iiinova — where your digital self keeps evolving

Reposted by Nicole Mather

Biohub @biohub.org · 29/04/2026

Today we're announcing the Virtual Biology Initiative—a major new commitment to build the data foundation biology needs to power the next generation of AI models. Next-gen imaging. Molecular engineering tools. Open data infrastructure for the entire scientific community. Read more: bit.ly/3ONTkHO

bit.ly

Biohub launches the Virtual Biology Initiative

A $500M commitment to galvanize a global, open-data effort to build predictive models of the human cell.

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Reposted by Nicole Mather

UK Biobank @ukbiobank.ac.uk · 10/02/2026

✅ The UK Government has today granted access to half a million UK Biobank participants' coded GP data for health research. This change will dramatically increase the power of UK Biobank's dataset to advance the diagnosis, treatment and management of conditions handled by GPs.

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Reposted by Nicole Mather

Cell and Gene Therapy Catapult @cgtcatapult.bsky.social · 22/07/2025

In the first investment from the CGT Catapult as part of the Cross-Catapult Investment Pilot, Spliceor has received funding to accelerate the pre-clinical development of its trans-splicing #GeneTherapy platform for liver cancer. Learn more: lnkd.in/e4h9xNkQ @catapultnetwork.bsky.social

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Reposted by Nicole Mather

Cell and Gene Therapy Catapult @cgtcatapult.bsky.social · 12/06/2025

@nicolemather.bsky.social delivered a powerful talk on how AI & digital technologies can transform ATMP production at our CGT Catapult & Alliance for Regenerative Medicine Industrialisation workshop today! Key areas included: data standardisation, platform scale out & flexible automation.

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Reposted by Nicole Mather

Cell and Gene Therapy Catapult @cgtcatapult.bsky.social · 28/05/2025

Following the ATI North event last month, we reflect on key takeaways from the “Digitally Driven” panel chaired by @nicolemather.bsky.social. Discussion explored how digital tools are helping to reduce the cost of #ATMPs and unlock patient-centric therapies. Read the blog: ow.ly/u0Fy50VZQQC

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Nicole Mather @nicolemather.bsky.social · 10/03/2025

Looking forward to speaking at #ReWired2025 about how #AI is already transforming #NHS #Productivity away from the front line, reducing waiting lists & time taken for clinical coding & HR support. Talking about how to #spread & #scale this approach nationally so patients and staff can benefit more

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Reposted by Nicole Mather

Wellcome Sanger Institute @sangerinstitute.bsky.social · 04/03/2025

By mapping how thousands of inherited genetic changes play a role in developing chronic conditions, researchers have uncovered new connections between our genes and health 🧬 www.sanger.ac.uk/news_item/tr...

sanger.ac.uk

Translating genetic changes into future health impact

New resource helps bridge the gap between identifying genetic changes linked to health conditions and understanding how these changes impact biological processes.

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Reposted by Nicole Mather

Eric Topol @erictopol.bsky.social · 25/02/2025

A treasure chest of all of our immune system exposures and responses is hiding in our B and T cell receptors. Now that's being decoded to make diagnoses. erictopol.substack.com/p/the-first-...

erictopol.substack.com

The First Diagnostic Immunome

A Big Step Forward By Sequencing B and T Cell Receptors Plus A.I.

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Reposted by Nicole Mather

Eric Topol @erictopol.bsky.social · 04/02/2025

New: The largest medical A.I. randomized controlled trial yet performed, enrolling >100,000 women undergoing mammography screening The use of AI led to 29% higher detection of cancer, no increase of false positives, and reduced workload compared with radiologists w/o AI thelancet.com/journals/lan...

thelancet.com

Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, ...

The findings suggest that AI contributes to the early detection of clinically relevant breast cancer and reduces screen-reading workload without increasing false positives.

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Reposted by Nicole Mather

Ethan Mollick @emollick.bsky.social · 02/02/2025

Been waiting for someone to test this and see if it works - can multiple AI agents fact-checking each other reduce hallucinations? The answer appears to be yes - using 3 agents with a structured review process reduced hallucination scores by 96% across 310 test cases. arxiv.org/pdf/2501.13946

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Nicole Mather @nicolemather.bsky.social · 29/01/2025

Great to meet so many folks at #FOG2025 Festival of Genomics today to talk about super interesting stuff our research teams are doing with biomedical foundation models in omics, agentic workflows in labs and pB storage solutions. Booth 81 if you are there tomorrow?

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Reposted by Nicole Mather

Sjors Scheres @sjorsscheres.bsky.social · 27/01/2025

We have an exciting opportunity for a new independent group leader with an interest in structural/molecular biology and machine learning to join our Division of Structural Studies at the @mrclmb.bsky.social! 🥳 Re-posts appreciated. www.nature.com/naturecareer...

nature.com

Research Group Leader Tenure Track - Structural Studies - LMB 2549 - Cambridgeshire job with MRC Laboratory of Molecular Biology | 12835196

Research Group Leader Tenure Track Starting Salary £65,940 to £74,448 per annum MRC Laboratory of Molecular Biology, Cambridge, UK

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Reposted by Nicole Mather

Eric Topol @erictopol.bsky.social · 10/01/2025

Something you don't see every day! Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins www.cell.com/cell/fulltex... open-access

The cover image portrays a human composed of proteins who is examining their health status (represented by the ECG monitoring interface) with the assistance of artificial intelligence (represented by the chip and binary codes).

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Reposted by Nicole Mather

Eric Topol @erictopol.bsky.social · 09/01/2025

How the brain gets rid of its chemical waste through the glymphatics during sleep, via blood vessel oscillations, regulated by norepinephrine. Impeded by Ambien! www.cell.com/cell/abstrac... www.science.org/content/arti...

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Reposted by Nicole Mather

Hetan Shah @hetanshah.bsky.social · 06/01/2025

I'm honoured to have been asked to give this year's @healthfoundation.bsky.social annual REAL Challenge lecture - on the theme of AI and health. Thursday 13th Feb in person / online. You can register here and please do share with any networks that may be interested www.health.org.uk/events/hype-...

health.org.uk

Hype, hallucination, hope – what might AI mean for our health?

In our fifth REAL Challenge annual lecture, Hetan Shah will warn of the risk of rushing breathlessly to unleash technology. He will explore how policymakers can navigate the hype and critically assess...

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Reposted by Nicole Mather

Hetan Shah @hetanshah.bsky.social · 10/12/2024

The Department for Energy Security and Net Zero is looking for members for a new Science and Technology Advisory Council and are looking for expertise which includes economics, social science and statistics. £350 a day. 12 vacancies apply-for-public-appointment.service.gov.uk/roles/8465

apply-for-public-appointment.service.gov.uk

Appointment details – Department for Energy Security and Net Zero - Science and Technology Advisory Council (STAC) - Members – Apply for a public appointment – GOV.UK GOV.UK

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Reposted by Nicole Mather

Emma Barrett @crimepsychblog.bsky.social · 06/12/2024

Ofcom looking for NEDs to join new Advisory Committee on Disinformation & Misinformation. 7-10 days (paid) per year. Closes 13 Jan Good opportunity for researchers with expertise in "disinformation, misinformation, foreign interference or related areas" ofcom.wd3.myworkdayjobs.com/en-US/Ofcom_...

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Reposted by Nicole Mather

Drew Armstrong @drewsnews.bsky.social · 04/12/2024

Lilly released it's head-to-head with Wegovy today and it appears to have a meaningful edge on long-term weight loss (handy chart from Liz Cairns)

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Nicole Mather @nicolemather.bsky.social · 03/12/2024

Today we welcomed #NHS leaders to our #IBM office along with #HSJ to discuss how digital will reshape healthcare in future.

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Nicole Mather @nicolemather.bsky.social · 26/11/2024

The way science is being done has been transformed by AI. Thought provoking essay from the @deep-mind.bsky.social team open.substack.com/pub/aipolicy... #GeneSky #DataScience

open.substack.com

A new golden age of discovery

Seizing the AI for Science opportunity

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Nicole Mather @nicolemather.bsky.social · 26/11/2024

Scaling up cell & gene therapies and reducing cost of goods so many more patients can benefit is urgent. I spoke with Matthew Durdy, our CEO at @cgtcatapult.bsky.social about how tech can help. Thank you to #CellTherapiesIntegrates for the invite #automation #predictiveanalytics #digitaltwins #data

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Nicole Mather @nicolemather.bsky.social · 24/11/2024

Weekend reading.. Scale proteomics gives insights into disease progression, aging and related druggable targets. #ProteomicSky #GeneSky

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Nicole Mather @nicolemather.bsky.social · 22/11/2024

Delighted to contribute #HumanCellAtlas pics to #FluorescenceFriday. Long time since I took some myself but proud of the #WellcomeSanger contribution here - shows human thymus @mehurles.bsky.social

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Reposted by Nicole Mather

Honey de G @girlnextshore.bsky.social · 21/11/2024

Wes Streeting comes in as a surprise speaker at the #HSJAwards. He’s “only been in office for four Liz Trusses” but received warmly amidst an audience of 1700 amazing health and social care champions.

Wes Streeting speaking at the HSJ Awards

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Reposted by Nicole Mather

Kashif Pirzada, MD @kashprime.bsky.social · 21/11/2024

A women-led team of 20, working remotely, is showing up a trillion dollar megacorp. Truly inspiring.

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Reposted by Nicole Mather

Eric Topol @erictopol.bsky.social · 20/11/2024

A big day of output for the Human Cell Atlas, a global collaborative project with 100 countries to understand our ~37 trillion cells A Wikipedia of our cells, a "remarkable achievement" nature.com/articles/d41... nature.com/immersive/d4...

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Reposted by Nicole Mather

Matthew Freeman @mjafreeman.bsky.social · 19/11/2024

Here’s my spreadsheet of starter packs (>80!) related to broadly ‘mechanistic biology’ plus some intriguing extras Complete with collective nouns I’ve been tracking these but now can’t keep up Hope it’s helpful 2/2 docs.google.com/spreadsheets...

docs.google.com

@mjafreeman.bsky.social's BlueSky starter packs for 'mechanistic' biologists

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