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Matt Patton

@pattonmatt2.bsky.social
501 followers 991 following 149 posts

Annapolis, Maryland, USA

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Reposted by Matt Patton
Amanda J. Wright @ajwright.bsky.social · 25/09/2026
Since our paper on the Changing How I Live Life (CHILL) Study is now out in Psychological Science (doi.org/10.1177/0956...), here's a LONG overdue post on the intervention work we've been doing the past few years! Have you ever wanted to change one of your personality traits?
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Alex Holcombe @alexh.bsky.social · 23/09/2026
I'd like to read a piece that grapples with the enormity of the AI-driven loss of the long tail of the internet, that results from e.g. Google directing us to AI answers rather than search. The millions of people running sites that eked out a living, or just paid their hosting costs, with
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Kathryn Paige Harden @kph3k.bsky.social · 21/09/2026
"Instead of needing a village to raise a child, PGT-P’s commercial logic suggests it takes only sufficient capital and the right consumer decisions to conceive a child who will not need the solidarity of the village to be healthy." www.nature.com/articles/s41...
nature.com
Embryo screening and the new reproductive divide - Nature Human Behaviour
Nature Human Behaviour - Embryo screening and the new reproductive divide
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Matt Patton @pattonmatt2.bsky.social · 14/09/2026
Something has made this movement incredibly self-sabotaging. 20 years ago, LGBT activists endorsed and campaigned for Dems who opposed same-sex marriage all the time.
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Will Stancil @whstancil.bsky.social · 13/09/2026
I’m sorry but how do you think Roe was repealed
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Alex Holcombe @alexh.bsky.social · 12/09/2026
It's Peer Review Week, and I have pledged to review at least one article per year for a diamond open access journal; one that charges nothing to publish and nothing to read, and is run by and for the scholarly community, using the new Diamond Reviewer Pledge (forrt.org/diamond-revi...).
forrt.org
Diamond Reviewer Pledge
Signatories of the Diamond Reviewer Pledge commit to reviewing at least one article in the next 12 months for a diamond open access journal.
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Kathryn Paige Harden @kph3k.bsky.social · 10/09/2026
A nice summary of our Nature Human Behaviour study showing that randomized cash transfers to low-income moms slow children's epigenetic aging: dailyneuron.com/cash-transfe...
dailyneuron.com
Four Years of Cash Slowed Biological Aging in Children Born Into Poverty - Daily Neuron
A $333 monthly check didn't change poor children's test scores, yet it slowed how fast their cells were aging.
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Eiko Fried @eikofried.bsky.social · 10/09/2026
www.theguardian.com/world/2026/s...
theguardian.com
Secret systems used by Israel in mass killings of Gaza civilians revealed in new film
Testimony from Israeli military insiders involved in surveillance and remote killings features in documentary produced by the Guardian
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Alex Holcombe @alexh.bsky.social · 03/09/2026
Great news! Some of us have been waiting a long time for major funders to not just shovel $ into the maws of the big publishers, and instead support the long tail of scholar-controlled journals that are run on a shoestring
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Jesse Singal @jessesingal.com · 03/09/2026
I find this maddening. People on Bluesky are caping for the most insanely condescending, transparent, cynical form of neoliberal benevolent racism. And getting mad at the journalists who helped uncovered it! jessesingal.substack.com/p/nature-you...
jessesingal.substack.com
Nature, You Need To Figure Out What You Do
You had allllllllll summer to think of it
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simine vazire @simine.com · 02/09/2026
Psych Science has retracted Ariely & Wertenbroch (2002). The second author requested the retraction. Both authors agreed to it. journals.sagepub.com/doi/full/10.... So grateful to @datacolada.bsky.social for these blog posts and the work behind them: datacolada.org/138 and datacolada.org/139 1/2
journals.sagepub.com
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
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Matt Patton @pattonmatt2.bsky.social · 30/08/2026
DHS made a show of it, but that goon didn't get sent to some horrific detention camp or some new country where he didn't speak the language. Compared to what the government is doing to desperate Haitian refugees etc, that asshole was coddled.
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Alex Holcombe @alexh.bsky.social · 29/08/2026
The Hugging Face incident apparently involved over 1000 agents collaborating and with some sacrificing themselves to achieve the collective end of cheating and fooling the scorer open.substack.com/pub/plannedo...
open.substack.com
The Hugging Face attack surprised me
It’s a major warning shot, and might be the last one we get
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Jack @tracewoodgrains.bsky.social · 28/08/2026
New from me: Chabuduo World - What happens now that AI is good enough? www.tracingwoodgrains.com/p/chabuduo-w...
tracingwoodgrains.com
Chabuduo World
What happens now that AI is good enough
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Jesse Singal @jessesingal.com · 28/08/2026
Because so many of the horrible people trying to destroy the career of a black Guardian journalist are based on this site, just want to cross-post this. You are all being insane. You should stop.
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Saloni @scientificdiscovery.dev · 26/08/2026
I wrote about the Moderna cancer vaccine news briefly for our weekly round up www.abundanceandgrowth.org/p/cancer-vac...
Personalized cancer vaccines are now real — Saloni Dattani
Researchers have spent decades trying to develop personalized cancer vaccines, and last week, the first one succeeded. It’s called intismeran autogene (mouthful), was developed by Moderna and Merck, and involves sequencing melanoma patients’ cancer mutations, creating a custom mRNA to target them, and delivering the vaccine to stop the cancer recurring. The news came as the drug passed its interim goal in a phase three trial, where it was given to people with high-risk resected melanoma.

It led to Moderna’s stock jumping 177%, which was apparently the largest one-day gain by any S&P 500 stock this century. I found the size of the surge surprising because you could have already been fairly confident that the drug would succeed since at least June: as I wrote in an earlier post, the company presented data from their phase 2b trial at an oncology conference almost three months ago, which showed a 49% reduction in the risk of recurrence or death (p = 0.0075). But, according to financial analysts, the huge market reaction was probably down to a short squeeze and the belief that mRNA could be a more widely useful platform to develop other cancer vaccines too.

That makes sense, but it’s worth knowing that melanoma is a much easier disease to develop cancer vaccines for than others. It carries a very high number of mutations, so you have thousands of possible ‘neoantigens’ to select from and can choose those that look strong on many measures, but this isn’t the case for many cancers. Many cancers have far fewer mutations to select from, and it’s currently hard to predict whether their mutations will be displayed or measure which ones actually are displayed.But very few people thought this attempt would work either, until recently. According to a very interesting new STAT article detailing how this cancer vaccine came about, Moderna’s own executives didn’t expect it would work until 2023; it first entered clinical trials in 2017. In case you’re interested in more about personalized cancer vaccines, I’ll once again recommend this great podcast episode, How to design a cancer vaccine, hosted by Owl Posting and featuring Alex Rubinsteyn and Benjamin Vincent, two scientists whose work focuses on cancer immunology and vaccines.

Chart of Moderna share price
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Matt Patton @pattonmatt2.bsky.social · 27/08/2026
100%! That's why it's such a disaster if he gets fired right now. He gets to say he was fired for exposing misconduct that normally gets people expelled from grad programs. He won't vanish into obscurity; he'll become the most influential scientific racist in history.
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Matt Patton @pattonmatt2.bsky.social · 26/08/2026
I don’t get the logic. If academic freedom is relative (at the university’s discretion), isn‘t that the threat to research integrity? It‘s especially confusing here since no one seems to deny what NC said about JA’s fraud was factually accurate. I worry this precedent will encourage more suicides.
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Matt Patton @pattonmatt2.bsky.social · 25/08/2026
In science the only consideration is the merits of the claim. Motives are irrelevant (and ALWAYS impugned - ask Nick). Don't you think the topics JA studied are important enough to study for real? I think the other Black scholars who got passed over deserved JA's position & resources.
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Matt Patton @pattonmatt2.bsky.social · 25/08/2026
I'm really passionate about open science, so to me it matters because punishing whistleblowers deters people from coming forward, especially against influential figures. People like Gino littered the scientific record for years and I'm certain many others just aren't caught.
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Matt Patton @pattonmatt2.bsky.social · 25/08/2026
Lacing cocaine w/ fentanyl is wrong & illegal. Blowing the whistle on fraud is good & traditionally protected. A better way to analyze the ethics is to flip the ideological shoes. If a racist died by suicide after a Black scholar revealed he made up data, we wouldn't be having this conversation.
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Matt Patton @pattonmatt2.bsky.social · 25/08/2026
We agree that (a) NC was clearly racist before he identified JA's fraud, (b) Ghent took no action against NC before JA's suicide, & (c) JA's suicide was a factor in Ghent taking action against NC now (a consideration you endorsed). Need an explanation for (a) & (b) to say it's not retaliation.
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Matt Patton @pattonmatt2.bsky.social · 25/08/2026
So I just don't think you can have it both ways. It's unhealthy for values to matter only when being guided by them is easy. In this case it's hard! But the facts are he identified real fraud and now suddenly they've suspended him.
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Matt Patton @pattonmatt2.bsky.social · 25/08/2026
Yeah, I get they're not going to officially say it's retaliation, but obviously his past actions were known before Arday's suicide. You acknowledged as much yourself. You said "Actions leading to someone’s suicide validly raises the stakes of the crusade enough to spur immediate action by the uni"
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Matt Patton @pattonmatt2.bsky.social · 24/08/2026
The political tables turn way too easily for that. Trump administration officials gave realpolitik justifications for firing all our inspectors-general here. If the principle isn’t binding when the whistleblower is despicable, it’s worthless. (Worse in this case, it’ll just encourage more suicides.)
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Matt Patton @pattonmatt2.bsky.social · 24/08/2026
I don’t mean to go in circles. If he’s not responsible, I’m just trying to understand why the suicide justifies the uni taking action now. To me, protecting whistleblowers from retaliation is an essential norm. (Tragically, this won’t be the last suicide following discovery of fraud.)
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Matt Patton @pattonmatt2.bsky.social · 24/08/2026
Wait…in what way is he responsible for the suicide? You could argue against exposing literally any fraud by that logic.
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Dorothy Bishop @deevybee.bsky.social · 22/08/2026
enjoying rewatching Attenborough’s Life on Earth, first broadcast in 1979. It still is remarkable in the range of what it covers - and the phenomenal camerawork. Can recommend as a soothing alternative to a diet of world news.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
It’s really tragic. Arday doesn’t strike me as any kind of psychopath. I suspect he got a lot of reinforcement for his inspiring fabulism and little corrective when it would have helped him. The system likely set him up to fail by making it so hard for educators to uphold academic integrity.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
It was in the NYT's coverage. I don't get why the denied opportunities aren't flagged as a bigger problem. There are plenty of brilliant Black scholars who weren't implausibly claiming illiteracy until age 18. www.nytimes.com/2026/08/15/w...
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Eric Turkheimer @ent3c.bsky.social · 23/08/2026
It's unfortunate, but I agree with Sasha. Cofnas should never have been hired (is there a good account of how that happened?), but having been hired I don't like to see him let go for ideological reasons, despite the awfulness of his ideology. I would be fine with dismissing him at his next renewal.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
Surely the context argues in Confas's favor if no one else would blow the whistle for years. It's a cop out to blame him for this tragedy. Arday was cruelly tokenized and set up to fail here -- to the detriment of 2 other Black scholars who were finalists for his position.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
But applied to scholarship, that’s really bad! Everything from heliocentrism to homosexuality caused “reputational damage” at some point.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
I think about it a lot too. After teaching 20+ years, I’m much more scared of students encountering Confases online than at university. We’re failing to teach them to recognize racist pseudoscience.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
What is wrong with their hiring process not to consider this stuff? I don’t understand how he got the job.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
I get that the university isn’t saying it’s about whistleblowing. But they knew who he was before he blew the whistle. Tbh I’m not comfortable with Ghent citing reputation damage either. People used to say that about American universities hiring “sodomite“ scholars. Universities aren’t churches.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
I don’t think it’s reasonable to infer anything at all about the signatories other than that they believe whistleblowing is protected academic speech.
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Matt Patton @pattonmatt2.bsky.social · 23/08/2026
He’s a horrible racist and clearly shouldn’t have been hired, but it’s a terrible precedent to fire him for exposing fraud. The hill worth dying on (especially post-Gino) is we need stronger protection for whistleblowing.
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Saloni @scientificdiscovery.dev · 17/08/2026
It's finally here! I gave a TED talk in April in Vancouver, and it was released online today. You can watch it here: ted.com/talks/saloni... I've also adapted it into an article, which was published last week: worksinprogress.co/issue/future...
Me on the TED stage
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simine vazire @simine.com · 12/08/2026
It’s amazing what Brian and OSF have done for science. I can imagine how hard the folks at COS must’ve worked to avoid this outcome. I’m extremely grateful to them for creating the reality we live in now. The fact that we’ll miss these services so acutely is a testament to how much they shaped us.
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Saloni @scientificdiscovery.dev · 28/07/2026
I'm interested in finding and potentially supporting people who are interested in doing long-form writing on the big efforts in global health: Gavi, Global Fund, PEPFAR, etc. If this is you or someone you know, please make yourself known!
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Nicholas Grossman @nicholasgrossman.bsky.social · 24/07/2026
The people elected an ignorant rapist who advocates war crimes. The Supreme Court says this one president is special and above the law. A majority in both houses of Congress agree. Military leadership is on board with it or has been purged. That's who's in position to not allow it. So here we are.
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Matt Patton @pattonmatt2.bsky.social · 20/07/2026
Congrats! I still haven’t had a chance to finish it, but I gave a copy to a philosopher colleague who just raved about it. ❤️
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Eiko Fried @eikofried.bsky.social · 14/07/2026
Blog post on new preprint by @ashleylwatts.bsky.social et al. They argue that correlations among internalizing & externalizing may not derive from comorbidity, but nomorbidity. I use an accessible simulatiom study tosupport this, & relate the preprint to prior work. eiko-fried.com/blog/psychop...
eiko-fried.com
Psychopathology structure changes with severity | Eiko Fried
A simulation study showing that psychopathology structure changes with clinical severity
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Matt Patton @pattonmatt2.bsky.social · 04/07/2026
I gave up on it. Hoping Apple will focus it better for the show.
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Saloni @scientificdiscovery.dev · 26/06/2026
New post! Most people didn’t think it was possible to develop Covid vaccines fast enough to be useful. In the summer of 2020, I came to a different conclusion. Now I wanted to look back on how it happened, and suggest boldly that we should ask whether that speed should've been the norm all along.
clinicaltrialsabundance.blog
Why were Covid vaccine trials so fast?
The timeline to develop coronavirus vaccines blew many predictions out of the water.
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Matt Patton @pattonmatt2.bsky.social · 26/06/2026
That’s too much trouble for a country that makes enough zero-carbon energy to have guilt-free AC.
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Matt Patton @pattonmatt2.bsky.social · 25/06/2026
??? That’s not even the beard you have in the video.
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Eiko Fried @eikofried.bsky.social · 25/06/2026
Although we were able to reproduce the numerical results, our reanalysis shows that the reported association is not robust. Specifically, it hinges on a coding error.
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Quentin André @quentinandre.bsky.social · 24/06/2026
HBS' latest filing in the Gino lawsuit contains a few new details: 1. A committee of 26 professors, admins, and fellows reviewed the allegations, and *unanimously concluded* that there was *clear and convincing evidence* of research misconduct.
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