Living cells organise biochemical reactions through specialised internal compartments called organelles. This PhD project will engineer synthetic organelles to enhance the capabilities of future gener...

Langstein-Skora, Schmid, Huth et al. propose that intrinsically disordered region functionality can be driven by the interplay between linear binding motifs and contextual chemical characteristics suc...

The tools of structural biology have undergone remarkable advances in the past decade. These include new computational and experimental approaches tha…

Intrinsically disordered regions (IDRs) in proteins play essential roles in cellular function. A growing body of work has shown that IDRs often interact with partners in a manner that does not depend ...

The localization of biomolecular condensates to intracellular membrane surfaces has emerged as an important feature of sub-cellular organization. In this work,

Cells chemically isolate molecules in compartments to both facilitate and regulate their interactions. In addition to membrane-encapsulated compartmen…

Please join us in-person and online for the annual Burton Lecture at King's College London with Professor Charlotte Williams OBE FRS.

Biomolecular condensates are non-stochiometric assemblies that organize cellular matter in space and time. Despite much work, many questions remain regarding what determines the recruitment and exclus...

Melvyn Bragg and guests discuss ideas about where life may begin in the universe and how.