Nature Reviews Endocrinology, Published online: 07 October 2026; doi:10.1038/s41574-026-01308-yHere, the authors explore the potential of using deep human phenotype data from large cohort studies and advances in omics technologies and wearables to provide personalized nutrition guidance and improve the prevention and management of metabolic disorders. They discuss how these approaches could be integrated into broader clinical practice and describe the challenges that must be overcome.

Nature Reviews Endocrinology, Published online: 07 October 2026; doi:10.1038/s41574-026-01309-xThis Review outlines the latest understanding of advanced glycation end product (AGE) formation, AGE receptors, signal transduction mediated by AGEs, the roles of AGEs in the pathogenesis of diabetic complications and the potential methods to target AGEs to treat chronic diseases, such as diabetes mellitus and its complications.

Nature Reviews Endocrinology, Published online: 07 October 2026; doi:10.1038/s41574-026-01308-yHere, the authors explore the potential of using deep human phenotype data from large cohort studies and advances in omics technologies and wearables to provide personalized nutrition guidance and improve the prevention and management of metabolic disorders. They discuss how these approaches could be integrated into broader clinical practice and describe the challenges that must be overcome.

Nature Reviews Endocrinology, Published online: 07 October 2026; doi:10.1038/s41574-026-01309-xThis Review outlines the latest understanding of advanced glycation end product (AGE) formation, AGE receptors, signal transduction mediated by AGEs, the roles of AGEs in the pathogenesis of diabetic complications and the potential methods to target AGEs to treat chronic diseases, such as diabetes mellitus and its complications.

The 2026 Nobel Prize in Physiology or Medicine has been awarded jointly to Karl Deisseroth, Peter Hegemann and Georg Nagel “for discoveries leading to ...

Nature Reviews Endocrinology, Published online: 02 October 2026; doi:10.1038/s41574-026-01311-3As highly potent weight loss drugs become available, interest grows in whether repeated cycles of weight loss and regain can exacerbate obesity. We argue that weight cycling might contribute to the development of obesity in susceptible lean individuals but seems to have little effect on the progression of obesity and its complications.

Nature Reviews Endocrinology, Published online: 02 October 2026; doi:10.1038/s41574-026-01311-3As highly potent weight loss drugs become available, interest grows in whether repeated cycles of weight loss and regain can exacerbate obesity. We argue that weight cycling might contribute to the development of obesity in susceptible lean individuals but seems to have little effect on the progression of obesity and its complications.

Nature Reviews Endocrinology, Published online: 25 September 2026; doi:10.1038/s41574-026-01310-4Adipocyte-derived oxylipin suppresses breast cancer growth

Nature Reviews Endocrinology, Published online: 25 September 2026; doi:10.1038/s41574-026-01310-4Adipocyte-derived oxylipin suppresses breast cancer growth

Nature Reviews Endocrinology, Published online: 23 September 2026; doi:10.1038/s41574-026-01303-3Silver–Russell syndrome (SRS) is a genomic imprinting disorder associated with prenatal and postnatal growth restriction, and has specific management requirements. This international Consensus Statement provides updated guidance on the diagnosis and life-long management of patients with SRS.

Nature Reviews Endocrinology, Published online: 21 September 2026; doi:10.1038/s41574-026-01302-4Cachexia is a systemic condition of progressive weight loss and muscle and adipose tissue wasting, often seen in cancer and associated with poor prognosis. This Review explores the connection between circulating signalling factors and the brain in the development of cachexia and argues for the importance of pathways within the brain as both drivers of key features of cancer cachexia and promising therapeutic targets.

Nature Reviews Endocrinology, Published online: 23 September 2026; doi:10.1038/s41574-026-01303-3Silver–Russell syndrome (SRS) is a genomic imprinting disorder associated with prenatal and postnatal growth restriction, and has specific management requirements. This international Consensus Statement provides updated guidance on the diagnosis and life-long management of patients with SRS.

Nature Reviews Endocrinology, Published online: 21 September 2026; doi:10.1038/s41574-026-01302-4Cachexia is a systemic condition of progressive weight loss and muscle and adipose tissue wasting, often seen in cancer and associated with poor prognosis. This Review explores the connection between circulating signalling factors and the brain in the development of cachexia and argues for the importance of pathways within the brain as both drivers of key features of cancer cachexia and promising therapeutic targets.

Nature Reviews Endocrinology, Published online: 18 September 2026; doi:10.1038/s41574-026-01301-5Many places in the Middle East and North Africa (MENA) region are undergoing changes in dietary patterns that affect the prevalence of obesity and type 2 diabetes mellitus. In this Review, the authors discuss the role of these nutrition transitions and other related factors in the epidemiology of these diseases across the MENA region.

Nature Reviews Endocrinology, Published online: 18 September 2026; doi:10.1038/s41574-026-01301-5Many places in the Middle East and North Africa (MENA) region are undergoing changes in dietary patterns that affect the prevalence of obesity and type 2 diabetes mellitus. In this Review, the authors discuss the role of these nutrition transitions and other related factors in the epidemiology of these diseases across the MENA region.

Nature Reviews Endocrinology, Published online: 15 September 2026; doi:10.1038/s41574-026-01307-zMonitoring corticosteroid levels in primary aldosteronism

Nature Reviews Endocrinology - Monitoring corticosteroid levels in primary aldosteronism

Nature Reviews Endocrinology, Published online: 15 September 2026; doi:10.1038/s41574-026-01307-zMonitoring corticosteroid levels in primary aldosteronism

Nature Reviews Endocrinology, Published online: 10 September 2026; doi:10.1038/s41574-026-01304-2UCP1 gets a transport mechanism and a challenge

Nature Reviews Endocrinology, Published online: 10 September 2026; doi:10.1038/s41574-026-01306-0High-fat diet promotes tumour formation in the epithelium

Nature Reviews Endocrinology, Published online: 10 September 2026; doi:10.1038/s41574-026-01304-2UCP1 gets a transport mechanism and a challenge

Nature Reviews Endocrinology, Published online: 10 September 2026; doi:10.1038/s41574-026-01306-0High-fat diet promotes tumour formation in the epithelium

Nature Reviews Endocrinology, Published online: 07 September 2026; doi:10.1038/s41574-026-01305-1Adjusting α-cell metabolism induces β-cell features

Nature Reviews Endocrinology, Published online: 07 September 2026; doi:10.1038/s41574-026-01305-1Adjusting α-cell metabolism induces β-cell features

Nature Reviews Endocrinology, Published online: 04 September 2026; doi:10.1038/s41574-026-01295-0In this Review, the authors summarize current knowledge of the diverse range of human primary β cell phenotypes, describe the progress and challenges in making stem cell-derived β cells (SCβ cells) to closely mimic these phenotypes, and offer thoughts on combining new and established technologies to study functional maturity as an important path towards improving SCβ cell functionality.

Nature Reviews Endocrinology, Published online: 04 September 2026; doi:10.1038/s41574-026-01295-0In this Review, the authors summarize current knowledge of the diverse range of human primary β cell phenotypes, describe the progress and challenges in making stem cell-derived β cells (SCβ cells) to closely mimic these phenotypes, and offer thoughts on combining new and established technologies to study functional maturity as an important path towards improving SCβ cell functionality.

Nature Reviews Endocrinology, Published online: 01 September 2026; doi:10.1038/s41574-026-01300-6CheckCausesObesity.com (CCO) is a science-based screening and monitoring tool, developed by multidisciplinary experts and consistent with international guidelines. CCO systematically screens for potential obesity causes and contributing factors across seven categories, including lifestyle and medical factors, alongside selected comorbidities as well as anthropometric, demographic and socioeconomic characteristics. CCO supports individualized assessment, treatment and population-level monitoring.

Nature Reviews Endocrinology, Published online: 01 September 2026; doi:10.1038/s41574-026-01300-6CheckCausesObesity.com (CCO) is a science-based screening and monitoring tool, developed by multidisciplinary experts and consistent with international guidelines. CCO systematically screens for potential obesity causes and contributing factors across seven categories, including lifestyle and medical factors, alongside selected comorbidities as well as anthropometric, demographic and socioeconomic characteristics. CCO supports individualized assessment, treatment and population-level monitoring.

Nature Reviews Endocrinology, Published online: 26 August 2026; doi:10.1038/s41574-026-01299-wAt the Bone Research Society Annual Meeting 2026