages: #itaconate rules ✌🏻🤓 #Rothenfels2025 042
Reposted by Mark GresnigtAdaptive Pathogenicity Strategies @aps-hki.bsky.social · 26/03/2025We are incredibly proud of Kar On Cheng for winning the best presentation award at the 28th Symposium: "Infection and Immune Defense". She presented her doctorate project on IL-36 and its role in inflammation during RVVC. Congratulations Kar On!!! 053
Mark Gresnigt @markgresnigt.bsky.social · 19/03/2025My group @aps-hki.bsky.social is looking for a new postdoc in immunology of fungal infections focusing on vulvovaginal candidiasis. Please contact me for further details in case of interest. 035
Reposted by Mark GresnigtFEMS Journals @femsjournals.bsky.social · 16/01/2025Pathogenic microorganisms employ adaptive strategies to escape host defense. Hitzler et al. explore how bacterial and fungal pathogens escape the host immune system. buff.ly/4ajQ9On #FEMSMicrobiolRev @markgresnigt.bsky.social 075
Mark Gresnigt @markgresnigt.bsky.social · 23/01/2025Proud to share our latest article with the group of Mihai Netea showing that lactic acid in the vaginal milieu modulates the Candida-host interactions that underlie the immune responses associated with vulvovaginal candidiasis www.tandfonline.com/doi/full/10....tandfonline.comLactic acid in the vaginal milieu modulates the Candida-host interactionVulvovaginal candidiasis (VVC) is one of the most common infections caused by Candida albicans. VVC is characterized by an inadequate hyperinflammatory response and clinical symptoms associated wit... 2135
Reposted by Mark GresnigtSlavica Janevska @slavi-jan.bsky.social · 06/01/2025Join our team at the Leibniz-HKI as Technical Assistant - application deadline closing soon! 📣 033
Reposted by Mark GresnigtAdaptive Pathogenicity Strategies @aps-hki.bsky.social · 02/01/2025We are excited to share that in the last few days of 2024 our review on how bacterial and fungal pathogens🦠🍄🧫 bind and/or sense immune mediators to evade and escape the immune system has been published in @femsjournals.bsky.social #FEMSMicrobiologyReviews. academic.oup.com/femsre/advan...academic.oup.comMicrobial adaptive pathogenicity strategies to the host inflammatory environmentAbstract. Pathogenic microorganisms can infect a variety of niches in the human body. During infection, microbes can only persist if they adapt adequately 042
Reposted by Mark GresnigtSimone Andrea Biagini 🏳️🌈 @sabiagini.bsky.social · 24/11/2024In the past years, I've found using comic-inspired color palettes super helpful when creating figures for my papers. Just came across this one and I’m definitely using it next! 💡Any comic recommendations with cool color palettes?🌈 #AcademicSky @academic-chatter.bsky.social @thephdplace.bsky.social 6386
Mark Gresnigt @markgresnigt.bsky.social · 22/11/2024Shocking moment today: Got told by the pediatrician today that I should open a bottle of prosecco to celebrate that our son was now through his full first set of vaccinations. Apparently is not that common anymore that people let their children be fully vaccinated 🤯 050
Reposted by Mark GresnigtAdaptive Pathogenicity Strategies @aps-hki.bsky.social · 14/11/2024In our @dfgpublic.bsky.social funded research grouop we use this system in our lab to see how Candida albicans adapts to the different host stimuli we expose it to. 011
Reposted by Mark GresnigtAdaptive Pathogenicity Strategies @aps-hki.bsky.social · 14/11/2024For our first post, we would like to share that we are enjoying how our live-cell imaging system (Funded by the state of Thuringia and co-funded by the EU) can use a neuron tool to quantify fungal hyphal growth. See the paper by Wurster et al. who established this journals.asm.org/doi/epub/10.... 172
Mark Gresnigt @markgresnigt.bsky.social · 19/11/2023This week my group started to work in our new labspace at the Leibniz-HKI after a lot of restructuring and reorganization. Happy we can finally get some experiments done in the new rooms. 050
Mark Gresnigt @markgresnigt.bsky.social · 10/10/2023Hello 👋🏼 all. Happy to join here for the science chats 181