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Pfliegler Lab at University of Debrecen

@pflieglerlab.bsky.social
195 followers 140 following 226 posts

Saccharomyces, yeasts, mycobiome, phylogenomics

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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 08/10/2026
I have finished reading the new book of @larsga.bsky.social about The Power of Beer! Absolutely stunning information overload, especially on historic trends, styles, and political economy, all from the perspectives of brewing. And of course, a lot about #yeast and how people domesticated it!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 07/10/2026
Time for some #Saccharomyces discussions and giving a talk at Wrocław Medical University!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 06/10/2026
Right after the trip to Norway I came to beautiful Wrocław to meet collaborators from the Wrocław Medical University and to talk about clinical #Saccharomyces and genomes tomorrow:)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 03/10/2026
Keptinis making is truly spectacular at @kornolfest.bsky.social
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 03/10/2026
Mika Laitinen presenting about historic daily cereal drinks of farmers
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 03/10/2026
Keptinis brewing demonstration at the Norsk Kornølfestival!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 03/10/2026
I finally got the chance to taste the Norwegian Gamalost cheese, ripened with Mucor mold! Not your usual cheese :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 03/10/2026
We are absolutely thrilled to be here in Grodås, Hornindal for the Norsk Kornølfestival to discuss #yeast , traditional fermentations and to taste an insane variety of local farmhouse ales w/ @balintnemeth.bsky.social @gergohorvath.bsky.social
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 23/09/2026
The first non-chaotic(?) week of the semester is here when we can actually get work done! We welcome two new PhD students in the Lab, Soulafa from 🇸🇾 and Gergő from 🇭🇺 who will work with #yeast and other fungi! Good luck and welcome:)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 18/09/2026
I'm very proud of my students taking part at the Genetics Miniconference in Szeged today, showing their work for the first time! We divided the posters into 10 blocks, each for a student project:) Congratulations Team! #yeast #lablife
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 25/08/2026
Finally, the only "island ale", sort of a Saaremaa Island koduõlu I could find in Tallin:
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 22/08/2026
And I also managed to buy a keptinis ale!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 21/08/2026
Finally, after hearing so much about the Jovaru Alus, the Jovaru ale from @larsga.bsky.social and his blog, I finally tasted this unique wonderful farmhouse ale in Vilnius, Lithuania!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 19/08/2026
Visiting Riga and Latvia: what a nice sight, mobile kvass vendors! #yeast
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 06/06/2026
It is always a challenge but also fun to go back to partially completed projects: this manuscript supplementary file happens to be last modified in Nov 2020... Time to wrap things up! #Saccharomyces #lablife
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 21/05/2026
Prof. Csaba Szabó from University of Fribourg giving an invited talk at our University of Debrecen on the reproducibility crisis in #science!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 20/05/2026
Most of my at-home fermentation experiments are successful, this one is not :) It took me a looooot of time to get my hands on viable and pure Monascus from red yeast rice products. After inoculating to steamed rice, the Rhizopus-like and Aspergillus-like molds took over the slow-growing Monascus:
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 12/05/2026
This week we conclude our General and Applied Microbiology Lab class with 1st year BSc students at UDebrecen. We spent the semester with studying sourdough yeasts and bacteria, with spp identification, genetic fingerprinting, and classic microbiological experiments. We also made new sourdoughs...
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 05/05/2026
Real #cask ale or real ale from the UK is a wonderful beverage often described as a "live product", with live yeasts responsible from secondary fermentation and carbonation. I found only one scientific paper on cask ale pubmed.ncbi.nlm.nih.gov/36073539/ so I had to try isolating from it in London:)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 01/05/2026
We are on a short trip in London, tasting some real #cask ale at The Lucas Arms :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 01/04/2026
Randy W. Scheckman presenting a special lecture at our University of Debrecen - he won the 2013 Nobel Prize in Physiology or Medicine for using baker’s #yeast to uncover the genetic machinery regulating vesicle transport!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 31/03/2026
Today we made great progress with a new multi-locus sequence typing approach under development for #Saccharomyces with two BSc students - this is all their work! Looking forward to analyze the sequences :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 12/03/2026
With my recent trip to Rio de Janeiro, I managed to visit 26 Terrestiral Ecoregions of the 846 existing ones to do at least some nature photography and exploration. Still a lot to go! I also visited 9 Marine Ecoriegions (of 232) and 13 Freshwater Ecoregions (of 426).
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 06/03/2026
We opened a Brazilian wild #yeast fermented red wine I brought back from Rio. Very nice, strong notes of chocolate and red fruit!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 01/03/2026
www.biorxiv.org/content/10.6... comparison of commercially available #Saccharomyces #mead yeasts. Our new preprint w/ @balintnemeth.bsky.social and colleagues compares 13 mead #yeast strains for their phenotype, genome, and presents data on metabolites in experimental mead fermentations.
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 26/02/2026
Yesterday at Rio Botanic Garden :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 25/02/2026
I arrived to the Federal University of Rio de Janeiro to André dos Santos' lab, meeting with students incl. @raquelvicente.bsky.social who visited us in Debrecen a year ago! Excited to give a course on #yeast genomics :) and present on our results in this enchanting city!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 18/02/2026
With a 2019 Fuller's vintage ale, celebrating the acceptance of a paper w/ @alexandraimre.bsky.social that we started working on in 2019. So happy to have saved this for all these years! What a long journey! The topic is #yeast probiotics, will be online very soon!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 05/02/2026
It actually causes stress in the cell wall, so a very little amount is deadly in most of the cases for yeast (I misspelled "wall" above). On this pic, the bottom 2 strains are OK in a dilution series. The top two only show growth in a spot where we inoculated 50k cells, save for one lonely colony.
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 05/02/2026
Found this almost artistic bottle, probably close to 100 years old, at our Department! Still in great shape and the Congo Red is still vibrant red inside:) this substance is often used in cell will stress experiments with #yeast
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 23/01/2026
We welcome @ola-gorzynska.bsky.social from Wroclaw Medical University in Debrecen! Ola will spend a month in our lab working on clinical #Saccharomyces yeast genomes. 54 Polish isolates' sequences just arrived, so the project starts w/ Andi Harmath and @balintnemeth.bsky.social ! Good luck, Ola!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 11/01/2026
My first ever hairy tofu, 毛豆腐. Made with a Mucor species starter culture I ordered from Ebay. After 24 hours it was ready and I stir-fried it, the taste was cheese-like and pleasant!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 19/12/2025
An incredible agART - agar art from PhD students Andrea Harmath and @balintnemeth.bsky.social, depciting our lab's activities in #yeast research from fermentations to bioinformatics :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 24/11/2025
I'm honored and excited to participate in the The Human Frontier Science Program's Grant Writing Masterclass in Prague! It is great to be in this beautiful city, with the recent snow the Czech Academy of Sciences' Vila Lanna building looks fantastic!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 23/11/2025
I first tried U Fleků and both of their house beers after arriving to Prague
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 23/11/2025
Riding the train from Budapest to Prague for a grant writing masterclass, so far a really good experience! Can't wait to see the city for the first time! #lablife
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 13/11/2025
We are having a great time at NCSU with students @balintnemeth.bsky.social and Andrea Harmath, meeting with the Crook Lab and @alexandraimre.bsky.social over probiotics, with Ignazio Carbone at CIFR over Aspergillus, and soon with the @caitismuheil.bsky.social Heil Lab over yeasts! Wonderful place!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 13/11/2025
We arrived to Raleigh, N.C. with my PhD students @balintnemeth.bsky.social and Andi, visiting collaborators including @alexandraimre.bsky.social and exploring the city! Here at Wye Hill Brewing.
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 31/10/2025
A photo I have been planning to make for a long time, at the Natural History Museum of London :) #Darwin
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 31/10/2025
And today two half-pints of cask ale at the "infamous" Ten Bells :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 30/10/2025
Now a pint of red in The Prince Edward :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 29/10/2025
So far surprisingly different from bottled beer and very fresh and zesty!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 29/10/2025
My first ever English cask ale in London. We are visiting The Old Swan after Churchill Arms! Tasting an Old Golden Hen and an Abbot Ale!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 29/09/2025
Recently I revived my experimental sourdough culture from the -80C freezer and started refreshing it every day. The khachapuri made with it tonight looks quite good:) #yeast
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 12/09/2025
Congratulations to @balintnemeth.bsky.social on his talk on thousands and thousands of #Saccharomyces genomes!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 12/09/2025
We arrived in Szeged for the annual miniconference of the Hungarian Genetics Society! My PhD student @balintnemeth.bsky.social will present about the #Saccharomyces Compendium and I have a poster about integrating #yeast research into BSc lab classes at the University of Debrecen :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 07/09/2025
This is going to be a very nice hop harvest:)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 31/08/2025
Finishing up two manuscripts while brewing a gruit with smoked malts and some fresh hops. Most of the hops I will harvest a few days later :)
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 25/08/2025
Finally, our new -80°C freezer arrived! This is our #yeast lab now, two small rooms for my research group (one half-time and one full-time PhD-student, @balintnemeth.bsky.social, many BSc and MSc-students, and me). Looking forward to start the new semester with them very soon!
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Pfliegler Lab at University of Debrecen @pflieglerlab.bsky.social · 25/08/2025
Made a nice focaccia with my #yeast experimentally evolving in wheat sourdough:)
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