Nathalie Percie du Sert @nathalie-pds.bsky.social · 23/07/2026🎉 The DRIVER recommendations are out 🎉 A fantastic milestone that has been years in the making and a very useful resource for an researcher running in vitro studies 010
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 18/12/2025Developed in direct response to NC3Rs recommendations, new guidance from the World Health Organisation (@who.int) encourages manufacturers and regulators to replace or remove animal-based quality control methods for vaccines and biologics: nc3rs.org.uk/news/new-who...nc3rs.org.ukNew WHO guidelines on non-animal tests for quality control of biologicsDeveloped in direct response to NC3Rs recommendations, new guidance supports manufacturers and regulators to transition to non-animal testing strategies. 051
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 04/08/2025Looking for support to teach experimental design? Join our online workshop with @ukrepro.bsky.social on using the Experimental Design Assistant (EDA) to plan rigorous, reproducible animal studies. 📅 13 November, 10.00 – 16.00 (GMT) ❗ Registration closes: 17 September 👉 nc3rs.org.uk/events/ukrn-... 012
Reposted by Nathalie Percie du SertCathy Abbott @cathyabbott.bsky.social · 23/07/2025At the @nc3rs.bsky.social Prize ceremony and hearing about YCharOS- stonkingly high percentage of commercial antibodies don't work in applications for which they are recommended 😬 131
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 16/07/2025ARRIVE 2.0 turns five! Since we launched our updated guidelines in July 2020, we have developed a suite of resources to embed transparency and reproducibility throughout the research lifecycle, from planning to peer review: arriveguidelines.org/resources 133
Nathalie Percie du Sert @nathalie-pds.bsky.social · 09/06/2025So glad to be back in Hong Kong! 🇭🇰 Now let the marathon week begin, we will be presenting seven @nc3rs.bsky.social talks and workshops over four days. I’m especially looking forward to the HKLASS symposium hklass.org 031
Reposted by Nathalie Percie du SertaRukon @arukon0.bsky.social · 06/06/2025📢 Free seminar by @bihatcharite.bsky.social on 𝐉𝐮𝐧𝐞 𝟏𝟕! Dr. Nikki Osborne ( @rrr-research.bsky.social) & Dr. @nathalie-pds.bsky.social (@nc3rs.bsky.social) will share tools for responsible & robust preclinical research. 🔗 bihealth.org/de/translati... #OpenScience #NC3Rs #PreclinicalResearch 032
Reposted by Nathalie Percie du SertMelanie Mitchell @melaniemitchell.bsky.social · 04/06/2025Amazing account of ChatGPT's sycophancy and confabulation on steroids. amandaguinzburg.substack.com/p/diabolus-e...amandaguinzburg.substack.comDiabolus Ex MachinaThis Is Not An Essay 1626584
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 05/06/2025Great to see this publication optimising a hydrogel-based model of cartilage. This approach has the potential to become a scalable platform to investigate biomechanical responses and replace mice in studies of musculoskeletal disease progression and ageing. Learn more: nc3rs.org.uk/our-portfoli... 022
Reposted by Nathalie Percie du SertMark A. Hanson @hansonmark.bsky.social · 03/06/2025URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry. 4225253
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 23/04/2025SURVEY: New approach methodologies in safety assessment Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli... 112
Reposted by Nathalie Percie du SertaRukon @arukon0.bsky.social · 09/05/2025🔬 Transparent animal research is ethical, reproducible, and credible. Want to improve your lab's practices? Follow this 🧵 on the 10 essentials from the 𝐀𝐑𝐑𝐈𝐕𝐄 𝐆𝐮𝐢𝐝𝐞𝐥𝐢𝐧𝐞𝐬 #AnimalResearch #Transparency #ARRIVEguidelines #aRukon 113
Reposted by Nathalie Percie du SertFrank Norman @franknorman.bsky.social · 29/04/2025This is a really good explainer about sex, gender and biology. It gives a clear account of the complexity and richness of differences. 122
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 07/01/2025💡 If you are an educator, science communicator or researcher involved in public engagement, this card game from @comeflywithjo.bsky.social can help you talk about how scientists choose the right biological model for their experiments and options to replace animal use. 1106
Reposted by Nathalie Percie du SertBrian Nosek @briannosek.bsky.social · 10/04/2025"Estimating the replicability of Brazilian biomedical science" For 97 replications of 47 original experiments, 94% of replications were smaller effects than originals, and success rates ranged from 13% to 45% depending on the criterion. Incredible effort! Paper: www.biorxiv.org/content/10.1... 13413
Reposted by Nathalie Percie du SertMic Wright @brokenbottleboy.bsky.social · 04/04/2025NEW | Analysing a story about an academic and smartphone bans… THE ANATOMY OF A SMEAR Comparing two news stories about an academic's view on school smartphone bans reveals just how easy it is to twist the narrative. brokenbottleboy.substack.com/p/4-the-anat...brokenbottleboy.substack.com4. The anatomy of a smearComparing two news stories about an academic's view on school smartphone bans reveals just how easy it is to twist the narrative. 03019
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 02/04/2025The EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) have joined two of our CRACK IT projects as Challenge Partners, bringing their experience in validating new approach methodologies to help bridge the gap between innovation and market adoption: nc3rs.org.uk/news/eurl-ec... 023
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 28/03/2025Register for our NAMs Network symposium to connect with developers and end-users of new approach methodologies and join the discussion about reducing the reliance on animals for toxicity testing. 🗓️ Thursday 1 May, 9.30 – 17.00 📍 London, UK 👉 nc3rs.org.uk/events/nc3rs... 133
Reposted by Nathalie Percie du SertGerman Reproducibility Network @germanrepro.bsky.social · 14/03/2025🔬✨ Interested in research transparency & reproducibility? Join the Meta-Science Summer School: design & launch a meta-research study! ➡️ Co-org. @germanrepro.bsky.social 📅 Date: 15-20 June 2025; apply by March 21! 🔗 www.bihealth.org/en/notices/m... #OpenScience #Reproducibility #MetaResearch (lmf) 034
Reposted by Nathalie Percie du SertAdriana Guatame-García @adriguatame.bsky.social · 06/03/2025A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: “Systematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.” Absurd we still need to go through this 🧪👩🔬 12365112319
Reposted by Nathalie Percie du SertEd 🇨🇦👊🔥 @shored.eurosky.social · 02/03/2025dnschecker.org#A/pubmed.ncb... They're removing it from DNS. You can currently get to it using the IP address 34.107.134.59 (add it to your hosts file or local DNS server), but like with USAID it's probably just a matter of time until it's gone unless they're forced to restore it. #pubmeddnschecker.orgDNS Checker - DNS Check Propagation ToolCheck DNS Propagation worldwide. DNS Checker provides name server propagation check instantly. Changed nameservers so do a DNS lookup and check if DNS and nameservers have propagated. 255
Nathalie Percie du Sert @nathalie-pds.bsky.social · 02/03/2025Pubmed is currently still working for me but not sure how long this will hold. Here is @hildabast.bsky.social ‘s blog post on what to do if Pubmed becomes unreliable absolutelymaybe.plos.org/2025/02/14/w...absolutelymaybe.plos.orgWhat if We Can't Rely on PubMed? - Absolutely MaybePubMed is incredibly reliable. And a lot depends on it. It’s an ecosystem built around MEDLINE, the steady feed of new publications… 061
Reposted by Nathalie Percie du SertAltmetric @altmetric.com · 16/02/2025THREAD Things that didn't make the news that will likely change our lives for the better The news is not an accurate reflection of the world. Good news doesn't get reported as much. Here are the wonderful things researchers have achieved recently. 1/24 2197121
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 12/02/2025If your research focuses on infection or immunity join us in two weeks to stay updated on non-animal approaches in the field, including organoids, human cell-based assays and virtual twins. 🦠 Register for the webinar: nc3rs.org.uk/events/non-a... 📅 Wednesday 26 February, 13.00 (GMT)/14.00 (CET) 042
Reposted by Nathalie Percie du SertABandrowski @abandrowski.bsky.social · 10/02/2025#LoveMethods25 is coming in two weeks. 🔬 Love Methods Week 2025 – Putting Methods like #RRID in the Spotlight! ❤️ ✅ Document your methods with precision – to maximize reusability, transparency, and visibility ➡ Choose from 17 different session and register here: www.bihealth.org/de/aktuell/l...bihealth.orgLove Methods Week - Aktuelles - BIH at CharitéIn dieser Woche werden mehrere Workshops und Seminare rund um das Thema Reproduzierbarkeit von Methoden angeboten. (In Englisch) 033
Reposted by Nathalie Percie du SertStephen Curry @scurry.bsky.social · 11/02/2025An open letter to the President of the @royalsociety.org – time to stand up for your values. occamstypewriter.org/scurry/2025/...occamstypewriter.orgAn open letter to the President of the Royal Society – time to stand up for your values | Reciprocal Space 7332170
Reposted by Nathalie Percie du SertUK Reproducibility Network @ukrepro.bsky.social · 24/01/2025To help you connect with us and each other, we've created a Starter Pack of UK Reproducibility Network people and affiliated organisation on BlueSky: #AcademicSky #OpenResearch #Research 063
Reposted by Nathalie Percie du SertDr. Wendy Bohon @drwendyrocks.bsky.social · 05/02/2025NASA did a feature on me last year. It was up this weekend but now when you click on the link you get a 404 message. 11732481795
Reposted by Nathalie Percie du SertReproducibility for Everyone (R4E) @repro4everyone.bsky.social · 04/02/2025I#LoveMethodsWeek25 is happening this year! We are hosting a workshop! Sign up for our workshop here: buff.ly/40SG1Jn Check out other events here: buff.ly/40Axc5u 041
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 21/01/2025⏰ The CRACK IT open call for 3Rs Challenges closes on Monday 10 February. If your organisation is facing a scientific or research challenge that could be solved with a 3Rs approach, get in touch to discuss and submit your idea to sponsor a Challenge. 💡 Find out more: nc3rs.org.uk/crackit/news... 033
Reposted by Nathalie Percie du SertMichel Dubois @ejsmdubois.bsky.social · 31/01/2025"Most institutions judge their own researchers, leading to major conflicts of interest, and whistleblowers are often the ones who suffer the most" - interesting interview from Noémie Berroir (TheMetaNews) with @deevybee.bsky.social themeta.news/dorothy-bish...themeta.newsDorothy Bishop : « J’ai démissionné quand j’ai compris que la Royal Society ne ferait rien contre Musk » — TheMetaNewsAu mois de novembre 2024, vous avez quitté la Royal Society, l’équivalent britannique de l’Académie des sciences française. Le regrettez-vous ? Aucunement, je suis encore plus satisfaite de ma décisio... 0104
Nathalie Percie du Sert @nathalie-pds.bsky.social · 30/01/2025This is very exciting, brilliant to see all these great initiatives and organisations brought together in one journal! lifecyclejournal.org/evaluation-s...lifecyclejournal.orgEvaluation Services | Lifecycle Journal 041
Reposted by Nathalie Percie du SertCathy Abbott @cathyabbott.bsky.social · 18/12/2024Really nice blog post on teaching experimental design to undergrads using the @nc3rs.bsky.social EDA - sounds like a really imaginative way of using a great tool! nc3rs.org.uk/news/teachin...nc3rs.org.ukTeaching experimental design with the EDAHear how lecturers at the University of Nottingham are using the Experimental Design Assistant (EDA) as an engaging and practical way to teach experimental design. 2132
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 11/12/2024As we celebrate 20 years of the NC3Rs this year, 20,000 scientists are now using the Experimental Design Assistant (EDA) to design more rigorous in vivo studies and improve the reproducibility of animal research. Why not join them? eda.nc3rs.org.uk 132
Reposted by Nathalie Percie du SertNC3Rs @nc3rs.bsky.social · 09/12/2024Our Experimental Design Assistant tool helps researchers at any level design robust in vivo experiments. We have updated the report generated by the system to include all the methodological information required in the ARRIVE Essential 10 checklist: eda.nc3rs.org.uk/experimental... 184
Reposted by Nathalie Percie du SertKate Ellacott @neuroendo.bsky.social · 20/11/2024We developed a simple mouse glucose tolerance test protocol for diabetes research with voluntary oral glucose dosing instead of gavage. More physiological/aligned to the human test & better for animal welfare 👇🏻 www.biorxiv.org/content/10.1... Please DM for detailed info or to arrange a chatbiorxiv.orgValidation of a refined protocol for mouse oral glucose tolerance testing without gavageA glucose tolerance test (GTT) is routinely used to assess glucose homeostasis in clinical settings and in preclinical research studies using rodent models. The procedure assesses the ability of the b... 03812
