Nonia Pariente @npariente.bsky.social · 4hSo well deserved, with all the caveats that a lot of people contributed to the technology etc, but optogenetics has been nothing short of a revolution 0184
Reposted by Nonia ParienteOnisillos @onisillos.bsky.social · 02/10/2026Although the narrative is shifting to highlight the "increasing share of deaths" attributable to non-communicable diseases, note that "despite the global decline, 7 of the top 10 causes of death in 2023 in low-income countries were communicable diseases". www.who.int/news-room/fa... 21712
Reposted by Nonia ParienteKate Baker @ksbakes.bsky.social · 25/09/2026We have an open Assistant/Associate Professor position in Pathogen Biology at the Department of Genetics - come and join us! 🦠 🧫 🧬https://www.cam.ac.uk/jobs/assistantassociate-professor-in-pathogen-genetics-pc51175cam.ac.ukAssistant/Associate Professor in Pathogen GeneticsApplications are invited for an Assistant or Associate Professorship in Pathogen Genetics to be held in the Department of Genetics. We are searching for a talented individual with a track record of fu... 03970
Reposted by Nonia ParienteYasin Dagdas @plantophagy.bsky.social · 29/09/2026@e3chembio.bsky.social is telling us their efforts in understanding the role of giant E3 ligases in disease set up. #EMBOUbiquitin 031
Nonia Pariente @npariente.bsky.social · 28/09/2026⬇️⬇️ Important tool to identify and track #Dengue virus lineages #ViroSky 🧪 042
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 28/09/2026#TrendingNow | How can we improve research #reproducibility? @kdcobey &co surveyed more than 1,900 biomedical researchers for thoughts on irreproducibility in research results, conducting replication studies, and relevant funding and training #ICYMI #AcademicSky 🧪 plos.io/3ApZJ4Nplos.ioBiomedical researchers’ perspectives on the reproducibility of researchThere is growing interest in the reproducibility of research and ways to enhance transparency. This study uses an international survey of more than 1900 biomedical researchers to reveal the perceived… 062
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 21/09/2026How do the brain's anatomical architecture & functional activity patterns become established during early life? This study of developmental changes in the #brain from perinatal to toddlerhood reveals the organization of networks & #cognitive development @plosbiology.org 🧪 buff.ly/UESbFve 01711
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 21/09/2026#TrendingNow | How and why does #stuttering develop in children? This Unsolved Mystery looks at how genetics, interacting neural hierarchies, social context, and reward circuitry contribute to the many facets of stuttering. #ICYMI #NeuroSky 🧪 buff.ly/kVPTXuAbuff.lyKnowns and unknowns about the neurobiology of stutteringThe origin of stuttering is closely linked to early brain development in children but ultimately unknown. This Unsolved Mystery highlights critical questions that could inspire future research to… 072
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 22/09/2026#TrendingNow | The anatomy of multicellular structures such as #biofilms influences how cells can access resources. This study shows that #bacteria in biofilms divide along oxygen gradients, affecting the physiology and drug susceptibility of biofilm subzones. #ICYMI #MicroSky 🧪 buff.ly/aHITgjpbuff.lyCellular arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilmsCells must access resources to survive, and the anatomy of multicellular structures influences this access. This study shows that bacteria in biofilms divide along oxygen gradients; their end-to-end… 074
Reposted by Nonia ParienteNonia Pariente @npariente.bsky.social · 21/09/2026😎 paper alert Can viral infections reactivate dormant cancer cells? How does inflammation triggered by pathogens (or other stresses) intersect with anticancer immunity? Rincon, de Gregori and cols discuss the processes at this important interface 🧪 ⬇️ 095
Nonia Pariente @npariente.bsky.social · 21/09/2026😎 paper alert Can viral infections reactivate dormant cancer cells? How does inflammation triggered by pathogens (or other stresses) intersect with anticancer immunity? Rincon, de Gregori and cols discuss the processes at this important interface 🧪 ⬇️ 095
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 17/09/2026#Flaviviruses reshape cell membranes to build replication sites, but how are these organized? This study shows that homotypic #membrane tethering driven by host ER protein atlastin-2 is essential for organizing these sites & supporting #viral replication @plosbiology.org 🧪 buff.ly/9MBKCbR 052
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 17/09/2026#TrendingNow | Lighting conditions for laboratory mammals are currently set according to the sensitivity of human vision. This Consensus View defines alternative ‘animal-centric’ metrics and provides guidance for their application. #ICYMI #biomedical #AcademicSky 🧪 buff.ly/hk3IoQKbuff.lyRecommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal researchLighting conditions for laboratory mammals is currently set according to the sensitivity of human vision. This Consensus View defines alternative ‘animal-centric’ metrics and provides guidance for… 052
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 18/09/2026Most #bacterial #immune systems raise an alarm when they sense a #phage. This Primer explores a @plosbiology.org study showing how type II Panoptes reverses this logic by maintaining a quiet signal & sensing infection through its sudden disappearance 🧪 Paper: buff.ly/1ixwg9v Primer: buff.ly/WmnHZBp 132
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 18/09/2026#TrendingNow | This study reveals how the >10,000 different possible amino-acid mutations in hemagglutinin affect cell entry, receptor preference, protein stability and neutralization by antibodies for H5 #influenza, which is a potential pandemic threat. #ICYMI #MicroSky🧪 buff.ly/ojZfSyGbuff.lyDeep mutational scanning of H5 hemagglutinin to inform influenza virus surveillanceH5 influenza is considered a potential pandemic threat. Using deep mutational scanning, this work reveals how the >10,000 different possible amino-acid mutations in hemagglutinin affect cell entry,… 023
Reposted by Nonia ParienteAaron Reichlin-Melnick @reichlinmelnick.bsky.social · 18/09/2026My grandfather, who is 102 and a medical doctor, has told me about the times before polio was cured. Most years, upon returning to school after summer’s break, there would be some children would didn’t make it back to school because of polio. 16637121038
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 16/09/2026#Phages can evade #bacterial #immunity by disrupting #antiviral signals like cA3, triggering the Panoptes defense systems. @mfwhite2.bsky.social &co show that Type II Panoptes detects cA3 loss and activates a CARF-TM effector to disrupt membranes & stop infection @plosbiology.org 🧪 buff.ly/1ixwg9v 1145
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 16/09/2026#TrendingNow | Is cancer is purely a ‘genetic disease’? This Essay delves into cancer omics data that questions the somatic mutation theory and presents theories based on gene regulatory networks and tissue fields that help explain inconsistencies in the data. #ICYMI #cancer 🧪 buff.ly/s49Y8msbuff.lyThe end of the genetic paradigm of cancerGenome sequencing results and single-cell transcriptomics continue to produce findings that challenge the idea that cancer is purely a ‘genetic disease’. This Essay delves into cancer omics data that… 051
Nonia Pariente @npariente.bsky.social · 16/09/2026Happy to get you a couple if you DM or email me (address is in our website) where I would need to post them 220
Nonia Pariente @npariente.bsky.social · 16/09/2026It was me, I think! I felt sorry not to have any extra ones with me 100
Reposted by Nonia ParienteMalcolm White @mfwhite2.bsky.social · 16/09/2026Our paper on type II Panoptes is now published at PLOS Biology with new data on phage escapers - quite a step up in microbiology for our lab, led by Sabine Gruschow. Thanks to @erc.europa.eu for funding dx.plos.org/10.1371/jour... 14628
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 15/09/2026#TrendingNow | Current treatments for #AlzheimersDisease are hampered by limited efficacy, side effects and high costs. This Essay highlights non-invasive sensory stimulation as a promising emerging technology for the treatment of Alzheimer's disease. #ICYMI #NeuroSky 🧪 buff.ly/jYJJu6ubuff.lyInnovations in noninvasive sensory stimulation treatments to combat Alzheimer’s diseaseCurrent treatments for Alzheimer disease are hampered by limited efficacy, side effects and high costs. This Essay highlights non-invasive sensory stimulation as a promising emerging technology for… 072
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 14/09/2026#TrendingNow | There has been an explosion of formulaic research articles, including inappropriate study designs and false discoveries. This study highlights how new unethical research practices using #AI are exploiting the US NHANES resource. #ICYMI #biomedical 🧪 buff.ly/PxKxi6mbuff.lyExplosion of formulaic research articles, including inappropriate study designs and false discoveries, based on the NHANES US national health databaseThe combination of AI and national health databases offers opportunities, but may also be exploited by unethical agents. This study shows that there has been an explosion of formulaic research… 1168
Reposted by Nonia ParientePlantEvolution 🌱🌾 @plantevolution.bsky.social · 14/09/2026Please consider submitting comments on the implementation for genome edited plants in the EU. Reminder: this is not the place for general statements regarding your personal vie of #NGT. Instead, the Commission is asking for input for the development of workable rules. 1612
Reposted by Nonia ParienteInga Songailiene @ingasongailiene.bsky.social · 11/09/2026great stuff! Tried it already 🥼 023
Nonia Pariente @npariente.bsky.social · 14/09/2026Definitely more relaxed, and especiallly for initial submission. Please do not reformat 020
Nonia Pariente @npariente.bsky.social · 13/09/2026That is a bottleneck not addressed in this work. Agreed 000
Reposted by Nonia ParienteDiversify Microbiology @diversifymicro.bsky.social · 11/09/2026UNC Greensboro Department of Biology is hiring for three positions this year including one in microbiology! spartantalent.uncg.edu/postings/35918spartantalent.uncg.eduAssistant Professor MicrobiologyThe Department of Biology at UNC Greensboro (UNCG) seeks an individual with a strong record of accomplishment in microbiology broadly defined for a tenure-track faculty position at the rank of Assista... 05585
Reposted by Nonia ParientePLOS @plos.org · 08/09/2026The first articles have now been published in our new journal, PLOS Ecosystems. These papers bring together open research from multiple disciplines to address the challenges facing our terrestrial, freshwater and marine ecosystems. Read the first articles: buff.ly/8rsP0Z3 01112
Reposted by Nonia ParienteProf Ian Hall @ianhall.bsky.social · 09/09/2026🌊 Kelp forests are estimated to be losing ~1.8% (~11,500 km²) of their area annually. The striking part? The carbon-sink capacity lost from the climate-driven decline is 1,000–10,000× larger than the gains achieved via seaweed restoration, afforestation & farming. journals.plos.org/plosbiology/...journals.plos.orgSeaweed carbon removal cannot keep up with climate-driven lossSeaweed forests are widely viewed as natural climate solutions, yet warming oceans are driving their rapid decline. This Essay reveals that losses are outpacing restoration efforts by orders of magnit... 25946
Reposted by Nonia ParienteCameron Thrash @jcamthrash.bsky.social · 02/09/2026The 100 Diatom Genomes Project journals.plos.org/plosbiology/... #jcampubsjournals.plos.orgThe 100 Diatom Genomes ProjectThis Community Page presents the 100 Diatom Genomes Project, which aims to sequence the genomes and transcriptomes of 100 diatom species across major lineages, life forms and ecological strategies. Th... 0146
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 10/09/2026#Seaweed forests are widely viewed as natural climate solutions, but warming oceans are driving their rapid decline. Karen Filbee-Dexter, @twernberg.bsky.social &co reveal that losses are outpacing restoration efforts by orders of magnitude, raising urgent concerns @plosbiology.org 🧪 buff.ly/C8mfltu 076
Reposted by Nonia ParientePLOS Biology @plosbiology.org · 10/09/2026#TrendingNow | The proportion of studies that successfully translate from animals to humans may be greater than we think. However, the low rate of final regulatory approval indicates potential design flaws of both animal studies and early clinical trials. #ICYMI #biomedical 🧪 buff.ly/XAysMWIjournals.plos.orgAnalysis of animal-to-human translation shows that only 5% of animal-tested therapeutic interventions obtain regulatory approval for human applicationsBased on the analysis of 376 therapies in 54 human diseases, this study shows that, contrary to widespread assertions, the proportion of successful animal-to-human translation may be higher than… 063
Nonia Pariente @npariente.bsky.social · 12/09/2026Experimenting with new models of peer review is essential to move to a future of #publishing that better serves science and researchers ⬇️ DiscoveryStack is an interesting attempt, aiming to separate the assessment of quality & impact @maxkrummel.bsky.social @richardsever.bsky.social 🧪 41411
Nonia Pariente @npariente.bsky.social · 12/09/2026We’re reposting some trending articles from our recent past, for those that may have missed them. Below is an excellent resource from @aharms485.bsky.social lab expanding the BASEL phage collection 🧪#ViroSky #Microsky 0145
Reposted by Nonia ParienteFrancesca Cesari @francesari.bsky.social · 09/09/2026Tested in female mice only, semaglutide given late in life improved physical, metabolic and cognitive function and extended lifespan. The mechanisms partly overlap with calorie restriction, but human ageing effects are untested. 🧪 www.nature.com/articles/s41...nature.comLate-life semaglutide treatment slows ageing and extends lifespan in female mice - NatureSemaglutide treatment for 3 months in female mice improved physiological function, attenuated hallmarks of ageing and modulated nutrient sensors and conserved genetic regulators of ageing. 096
Reposted by Nonia ParienteAntonio Martínez Ron @aberron.bsky.social · 06/09/2026La candidez y permisividad con la que las democracias liberales han tratado el fascismo las vamos a pagar muy caras. 19636316
Nonia Pariente @npariente.bsky.social · 04/09/2026Whatever could go wrong in this scenario, I wonder 010
Reposted by Nonia ParienteThomas Mock @thomasmock.bsky.social · 04/09/2026Thanks Nonia! Indeed, we aim to go beyond 100 diatom genomes based on a global community effort. Another goal is to link genetic variants with traits for integrative diatom research. This helps to address questions from the origin of evolutionary innovations to ecology and biotechnology. 011
Nonia Pariente @npariente.bsky.social · 04/09/2026After the wildly successful 1000 fungal genomes project... make way for the 100 #diatom genomes project (to go beyond 100 eventually) The 100DGP portal provides users with access to all genome assemblies, transcriptomes and annotations (phycocosm.jgi.doe.gov/100_Diatom_G...) @plosbiology.org 🧪phycocosm.jgi.doe.gov 1174
Reposted by Nonia ParienteThomas Mock @thomasmock.bsky.social · 01/09/2026On behalf of 108 colleagues and friends from 11 countries, thrilled to share the first paper from our 100 #Diatom Genomes Project (100DGP). Just out @plosbiology.org | @norwichmicro.bsky.social | @ueaenv.bsky.social | @jgi.doe.gov doi.org/10.1371/jour...doi.orgThe 100 Diatom Genomes ProjectThis Community Page presents the 100 Diatom Genomes Project, which aims to sequence the genomes and transcriptomes of 100 diatom species across major lineages, life forms and ecological strategies. Th... 09437
Nonia Pariente @npariente.bsky.social · 03/09/2026Enhorabuena! A topic very close to my heart. Good choice by the ERC For all your publishing needs, do consider @plosbiology.org 😝 110
Reposted by Nonia ParienteNonia Pariente @npariente.bsky.social · 01/09/2026Timely issue given situations such as the one below - women's basic physiology is far from understood, chronically underfunded and understudied. This needs to change to improve health outcomes. @plosbiology.org calls for more funding & more exposure of basic research in this field plos.io/4ckiAOuplos.ioBasic research into Women’s Health should be a priority for allDespite recent progress in clinical research into Women’s Health, basic research is still lagging behind. This Editorial calls for a renewed focus on basic physiology research into both sexes to close the gap. 1126
Reposted by Nonia ParienteNonia Pariente @npariente.bsky.social · 01/09/2026This is an issue particularly close to my heart - women's basic physiology is far from understood, chronically underfunded and understudied. This needs to change to improve health outcomes. Here @plosbiology.org calls for more funding for basic research in this area & more exposure of the results 🧪 22320
Reposted by Nonia ParienteU. Nomi @uniofnomi.bsky.social · 02/09/2026The degree of bias is an embarrassment for #science. Example: T. vaginalis, the most prevalent nonviral STI that disproportionately affects women everywhere. It's caused by a #parasite that's easy to see & recognize under a microscope. So why is it "neglected"? pmc.ncbi.nlm.nih.gov/articles/PMC...pmc.ncbi.nlm.nih.govTrichomoniasis: The “Neglected” Sexually Transmitted Disease 001
Nonia Pariente @npariente.bsky.social · 01/09/2026Timely issue given situations such as the one below - women's basic physiology is far from understood, chronically underfunded and understudied. This needs to change to improve health outcomes. @plosbiology.org calls for more funding & more exposure of basic research in this field plos.io/4ckiAOuplos.ioBasic research into Women’s Health should be a priority for allDespite recent progress in clinical research into Women’s Health, basic research is still lagging behind. This Editorial calls for a renewed focus on basic physiology research into both sexes to close the gap. 1126
Nonia Pariente @npariente.bsky.social · 01/09/2026This is an issue particularly close to my heart - women's basic physiology is far from understood, chronically underfunded and understudied. This needs to change to improve health outcomes. Here @plosbiology.org calls for more funding for basic research in this area & more exposure of the results 🧪 22320