Reposted by Jo Sharpe
We are pleased that our article on Ataxin-2 and the integrated stress response in C9orf72 ALS/FTD is finally published in full. A lot of hard work from members of the lab, including @comeflywithjo.bsky.social, and our collaborators
link.springer.com/article/10.1...
link.springer.com
Targeting the integrated stress response or Ataxin-2 alleviates neurodegeneration in PolyGR models of C9orf72 associated frontotemporal dementia and amyotrophic lateral sclerosis - Acta Neuropathologi...
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are fatal, early-onset neurodegenerative diseases. The most common genetic cause of FTD and ALS is a G4C2 hexanucleotide repeat ex...
