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Rob Stephenson

@nandemokaizen.bsky.social
120 followers 205 following 37 posts

Locum Senior Editor handling stem cells, developmental biology, mechanobiology, general physiology @nature.com 🇨🇦🇯🇵🏴󠁧󠁢󠁥󠁮󠁧󠁿🇨🇳 Views are my own

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Rob Stephenson @nandemokaizen.bsky.social · 31/05/2026
A big leap in mapping human embryo development and understanding our origins
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Reposted by Rob Stephenson
Nature @nature.com · 29/05/2026
Nature research paper: Human haematopoietic stem cells remember inflammatory stress go.nature.com/4dAUQqp
go.nature.com
Human haematopoietic stem cells remember inflammatory stress - Nature
Using xenograft inflammation–recovery models and single-cell multiomics, a haematopoietic stem cell population after inflammatory stress is identified.
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Stem Cell Network @stemcellnetwork.ca · 13/02/2026
📣 Calling stem cell researchers and GMP manufacturing specialists! The University of Alberta is hiring a #ResearchAssociate, Stem Cell Process Development & GMP Manufacturing to join the Shapiro Stem Cell Diabetes Lab, led by Dr. James Shapiro. Learn more and apply. ➡️ stemcellnetwork.ca/careers/
stemcellnetwork.ca
Careers in Stem Cell and Regenerative Medicine - Stem Cell Network
Explore job postings with the Stem Cell Network and SCN-funded labs across Canada Looking for career opportunities in the stem cell or regenerative medicine sector? Browse current openings for positio...
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Rob Stephenson @nandemokaizen.bsky.social · 29/01/2026
A wrap to a really great @keystonesymposia.bsky.social meeting in Kyoto, in what I half-suspect is a spaceship. It's fitting, because 20 years after the discovery that somatic cells could convert to pluripotent #stemcells, sci fi is definitely becoming science fact.
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James Briscoe @jamesbriscoe.bsky.social · 10/10/2025
The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...
crick.ac.uk
Early career group leaders
We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.
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Rita Strack @ritastrack.bsky.social · 24/09/2025
Nature Biomedical Engineering is hiring again! This time we're hoping to add an editor with machine learning expertise to the team (although we are open to those with other relevant expertise!) Deadline is Oct 20. Please RT! springernature.wd3.myworkdayjobs.com/SpringerNatu...
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Rob Stephenson @nandemokaizen.bsky.social · 07/10/2025
What a monumental contribution. Very sad loss.
share.google
Nobel Laureate Professor Sir John Gurdon Dies Aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
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Rob Stephenson @nandemokaizen.bsky.social · 28/09/2025
Dinner by the lake after a great Human Development meeting in Suzhou, China. Excellent science and insights at a lovely location. Massive thanks to the organizers, incl CSH Asia. Suzhou's neural tube shaped building a fitting bonus. #developmentalbiology #stemcells
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Rob Stephenson @nandemokaizen.bsky.social · 26/09/2025
The view from my window at 11:58 pm in Suzhou China. Could you please turn the dang building off so I can get some sleep?
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Rita Strack @ritastrack.bsky.social · 14/08/2025
There is still time to apply to become part of our team at Nature Biomedical Engineering! Please share! springernature.wd3.myworkdayjobs.com/SpringerNatu...
media.tenor.com
a blue sign that says we are hiring
ALT: a blue sign that says we are hiring
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Olena Zhulyn @ozhulyn.bsky.social · 25/07/2025
SickKids Research Institute has just launched a search for Program Head in Developmental, Stem Cell and Cancer Biology. Phenomenal colleagues, amazing science and great food all in the most multicultural city in the world. Join us: www.sickkids.ca/en/research/...
sickkids.ca
Developmental, Stem Cell & Cancer Biology | SickKids Research Institute
The Developmental, Stem Cell & Cancer Biology program has led significant discoveries in developmental genetics, genomics, stem cell and cancer biology.
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Nature @nature.com · 06/07/2025
The decades-old limit on how long human embryos can be grown in culture is under debate go.nature.com/3GnRpWg
go.nature.com
Human embryo research: how to move towards a 28-day limit
Nature - The decades-old limit on how long human embryos can be grown in culture is under debate. A new road map outlines how to extend the length of culture responsibly.
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Nature Cell Biology @natcellbio.nature.com · 06/06/2025
☕Attending the @isscr.org meeting next week and looking for a recap of interesting work in the field during the past year? Take a look at our collection of #StemCell and development papers published across @natureportfolio.nature.com during the past 12 months! www.nature.com/collections/...
nature.com
A year of stem cell and developmental biology
In recent years, the field of stem cell and developmental biology has seen remarkable breakthroughs that have deepened our understanding of how organisms ...
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Barack Obama @barackobama.bsky.social · 30/05/2025
At a time when people are understandably focused on the daily chaos in Washington, these articles describe the rapidly accelerating impact that AI is going to have on jobs, the economy, and how we live.
axios.com
Behind the Curtain: Top AI CEO foresees white-collar bloodbath
Hardly anyone is paying attention.
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Rob Stephenson @nandemokaizen.bsky.social · 31/05/2025
bbc.com
US government report cited non-existent sources, academics say
Authors of several studies cited in the report told news outlets they did not write them and the studies did not exist.
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Nature @nature.com · 28/05/2025
Trump signed an order mandating the overhaul of research-integrity policies so that the US government promotes “gold standard science”. But many researchers worry about political interference and are mobilizing opposition. go.nature.com/43EYiKo
go.nature.com
Trump’s call for ‘gold standard science’ has prompted an outcry: here’s why
Thousands have signed an open letter against the US president’s latest order, anxious about political interference in science and more.
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Nick Carnes @carnes.bsky.social · 21/05/2025
If we stop calling these “grants” and start calling them “contracts,” it’s clearer to people why this is such an abuse of power. This wasn’t a bunch of gifts. This was a bunch of binding contracts between researchers and the US govt for specific agreed upon projects.
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Rob Stephenson @nandemokaizen.bsky.social · 25/05/2025
Many CD and vinyl shops in Tokyo where you can make some great and rare finds
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Nature @nature.com · 22/05/2025
Nature research paper: Molecular basis of positional memory in limb regeneration go.nature.com/44OtQj3
go.nature.com
Molecular basis of positional memory in limb regeneration - Nature
A molecular analysis of axolotl limb regeneration has identified a positive genetic circuit that maintains posterior cell identity and can be used to reprogramme anterior cells into posterior cells.
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Rob Stephenson @nandemokaizen.bsky.social · 24/05/2025
Very cool! Please science, can you make nose plugs for breathing underwater next? (Of course, still early days for these lenses...)
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Rob Stephenson @nandemokaizen.bsky.social · 24/05/2025
Cell therapy approaches are potentially limited by low oxygen supply post transplantation. Multiomic analysis of #StemCell derived #pancreatic islet-like cells in hypoxic culture identifies EDN3 as a gene that preserves beta cell identity and function. #scRNAseq
nature.com
Improving cellular fitness of human stem cell-derived islets under hypoxia - Nature Communications
Hypoxia impairs the efficacy of stem cell-derived islet cell therapy, making it a potential barrier for treatment of type 1 diabetes. Wang et al. identify EDN3 as a key factor that preserves β cell id...
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Nature Communications @natcomms.nature.com · 21/05/2025
Come work with us! The Earth team at Nature Communications is looking to hire a new editor in the field of environmental carbon cycle, check the ad here and spread the word: springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor (environmental carbon cycle), Nature Communications
Job Title: Associate or Senior Editor (environmental carbon cycle), Nature Communications Location(s): Shanghai, Beijing, Nanjing, New York, Jersey City, Philadelphia, Washington DC, Milan, Madrid (Hy...
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Nature @nature.com · 18/05/2025
A baby boy with a devastating genetic disease is thriving after becoming the first known person to receive a bespoke, CRISPR therapy-for-one, designed to correct his specific disease-causing mutation go.nature.com/4ml3ZW6
go.nature.com
World’s first personalized CRISPR therapy given to baby with genetic disease
Nature - Treatment seems to have been effective, but it is not clear whether such bespoke therapies can be widely applied.
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Rob Stephenson @nandemokaizen.bsky.social · 18/05/2025
Technology is moving so fast nowadays, and in many cases testing ethical boundaries. A great article on strategies for enabling dialogue with the public.
sciencedirect.com
Identifying enabling strategies for effective public dialogue in human embryo research
Public dialogue is crucial for understanding societal views on human embryo research, and the complexity and sensitivity of this topic require special…
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Cell Stem Cell @cp-cellstemcell.bsky.social · 08/05/2025
Online Now! 3D reconstruction of a human Carnegie stage 9 embryo provides a snapshot of early body plan formation #stemcells
dlvr.it
3D reconstruction of a human Carnegie stage 9 embryo provides a snapshot of early body plan formation
Yu and his colleagues present a 3D spatial transcriptomic map of a CS9 human embryo, investigating several key developmental events during this critical stage of body patterning.
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Rob Stephenson @nandemokaizen.bsky.social · 18/05/2025
Grok (X's AI, commonly being used as a fact checker) was posting about "white genocide" in South Africa last week in response to EVERYTHING. Some suspect a clumsy patch installed. Seems the issue is resolved; perhaps dialled down to dispense more relevant propaganda? fortune.com/2025/05/15/e...
fortune.com
Elon Musk's AI says it was 'instructed by my creators at xAI' to accept the narrative of 'white genocide' in South Africa
"This directive caused me to inappropriately insert references to 'white genocide' into unrelated conversations," Grok told Fortune.
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Michael Baym @baym.lol · 14/05/2025
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
A screenshot of the termination notice showing "Outstanding Investigator Grants"A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted
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NEJM.org @nejm.org · 15/05/2025
A lipid nanoparticle–delivered base-editing therapy was custom designed for an infant with a ureacycle disorder. The affected infant was treated at approximately 7 and 8 months of age. Read the Brief Report: nej.md/42XF03F #ASGCT2025 #MedSky @asgct.bsky.social
nej.md
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM
Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...
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Nature Methods @natmethods.nature.com · 15/05/2025
Our colleagues at the Nature Research Cross-Journal Editorial team are also hiring for two new positions! 👇 Metabolism/cancer/aging/immunology/cell bio: springernature.wd3.myworkdayjobs.com/SpringerNatu... Neuroscience/genetics/genomics/mol bio: springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor, (Life Sciences) Research Cross-Journal Editorial Team, Nature Portfolio
Job Title: Associate or Senior Editor, (Life Sciences) Research Cross-Journal Editorial Team, Nature Portfolio  Location: New York, Jersey City, Shanghai, Beijing, or Nanjing Deadline: May 29th, 2025 ...
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Nature Biotechnology @natbiotech.nature.com · 12/05/2025
The Research Cross-Journal Editorial Team at @natureportfolio.nature.com is hiring! If you have a life science PhD and are curious about science beyond the bench, explore our open editor roles. JR102859: springernature.wd3.myworkdayjobs.com/SpringerNatu...
springernature.wd3.myworkdayjobs.com
Associate or Senior Editor, (Life Sciences) Research Cross-Journal Editorial Team, Nature Portfolio
Job Title: Associate or Senior Editor, (Life Sciences) Research Cross-Journal Editorial Team, Nature Portfolio  Location: New York, Jersey City, Shanghai, Beijing, or Nanjing Deadline: May 29th, 2025 ...
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Cell Stem Cell @cp-cellstemcell.bsky.social · 08/05/2025
Online Now! Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud #stemcells
dlvr.it
Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud
Shi, McCracken, and colleagues define methods to incorporate ureteric bud (UB)-derived collecting duct (CD) systems into hPSC-derived kidney organoids. The CDs integrate with nephrons through direct epithelial fusion to the distal nephron in a process emulating the developmental connection, which is regulated by key signaling and transcriptional mechanisms.
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Cell Reports @cp-cellreports.bsky.social · 04/05/2025
Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells
dlvr.it
Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells
Higaki et al. provided direct evidence that universal fibroblasts from the lung, the colon, and muscle differentiated into functional HSC niche cells, known as BM CAR cells. This is the first demonstration of the ability of universal fibroblasts to generate tissue-specific specialized fibroblasts.
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Nature Biotechnology @natbiotech.nature.com · 02/05/2025
The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson’s disease go.nature.com/44TCQ6u
go.nature.com
The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson’s disease - Nature Biotechnology
Patients with Parkinson’s disease treated with fetal tissue are assessed 3 years after surgery.
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Rob Stephenson @nandemokaizen.bsky.social · 09/05/2025
Wow, a new Pope. I know it is a first, and many people are saying it is crazy. It just doesn't seem right. But I think the church made a bold and progressive move by electing its first "Rob." This is a huge step for Robs everywhere, and I'm glad to see it finally happened.
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Arnau Sebé-Pedrós @arnausebe.bsky.social · 07/05/2025
Check out our latest work on the evolution of animal genome regulation out today in @nature.com. Nicely summarized below by @ianakim.bsky.social. www.nature.com/articles/s41... This is a major output from our ERC-StG project Evocellmap @erc.europa.eu at @crg.eu
nature.com
Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature
The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...
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Rob Stephenson @nandemokaizen.bsky.social · 04/05/2025
Congratulations to Mark Carney for the Canadian election. Great qualifications, and seems to have a plan and a spine. A big job ahead. #GameOfThrones #CanadaVotes #CanadianElection
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Rob Stephenson @nandemokaizen.bsky.social · 04/05/2025
More reports of threatening letters to research journals from the US Justice Department, including to The New England Journal of Medicine.
npr.org
Medical journals hit with threatening letters from Justice Department
The interim U.S. attorney for the District of Columbia has sent letters to several leading medical journals asking for information about their editorial practices.
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KatajistoLab @katajistolab.bsky.social · 28/04/2025
Happy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells www.nature.com/articles/s41... @metastem.bsky.social @helsinki.fi @ki.se @helsinki-biotech.bsky.social out now in @natcomms.nature.com A thread 🧵 1/9
nature.com
Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division - Nature Communications
Peroxisomes are essential but their role in cell fate regulation remains understudied. Here, the authors reveal that young and old peroxisomes are not equally distributed in asymmetrically dividing st...
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Rob Stephenson @nandemokaizen.bsky.social · 28/04/2025
It's really nice to wake up in Tokyo and find your team won the Premier League title :) #YNWA #LFC
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Rob Stephenson @nandemokaizen.bsky.social · 27/04/2025
Mitochondria membrane potential contributes to the selective advantage of clonal #hematpoiesis related Dnmt3a mutations in #StemCells #Mitochondria
nature.com
Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis - Nature Communications
Clonal hematopoiesis is driven by the selective advantage of mutant hematopoietic stem cells. Here, authors discover that elevated mitochondrial activity is a targetable mechanism by which mutant hema...
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Rob Stephenson @nandemokaizen.bsky.social · 27/04/2025
You can still opt out in the US... for now. People often criticize the extensive surveillance in China - this is how it started.
huffpost.com
Why You Can (And Should) Opt Out Of TSA Facial Recognition Right Now
Do you really want to be submitting a face scan to the current U.S. government?
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Rob Stephenson @nandemokaizen.bsky.social · 27/04/2025
Voted. Dropped my ballot off at the Canadian Embassy in Tokyo. Got a really lovely view of the city as a reward 😊 #CanadaVotes #CanadianElection
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Development @dev-journal.bsky.social · 22/04/2025
Stem cell-based models of early human development Read this Development at a Glance Article by Lizhong Liu @liliulab.bsky.social and Jun Wu @jun-wu-lab.bsky.social: journals.biologists.com/dev/article/...
Poster titled Stem cell-based models of early human development
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Jennifer Trowbridge @trowbridgelab.bsky.social · 16/04/2025
New paper from my lab! Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis: rdcu.be/eh1Nb Complementary to new work from Steven Chan & @georgevassiliou.bsky.social as described by @goodell-lab.bsky.social: www.nature.com/articles/d41...
nature.com
Age-related blood condition counteracted with a common diabetes drug
Metformin could reduce people’s risk of certain age-associated blood cancers, but more work is needed to identify who is likely to benefit.
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Nature @nature.com · 18/04/2025
Nature research paper: Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs go.nature.com/3Rm4rVZ
go.nature.com
Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs - Nature
Dnmt3a mutations in mouse haematopoietic stem and progenitor cells equivalent to R882 mutations in human cause increased mitochondrial respiration, suggesting that this is a mechanism of clonal haematopoiesis and a potential therapeutic target.
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Rob Stephenson @nandemokaizen.bsky.social · 24/04/2025
Researchers are getting ready to leave the US
nature.com
Exclusive: a Nature analysis signals the beginnings of a US science brain drain
A trawl of job views and application data suggests jobseekers are looking abroad as the Trump administration’s cuts to science take hold.
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Rob Stephenson @nandemokaizen.bsky.social · 20/04/2025
Fellow Canucks abroad! A bit tight, but still time to vote. Deadline to apply online for your voting kit is Apr 22. Mail in ballot must be received by Apr 28, 6 pm, Eastern time. All the more important to vote after ridiculous threats to our home. #CanadaVotes #CanadianElection
elections.ca
Voting by mail – Elections Canada
Apply to vote by mail, Eligible electors can apply to vote by special ballot. With a special ballot, you can vote by mail from anywhere in the world, 2025.
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Nature @nature.com · 16/04/2025
Nature research paper: Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease go.nature.com/4ikgYEu
go.nature.com
Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson’s disease - Nature
After transplantation into the brain of patients with Parkinson’s disease, allogeneic dopaminergic progenitors derived from induced pluripotent stem cells survived, produced dopamine and did not form tumours, therefore suggesting safety and potential clinical benefits for Parkinson’s disease.
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Nature @nature.com · 18/04/2025
Nature research paper: Generation of human adult hepatocyte organoids with metabolic functions go.nature.com/43WXrX7
go.nature.com
Generation of human adult hepatocyte organoids with metabolic functions - Nature
The combined activation of Wnt and STAT3 signalling enables long-term self-renewal of human hepatocyte organoids, maintaining hepatic identity, supporting gene editing and offering therapeutic potential for liver disease through enhanced functionality, structure and metabolic competency.
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Rob Stephenson @nandemokaizen.bsky.social · 16/04/2025
A landmark in medicine!
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