Sign in

Orestis Savva

@orestissavva.bsky.social
45 followers 87 following 1 posts

Just another PhD student trying to make it in this world 🌎 White Rose 🏵 DTP (Sheffield) 🇨🇾🇬🇷

PostsRepliesMedia
Reposted by Orestis Savva
preLights @prelights.bsky.social · 13/08/2026
Chlorophyll keeps the world breathing - ever wondered how it is made? @orestissavva.bsky.social covers work from @dmitryshvarev.bsky.social et al. #preprint “This work adds to our fundamental understanding of the world around us...” #PlantBiology #preLight⬇️ prelights.biologists.com/highlights/s...
prelights.biologists.com
Structure of chlorophyll synthase in complex with the LHC-like protein HliD - preLights
Chlorophyll keeps the world breathing - ever wondered how it is made?
044
Reposted by Orestis Savva
David Bhella @dbhella.bsky.social · 25/06/2026
We really appreciate the time and work that @orestissavva.bsky.social put into preparing the PreLights article, and his thoughtful questions were a nice avenue for Charlotte to expand on her work. Thanks to BioRxiv for highlighting this resource.
031
Reposted by Orestis Savva
preLights @prelights.bsky.social · 11/06/2026
Cats: the ultimate pets and scientific heroes. 🐱 Studying feline viruses to identify innovative solutions to prevent human infections. #preprint by @cb99-lewis.bsky.social, @dbhella.bsky.social & team #microbiology #preLight by @orestissavva.bsky.social: prelights.biologists.com/highlights/i...
prelights.biologists.com
Inhibition of VP2-mediated entry: a potential antiviral strategy to treat or prevent calicivirus disease - preLights
Cats: the ultimate pets and scientific heroes. Researchers are studying feline viruses to identify innovative solutions to prevent human infections
075
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 12/08/2025
Cryo-EM ligand building using AlphaFold3-like model and molecular dynamics pubmed.ncbi.nlm.nih.gov/40788932/ #cryoEM
044
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 11/08/2025
Cool and collected: Advances in sample preparation for cryo-electron microscopy pubmed.ncbi.nlm.nih.gov/40784122/ #cryoEM
033
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 27/07/2025
Human ribosome interactions reframe neomycin toxicity www.biorxiv.org/content/10.1101/2025.07.22.666027v1 #cryoEM
012
Reposted by Orestis Savva
Martin Pacesa @martinpacesa.bsky.social · 30/06/2025
We have written up a tutorial on how to run BindCraft, how to prepare your input PDB, how to select hotspots, and various other tips and tricks to get the most out of binder design! github.com/martinpacesa...
413755
Reposted by Orestis Savva
RCSB Protein Data Bank @rcsbpdb.bsky.social · 30/06/2025
Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s reach www.nature.com/artic...
nature.com
Freeze frame: cracking molecular motion
Nature - Time-resolved cryo-electron microscopy can resolve protein motion on millisecond or even microsecond timescales, but the need for highly specialized tools and skills limits the method’s...
084
Reposted by Orestis Savva
Chemistry World @chemistryworld.com · 26/06/2025
New research shows that simply changing how a reaction vessel is positioned on a magnetic stirrer can significantly change a reaction's speed and product quality, influencing the reproducibility of results. #ChemSky #ScienceSky #EduSky
chemistryworld.com
Position of flask on magnetic stirrers can drastically affect reproducibility of experiments
Comprehensive examination reveals improper siting of reaction vessels can affect catalyst formation, alter nanoparticle formation and change yields
32612
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 10/06/2025
Structural studies on ribosomes of differentially macrolide-resistant Staphylococcus aureus strains pubmed.ncbi.nlm.nih.gov/40490363/ #cryoEM
042
Reposted by Orestis Savva
Astbury Biostructure Laboratory @astbury-bsl.bsky.social · 02/06/2025
A great read on how flexibility and air–water interface interactions impact SPA cryo-EM data quality! Congratulations @isobelhirst.bsky.social @stemuench.bsky.social @scarfflab.bsky.social and the team!
092
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 02/05/2025
Illuminating ubiquitination mechanisms: How cryo-EM has shed light on Cullin RING E3 ligase function pubmed.ncbi.nlm.nih.gov/40311545/ #cryoEM
021
Reposted by Orestis Savva
Fragment-Screen @fragment-screen.bsky.social · 23/04/2025
Missed any of the Fragment-Screen webinars with @instruct-eric.bsky.social? Take a look at them here, with talks from @ceitec.eu, @ebi.embl.org, IBM Research and FFULisboa! fragmentscreen.org/news-and-eve...
035
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 20/04/2025
Protein structure prediction via deep learning: an in-depth review pubmed.ncbi.nlm.nih.gov/40248099/ #cryoEM
042
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 19/04/2025
Unraveling the proton-sensing mechanisms of G protein-coupled receptors: Insights from cryogenic electron microscopy studies pubmed.ncbi.nlm.nih.gov/40250408/ #cryoEM
021
Reposted by Orestis Savva
Arne Schneuing @rne.bsky.social · 07/03/2025
The code & camera-ready version of our #ICLR2025 paper on "Multi-domain Distribution Learning for De Novo Drug Design" are now available 📚 Paper: openreview.net/forum?id=g3V... 💻 Code: github.com/LPDI-EPFL/Dr... (1/4)
2257
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 22/03/2025
The structural diversity of psychedelic drug actions revealed pubmed.ncbi.nlm.nih.gov/40108183/ #cryoEM
042
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 16/03/2025
Structure-guided design of partial agonists at an opioid receptor pubmed.ncbi.nlm.nih.gov/40082451/ #cryoEM
032
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 26/02/2025
Protein bL38 facilitates incorporation of uL6 during assembly of the 50S subunit in Flavobacterium johnsoniae pubmed.ncbi.nlm.nih.gov/39997215/ #cryoEM
011
Reposted by Orestis Savva
Utrecht Virology Lab @utrechtvirology.bsky.social · 23/02/2025
"Norovirus replication, host interactions and vaccine advances" www.nature.com/articles/s41...
nature.com
Norovirus replication, host interactions and vaccine advances - Nature Reviews Microbiology
In this Review, the authors highlight recent advances in human norovirus biology, including classification, strain-specific differences in cell entry and innate immune responses. They also highlight p...
0245
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 08/02/2025
HflX-mediated drug resistance through ribosome splitting and rRNA disordering in mycobacteria pubmed.ncbi.nlm.nih.gov/39913204/ #cryoEM
012
Reposted by Orestis Savva
Kate Michie @kmichie.bsky.social · 29/11/2024
Beautiful work! 🧬🧶 www.science.org/doi/10.1126/...
science.org
Molecular basis of mRNA delivery to the bacterial ribosome
Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...
1145
Reposted by Orestis Savva
cryoEM papers @cryoempapers.bsky.social · 11/12/2024
The binding of RbgA to a critical 50S assembly intermediate facilitates YphC function in bacterial ribosomal assembly pubmed.ncbi.nlm.nih.gov/39658043/
021
Orestis Savva @orestissavva.bsky.social · 07/12/2024
Apparently, everyone is moving to Blue Sky now...
000