iiinova — where your digital self keeps evolving

Reposted by Paul Jenkinson

Saloni @scientificdiscovery.dev · 05/09/2026

This is interesting. You get assigned to being born at a random place and time in history, to see what a typical person's life might have been like then. Unfortunately I was born in 1403 in the valley of Mexico and died at age 4 from dysentery.

anyhumanever.com

Any Human Ever

One life, drawn at random from all who have ever lived.

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Paul Jenkinson @paulmjenkinson.bsky.social · 13/03/2026

Thanks to my co-authors Keith Laws, Charlotte Dean, Aaron Clarke, Jo Mash & Rodolfo Leuzzi

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Paul Jenkinson @paulmjenkinson.bsky.social · 13/03/2026

Ever wondered if there's a relationship between self-reported interoceptive sensibility and depression? Find the answer here (free and open access). Spoiler: yes - there is! Poorer interoceptive sensibility= increased depression www.sciencedirect.com/science/arti...

sciencedirect.com

The relationship between self-reported interoception and depression: A systematic review and multilevel meta-analysis

Emerging research highlights interoceptive dysfunction as a potential mechanism underlying depression. Whereas physiological measures of interoception…

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Reposted by Paul Jenkinson

Katerina Fotopoulou @katerinafoto.bsky.social · 24/02/2026

Rome, June 2026: 1 day left to submit your abstract and award application to THE event of the year in cognitive, affective, social and embodied neuroscience! escan2026.eu check out the cool keynotes, preconferences, social and early career programme and our travel, carer and early career awards

escan2026.eu

Home - ESCAN 2026

ESCAN 2026 is the 9th ESCAN Conference, the biennial meeting of the European Society for Cognitive and Affective Neuroscience.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

📄 Open access paper: Interoception and allostatic load after stroke: A scoping review www.sciencedirect.com/science/arti...

kwnsfk27.r.eu-west-1.awstrack.me

Redirecting

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Stroke offers a unique window into how the brain constructs bodily awareness — and how its disruption shapes recovery in ways we still poorly understand.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Priorities for future work: • mechanistic studies of interoception–allostasis • standardised interoceptive assessments • integration with rehabilitation science • targeted interventions for physiological dysregulation

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

We argue that stroke research needs to move beyond isolated symptoms and adopt an allostatic–interoceptive framework that links bodily sensing, regulation, and recovery trajectories.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

This is a problem because recovery is not just motor relearning or compensation — it is physiological regulation. If the brain cannot accurately sense the body, prediction and regulation break down.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

The biggest gap: allostatic load. Despite strong links to cognition, recovery, and health disparities, it has been almost entirely neglected in stroke research.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Neuroanatomy plays a role — but the evidence is uneven. Deficits are most often linked to insula and somatosensory lesions, yet lesion mapping is inconsistently reported and rarely theory-driven.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

These are not peripheral symptoms. Interoceptive impairments are often associated with: • poorer functional recovery • cognitive dysfunction • altered body ownership/awareness • reduced independence and participation

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Key finding: interoception is frequently impaired after stroke, across multiple domains, including: • cardiac & respiratory awareness • temperature & affective touch • fatigue & energy regulation • hunger & bladder awareness

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

We conducted a scoping review of the literature on interoception and allostatic load after stroke. 👉 39 studies met inclusion criteria 👉 Only one directly assessed allostatic load That imbalance matters.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Interoception = sensing the internal state of the body (heartbeat, breathing, temperature, hunger, fatigue). Allostasis = how the brain predictively regulates these states to maintain stability. Both are central to recovery — yet rarely studied together in stroke.

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Many post-stroke symptoms don’t fit neatly into “motor” or “cognitive” boxes — fatigue, altered body awareness, disrupted breathing, blunted hunger, feeling disconnected from the body. This paper explores what happens to interoception and physiological regulation after stroke 👇

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Paul Jenkinson @paulmjenkinson.bsky.social · 20/01/2026

Delighted to share my first paper of 2026 "Interoception and allostatic load after stroke: A scoping review". Available now, open access: doi.org/10.1016/j.ne...

doi.org

Redirecting

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Jay Van Bavel, PhD @jayvanbavel.bsky.social · 18/01/2026

Writing is thinking Outsourcing the entire task of writing to LLMs will deprive us of the essential creative task of interpreting our findings and generating a deeper theoretical understanding of the world.

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Reposted by Paul Jenkinson

PessoaBrain @pessoabrain.bsky.social · 28/12/2025

𝗧𝗵𝗲 𝗘𝗻𝘁𝗮𝗻𝗴𝗹𝗲𝗱 𝗕𝗿𝗮𝗶𝗻 Annual reminder that the book is open access. How do we think of the brain as a deeply interconnected system with highly distributed, non hierarchical processing. Want to learn about the brain from a fresh perspective? #neuroskyence mitpress.mit.edu/978026254460...

mitpress.mit.edu

The Entangled Brain

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Sahib Khalsa @skhalsa.bsky.social · 16/12/2025

New writeup on interoception in Scientific American focusing on its role in mental health: www.scientificamerican.com/article/inte...

scientificamerican.com

Disruptions in This Sixth Sense May Drive Mental Illness

Disruptions in interoception may underlie anxiety, eating disorders, and other mental health ailments

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/11/2025

Delighted to announce a fully funded PhD opportunity working on a new project looking at body image problems in teenage girls. Applications now open! Full details here: www.cairnmillar.org.au/about/career...

cairnmillar.org.au

PhD Studentship in Psychology / Computational Neuroscience - The Cairnmillar Institute

Project: Expanding the body perception box in adolescent girls

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Reposted by Paul Jenkinson

derek guy @dieworkwear.bsky.social · 14/11/2025

crazy IG em_clarkson

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Reposted by Paul Jenkinson

Sam Gershman @gershbrain.bsky.social · 08/11/2025

My reviewing style has changed over time. Rather than litigate every little thing, and pushing my own ideas, I focus only on 2 things: (1) Are the claims interesting/important? (2) Does the evidence support the claims? Most of my reviews these days are short and focused.

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Reposted by Paul Jenkinson

Peter Kok @peterkok.bsky.social · 08/08/2025

We are recruiting a new PI at the FIL @imagingneuroucl.bsky.social, Associate or Full Professor. This is an amazing place to do cognitive neuroscience, in the heart of London. If you or someone you know might be interested, please pass it on. #neuroskyence www.ucl.ac.uk/work-at-ucl/...

ucl.ac.uk

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

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Paul Jenkinson @paulmjenkinson.bsky.social · 31/07/2025

Thanks Gavin. I think we'll do that. Best to speed up the rejection process 😆

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Paul Jenkinson @paulmjenkinson.bsky.social · 31/07/2025

Searches are now 12 months old—submitted before they were—but delays like this risk reviewers flagging outdated data. How are we supposed to maintain timely reporting standards when journals don’t? What shoulld we do? Withdraw? Wait it out? Anyone dealt with this?

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Paul Jenkinson @paulmjenkinson.bsky.social · 31/07/2025

Help and advice needed please Bluesky community! We submitted a meta-analysis over a month ago. It's still “with editor.” Three follow-up emails sent. Admin says they’ll chase. Still Nothing.

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cejpreston.bsky.social @cejpreston.bsky.social · 29/07/2025

New paper on body image during pregnancy! Free to download for 50 days kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Image of paper title “testing the tripartite influence model among pregnant women”

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Reposted by Paul Jenkinson

Lou Calvey @loucalvey.bsky.social · 27/07/2025

Skegness, one of your absolute finest people right here. Buy her a drink whenever you see her.

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

8/ We hope this review sparks new research into the embodied consequences of stroke—and how restoring internal regulation might support better recovery. Co-authored with: Salvato, Bassolino, Beccherle, Vianello, Fotopoulou, Bottini & Moro #Stroke #Interoception #Allostasis #Neuroscience

osf.io

OSF

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

7/ 🧠 Our conclusion: Stroke disrupts internal bodily regulation in ways that matter—but the field is just scratching the surface. We call for: ▪️ Standardised interoceptive measures ▪️ Longitudinal studies ▪️ Mechanistic insights ▪️ Rehab strategies targeting interoception

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

6/ 📉 Allostatic load—essentially the long-term physiological cost of stress—has not specifically been characterised and studied post-stroke. The one study that did measure it found that higher load predicted worse cognitive outcomes, especially in marginalised populations.

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

5/ 🧠 Interoceptive changes were often linked to poorer outcomes: ▪️ Lower functional recovery ▪️ Cognitive and emotional challenges ▪️ Disturbed body ownership Insular and somatosensory lesions were most commonly implicated.

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

4/ What did we find? Interoceptive deficits post-stroke are common. Disrupted domains include: ✔️ Heartbeat detection ✔️ Breathing awareness ✔️ Temperature and touch perception ✔️ Fatigue and hunger ✔️ Bladder and muscle sensation

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

3/ 🔍 We reviewed 39 studies: ▪️ 38 focused on interoception after stroke ▪️ Only 1 (!) specifically characterised and examined allostatic load. That gap alone speaks volumes. We need to better understand the body’s complex internal regulation systems in stroke recovery research.

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

2/ Why this matters: Interoception plays a key role in regulating internal bodily states. When the brain is damaged by stroke, this internal sense can be thrown off balance—impacting recovery, cognition, emotion, and quality of life. But how exactly? No one had mapped this—until now.

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Paul Jenkinson @paulmjenkinson.bsky.social · 28/07/2025

🧵1/ New preprint alert! We just pre-printed a scoping review exploring how stroke disrupts interoception—our sense of the internal body—and its possible effects on allostatic load (the physiological toll of chronic stress). 🧠🫁🫀🧵 Read it here 👉 osf.io/preprints/ps...

osf.io

OSF

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/07/2025

8/ We hope this meta-analysis lays a foundation for future research and clinical innovation. Thanks to co-authors Rodolfo Leuzzi, Charlotte Dean, Aaron Clarke, Joanna Mash, and Keith Laws 🙏 📝 Read the preprint here: 🔗 osf.io/abep4 #interoception #depression #mentalhealth #OpenScience

media.tenor.com

a woman in a black top is smiling and says thank you

ALT: a woman in a black top is smiling and says thank you

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/07/2025

7/ Implications? 🛠️ Interoceptive-based therapies should focus on regulation, self-trust, and metacognition—not just improving accuracy. 🧪 And future research should carefully choose tools that reflect adaptive vs. maladaptive interoceptive processes.

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/07/2025

6/ We interpret this in line with Allostatic Self-Efficacy theory—depression may emerge when people lose confidence in their ability to regulate internal states. 🧩 These findings support a multidimensional model of interoception, where not all interoceptive tools are created equal.

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/07/2025

5/ Between-group studies (depressed vs. controls) showed stronger effects than symptom-based correlations in healthy samples. And interestingly, not all self-report tools agreed—MAIA showed strong links; others (like BPQ, BRQ) showed positive or mixed associations.

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/07/2025

4/ This suggests that how people interpret and regulate their internal states—not just how accurately they detect them—is crucial in depression. Regulatory & metacognitive interoceptive processes may be promising targets for intervention.

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Paul Jenkinson @paulmjenkinson.bsky.social · 25/07/2025

3/ We found a significant negative association between self-reported interoception and depression (r = -0.17). That is, poorer interoception = higher depression. The effect was strongest for: 🧘‍♂️ Self-regulation 🎯 Attention regulation 🙏 Trusting bodily signals

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