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Pedro Santamaria

@p-santamaria.bsky.social
207 followers 270 following 2.2K posts

Retired researcher in Developmental Genetics, Evo-Devo. Drosophila. Polycomb Group. (PRC genes. "polyhomeotic" etc.), Nuclear transplantation in the egg. Cell mosaics and chimeras. Epigenesis in Drosophila. Atheist. Hobby: mosaics.

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Pedro Santamaria @p-santamaria.bsky.social · 19h
- Exploring how sequence and chromatin changes cause de novo gene expression in #Drosophila. academic.oup.com/genetics/art...
academic.oup.com
De novo genes originate in regions of ancestrally closed chromatin
Abstract. The evolution of de novo genes from ancestrally nontranscribed sequences has been reported in a wide range of taxa. However, the DNA sequence cha
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Pedro Santamaria @p-santamaria.bsky.social · 20h
- You're not going to let this "ketamine jackass" win ! Right ? www.newsweek.com/french-crisi...
newsweek.com
French Crisis Strengthens Trump’s Case Against Europe
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Pedro Santamaria @p-santamaria.bsky.social · 21h
- Well ! And yet them work ! Chromosomes aren’t carefully folded DNA—they’re dual-phase gels | Journal Club | PNAS www.pnas.org/post/journal...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Pedro Santamaria @p-santamaria.bsky.social · 21h
Even we, who know some of them closely, lack a comprehensive overview. www.nature.com/immersive/d4...
nature.com
Can you name the women who have won a science Nobel prize?
Take Nature’s quiz on female Nobel laureates in physics, chemistry or physiology or medicine.
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Pedro Santamaria @p-santamaria.bsky.social · 21h
- The more Nationalist or Christian you are, the lower your cognitive abilities. - We ought to have known it without any need for scientific confirmation. www.psypost.org/lower-cognit...
psypost.org
Lower cognitive ability is linked to stronger Christian nationalist views, even after accounting for education
A recent study indicates that Americans with lower cognitive ability scores tend to be more likely to embrace Christian nationalism. The findings suggest the ideology’s appeal is linked to underlying ...
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Pedro Santamaria @p-santamaria.bsky.social · 21h
From now on, it will be very complicated trusting what we perceive ! www.nature.com/articles/d41...
nature.com
This award-winning microscopy image used AI — igniting controversy in a prestigious competition
Researchers say that using artificial-intelligence tools to visualize scientific images can become problematic when models misrepresent the underlying data.
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Pedro Santamaria @p-santamaria.bsky.social · 02/10/2026
Zimmer = Peter Thiel. Panoptik = Palantir. Les "Mouches à fruit" = des politiques comme Dolad T. actu.orange.fr/monde/giulia...
actu.orange.fr
Giuliano da Empoli sur l'IA : "Le véritable grand remplacement, c'est celui du réel par le numérique" : Actualités - Orange
Entretien. Avec "Le Fondateur", en librairie le 1er octobre, Giuliano da Empoli entre dans la tête des géants de la tech, et en particulier du plus fascinant d'entre eux : Peter Thiel.
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Reposted by Pedro Santamaria
Genes & Development @genesdev.bsky.social · 01/10/2026
RESEARCH PAPER: Differential control of both cell cycle-regulated and quantitative histone mRNA expression by Drosophila Mute By Geisler et al. and Robert Duronio ➡️ genesdev.cshlp.org/content/40/19-20… Mark Geisler #histone #replication #mRNA #Drosophila
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Pedro Santamaria @p-santamaria.bsky.social · 02/10/2026
- "The world through more than 100 lenses, each of which is an inflated nylon ball working as a pinhole camera. The effect is meant to Suggest how insects see the world". - Does not reflect how an insect perceives things at all !! They integrate !! (as us !) www.nature.com/immersive/d4...
nature.com
Gaze into the cosmos and through the eyes of a bee — September’s best science images
The month’s sharpest science shots, selected by Nature’s photo team.
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
Tout change ! Gif-sur-Yvette : le campus du CNRS devient un laboratoire grandeur nature pour la biodiversité | top, actu locale share.google/I1xgCcqijnhi...
share.google
Gif-sur-Yvette : le campus du CNRS devient un laboratoire grandeur nature pour la biodiversité | top, actu locale
Le campus CNRS de Gif-sur-Yvette devient le premier site pilote de son Observatoire de la biodiversité pour suivre et préserver la faune et la flore. Le campus CNRS de Gif-sur-Yvette devient le premie...
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
C'est déjà complet. Mais je me demande, Comment vont ils aborder le thème : "Entre Science et Croyance" ( le jour d Halloween). www.iledefrance-gif.cnrs.fr/fr/evenement...
iledefrance-gif.cnrs.fr
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
And in Biology ?? Five physics breakthroughs that should have won a Nobel Prize—but didn’t | Science | AAAS www.science.org/content/arti...
science.org
Five physics breakthroughs that should have won a Nobel Prize—but didn’t
How politics, bad timing, and skepticism left foundation stones of modern physics unrecognized
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
- No right-minded person can respect a self-absorbed narcissist ! - Whatever is not Natural is necessarily Artificial ! - But the suck-up, hypocritical, moguls are the absolute worst. gizmodo.com/trump-clearl...
gizmodo.com
Trump Clearly Expects AI Leaders to Go Along With His 'Super Intelligence' Rebrand. Will They?
Trump seems to be claiming that private sector AI leaders are on board with this.
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
- The gap between us and the other primates is closing. We will have to learn to step down from the pedestal that makes us in the likeness of a imaginary God. www.sciencealert.com/primate-comm...
sciencealert.com
Primate Communication May Follow Grammar Patterns Once Thought Uniquely Human
Human languages are complex and versatile.
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
www.cnrs.fr/fr/actualite...
cnrs.fr
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
- That's fascinating ! The proprioception of trees ! theconversation.com/comment-les-...
theconversation.com
Comment les arbres ajustent activement leur posture pour rester le plus droits possible
Les arbres perçoivent leur courbure et la rectifient activement grâce à un bois spécial dit « bois de tension », de manière analogue au contrôle postural des animaux.
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Pedro Santamaria @p-santamaria.bsky.social · 01/10/2026
- Do you know where the "nose" of a Drosophila fly is ? - In some chemosensory bristles. - But our five senses are probably neither exactly five, nor the same in other animals ! theconversation.com/comment-lodo...
theconversation.com
Comment l’odorat nous aide à comprendre l’origine et l’évolution de notre cerveau
L’odorat est un sens tout à fait particulier du point de vue cérébral : c’est notre lien le plus direct avec le monde extérieur, et il semble avoir très peu changé au cours de l’évolution.
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Pedro Santamaria @p-santamaria.bsky.social · 30/09/2026
- That can't happen to a fruit fly. Even if almost everything can be extrapolated from Drosophila developmental genetics. - Do you know why ? www.smithsonianmag.com/smart-news/t...
smithsonianmag.com
Two Heads Are Better Than One: Rare, Double-Headed Turtle Hatchling Discovered on Cape Cod
The tiny diamondback terrapin was brought to a wildlife center on September 17. At the time, the creature weighed about as much as a nickel
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Pedro Santamaria @p-santamaria.bsky.social · 30/09/2026
Even scientists can be fooled. Vanity is the entry point. Exclusive focus on a single theme is detrimental to alternative areas of concentration. That is why a great scientist can be socially awkward, and a Nobel prize winner be a believer of absurd religious Myths. www.nature.com/articles/d41...
nature.com
Exclusive: Sham scientific societies are misleading star researchers
A Nature investigation reveals a network of organizations that have been building their ranks through deceptive practices.
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Pedro Santamaria @p-santamaria.bsky.social · 29/09/2026
Des génes spécifiques ont dû s'exprimer à différents moments pour faire cela : Akène et cupule de Quecus ilex. Île-de -France. Aujourd'hui.
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Pedro Santamaria @p-santamaria.bsky.social · 29/09/2026
Pour les oiseaux on dit qu'ils volent en nue ou murmuration. Por les poissons on dit qu'ils nagent en banc ou école. Et pour les insectes volant en groupe ?
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Pedro Santamaria @p-santamaria.bsky.social · 29/09/2026
Even ancient Myths have precursors ! In fact, yet in Nature, familial altruism exists. Religions, all of them, reflect the paradigms of their time. They are contingent, circumstantial, and fleeting. But people are narrow-minded due to a lack of perspective ! secularhumanism.org/2026/09/stra...
secularhumanism.org
Stranger Danger: How Bart Ehrman’s Latest Unmasks the History of Altruism | Free Inquiry
Anyone today who cites the Bible to make moral objections to homosexuality or premarital sex becomes an easy target for a certain critical question: Why fol ...
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Pedro Santamaria @p-santamaria.bsky.social · 28/09/2026
Les joies du Népotisme. Maintenant le gendre Gabriel Sénateur. Comme à l'autre extrême. La Famille.
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Reposted by Pedro Santamaria
Epigenome Technologies @epigenometech.bsky.social · 28/09/2026
Epigenetics Update - HOMEODOMAIN-LIKE shapes chromatin architecture and rewires leaf epidermal patterns www.nature.com/articles/s41... Ansar Ali and Chin-Min Kimmy Ho (Academia Sinica) in Nature Communications #Epigenetics #Chromatin #Plants #Leaf --- Discover the breakthrough: epigenometech.com
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Pedro Santamaria @p-santamaria.bsky.social · 27/09/2026
Erreur !! www.vaticannews.va/fr/pape/news...
vaticannews.va
Léon XIV demande à «veiller sur la personne souffrante et non la supprimer» - Vatican News
Le Pape est allé à la rencontre des malades et des hospitaliers à Lourdes ce dimanche. Lors de cette rencontre à l’Accueil Notre-Dame du sanctuaire ...
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Pedro Santamaria @p-santamaria.bsky.social · 27/09/2026
A 14 ans (!), Bernarde affirme avoir été témoin de l'apparition d'une morte depuis longtemps supposée etre vierge-mère (!). Pourquoi c'est toujours les faibles d'esprit qui croient aux miracles ? Mais le plus absurde est qu'aujourd'hui des gens cultivés y "croient". www.lemonde.fr/societe/arti...
lemonde.fr
Visite du pape en France : les violences sexuelles au sein de l’Eglise, une « plaie encore ouverte » pour Léon XIV
Dimanche 27 septembre, le souverain pontife doit rencontrer sept victimes, à Lourdes. Alors que les évêques français ont été à la pointe sur le sujet, grâce à la reconnaissance d’un phénomène systémiq...
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Pedro Santamaria @p-santamaria.bsky.social · 27/09/2026
And some of them are in "ladino" ( ou djudezmo) ! And a few of them are still sung in Spain. www.mahj.org/fr/programme...
mahj.org
Événement : Journée en famille : En avant la musique !
Événement : Le temps d’une journée, le musée se met au diapason des musiques et des chansons des répertoires juifs.
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Pedro Santamaria @p-santamaria.bsky.social · 27/09/2026
But, in fact, it's the other way around ! It is because cells forget their fate that they lose their identity ! Polycomb mutants disrupt the roles of PRC1 and PRC2. When cells lose their identity, they also lose tissue affinities. And begin to divide again ! magazine.hms.harvard.edu/articles/how...
magazine.hms.harvard.edu
How Cancer Cells Decide Their Fate
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Reposted by Pedro Santamaria
bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 25/09/2026
Clonal hematopoiesis-associated DNMT3A mutations derepress bivalent Polycomb target genes and enhance macrophage migration www.biorxiv.org/content/10.64898/20…
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Pedro Santamaria @p-santamaria.bsky.social · 26/09/2026
- It's always a pleasure to create mosaics, be they genetic or made of tesserae. - The human achievement is always inferior to the achievement of Nature. (Without turning to the Myth of a God). - Sometimes mosaics, too, are chimeras !
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bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 24/09/2026
The Scm FCS finger binds the Pcl Tudor domain to link canonical PRC1 and PRC2.1 in Drosophila www.biorxiv.org/content/10.64898/20…
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
- Still epigenesis. The regulation of gene expression is affected by fall. - Why trees shed their leaves, and why some don’t. - As a good old Spaniard, I prefer the evergreen oaks. www.agenciasinc.es/Reportajes/M...
agenciasinc.es
Misterios del otoño: por qué los árboles pierden la hoja, y por qué algunos no
El despliegue de colores que precede a la caída de la hoja convoca cada año a más visitantes a los lugares donde puede contemplarse en todo su esplendor. Este espectáculo natural esconde una biología ...
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
Have you seen that ? What are you afraid of ? posthumain.com/intelligence...
posthumain.com
Claude d'Anthropic découvre un système génétique de type CRISPR
L'IA d'Anthropic a ratissé seule des millions de bases d'ADN pendant 21 heures et repéré un système enzymatique inédit qui rappelle CRISPR. Personne, pas même Anthropic, ne sait encore à quoi il sert.
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
- Quelle envie d'être consensuels ! Le jour qu'on recevra (pour 27 millions d'Euros) le Grand Mamamouchi ou le Guru Suprême ou le Spaghetti Volant avec tant d'égards dans un pays laïque (ou 50% n'ont pas de religion). - Tout cela en 2.026 AE... ou 4.000 000 of Homo. www.lemonde.fr/idees/articl...
lemonde.fr
Le pape Léon XIV imprime sa méthode, sans rupture avec l’héritage de François
ANALYSE. Apaisant vis-à-vis de la curie, adepte d’un style plus formel sur la scène diplomatique, le souverain pontife américain renouera avec la tradition en passant par Paris et Lourdes, étapes boud...
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
- Previously unknown “mitochondrial plaques” in Alzheimer’s disease brains - So choose who will be your mother. www.psypost.org/scientists-d...
psypost.org
Scientists discover previously unknown "mitochondrial plaques" in Alzheimer's disease brains
When the brain's cellular recycling system breaks down in Alzheimer's disease, damaged mitochondria pile up inside nerve fibers. Researchers have now identified these clusters as "mitochondrial plaque...
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
A coworker better than yourself ? Come on! AI doesn't have any imagination ! www.nature.com/articles/d41...
nature.com
AI co-scientists are revolutionizing how research is done
Artificial-intelligence systems can generate hypotheses, design experiments and analyse data — but humans still need to decide what makes sense.
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
That is why we run away from the "vulgum pecus". The one who "chirps"🐦(now they ✖️). news.harvard.edu/gazette/stor...
news.harvard.edu
‘Lately, my algorithm is trash’ — Harvard Gazette
Are we shaping our feeds or are they shaping us — and is this healthy? Faculty weigh in recommendation algorithms.
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Pedro Santamaria @p-santamaria.bsky.social · 25/09/2026
For a researcher there are no taboos. We are not here to practice medicine. For us the only appeal is the originality or the skillfulness, or cleverness, of the experiment. We leave the care and its "building upon" to the 😉doctors. news.harvard.edu/gazette/stor...
news.harvard.edu
The healing power of gene therapy — Harvard Gazette
How researchers are seeing their work changing lives — from restoring children’s hearing to saving a baby born with a fatal disease
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Pedro Santamaria @p-santamaria.bsky.social · 24/09/2026
Great ! www.embl.org/news/people-...
embl.org
Exploring humanity's shared history through paleogenetics | EMBL
Svante Pääbo, Nobel laureate and 2026 EMBL Kafatos Lecturer, discusses what his research reveals about the origins of Homo sapiens
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Reposted by Pedro Santamaria
fly paper broadcast @fly-broadcast.bsky.social · 22/09/2026
Drosophila Scm self-assembles into PcG bodies to recruit PRC2.1 to target genes during Polycomb silencing initiation #Drosophila
pubmed.ncbi.nlm.nih.gov
Drosophila Scm self-assembles into PcG bodies to recruit PRC2.1 to target genes during Polycomb silencing initiation #Drosophila
PubMed link
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Reposted by Pedro Santamaria
Riley Mangan @rimangan.bsky.social · 23/09/2026
I'm thrilled to share that a study I co-led leveraging T2T human and ape genomes to expand and refine our identification of rapidly evolved regions in the human genome is now published in Cell Genomics! Paper: doi.org/10.1016/j.xg...
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Pedro Santamaria @p-santamaria.bsky.social · 23/09/2026
'Epigenetic' editing is here: gene-tagging technique banishes hepatitis B virus www.nature.com/articles/d41...
nature.com
'Epigenetic' editing is here: gene-tagging technique banishes hepatitis B virus
Technique uses chemical tags to shut down viral DNA lurking in host’s genome.
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Pedro Santamaria @p-santamaria.bsky.social · 23/09/2026
Considering their human qualities, they were right to doubt ! Just look at who is getting elected now ! news.harvard.edu/gazette/stor...
news.harvard.edu
Democracy? Some founders were skeptical. — Harvard Gazette
Historians detail how, why Constitution became (and remains) work in progress.
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Pedro Santamaria @p-santamaria.bsky.social · 23/09/2026
- Qui peut douter que : Itamar Ben-Gvir, Bezalel Smotrich et même Benyamin Netanyahu sont des gens "pas raisonnables" ? (unfair). - (Like Putin or "the Don") - Donc E. Macron a raison : (🔝) They promote "The return of the law of the jungle". www.lemonde.fr/internationa...
lemonde.fr
« Un spectacle qui nous fait honte à tous » : les images du discours d’Emmanuel Macron à l’Assemblée générale de l’ONU
Vidéo - Le président français a appelé à dénoncer une « paix prétendue » qui n’a « pas rouvert les voies humanitaires » à Gaza. Il a aussi appelé à un « double moratoire » sur les frappes contre les s...
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Pedro Santamaria @p-santamaria.bsky.social · 22/09/2026
- "Although there was a safety pilot onboard the aircraft for precaution, they did not need to intervene at any point during the flight". - Tell it to the Ukrainians. They will be able to turn it into a weapon. gizmodo.com/autonomous-p...
gizmodo.com
Autonomous Plane Becomes the First to Fly Coast to Coast on Its Own
The aircraft flew a distance of 3,199 miles (5,148 km) without needing control inputs from an onboard safety pilot.
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Pedro Santamaria @p-santamaria.bsky.social · 22/09/2026
That's why the senile Don, on top of TACO, will always be wrong, will always be mistaken. posthumain.com/intelligence...
posthumain.com
Course à l'IA USA-Chine : qui gagne vraiment ?
Les États-Unis investissent 23 fois plus que la Chine dans l'IA. Pourtant l'écart de performance a presque disparu, et la vraie course se joue ailleurs : électricité, robots et adoption.
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Pedro Santamaria @p-santamaria.bsky.social · 22/09/2026
The same question could be asked to fruit flies (Drosophila) with my mosaics or chimeras ! www.nature.com/articles/d41...
nature.com
How to make a brain: new experiments challenge existing picture
Research also uncovers an efficient way to grow hindbrain cells from stem cells — a difficult feat.
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Pedro Santamaria @p-santamaria.bsky.social · 22/09/2026
The New Hampshire is "not yet" Europe ! But he approaches. religionunplugged.com/news/new-ham...
religionunplugged.com
The Curious Case Of America’s Most Atheist State
(ANALYSIS) Nearly half the state sits squarely outside organized religion. Granite Staters appear to regard centralized hierarchies, including church officials, with something resembling contempt. The...
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Pedro Santamaria @p-santamaria.bsky.social · 22/09/2026
- Daniel Dennett say that: "The internet was the best thing to happen to atheism since Darwin"... - Even if correlation does not imply causation. In fact, religious decline correlates with the rise of culture. www.psypost.org/new-study-li...
psypost.org
New study links the spread of the internet to a global decline in religious identity
As internet access spreads across the globe, formal religious affiliation tends to fall. A new study of 81 countries links three decades of digital expansion to a steady decline in traditional religio...
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