Normal bladder fibroblasts rapidly engage in bidirectional crosstalk with bladder cancer cells, acquiring cancer-associated fibroblast-like activation features while promoting wound closure, epitheli...

In vitro studies of antimicrobial resistance (AMR) using laboratory growth media produce important, fundamental information. However, their inability to more closely replicate the in vivo environment ...

Antimicrobial resistance (AMR) increasingly poses a significant global health challenge. New antimicrobials are desperately needed, driving the need to explore novel sources of natural products. Snake...

Utebzi is the first oral carbapenem antibiotic approved in the US.

British Journal of Cancer - An advanced in vitro bladder cancer model integrating bladder cancer spheroids into a healthy human urothelium for preclinical therapeutic testing

British Journal of Cancer - An advanced in vitro bladder cancer model integrating bladder cancer spheroids into a healthy human urothelium for preclinical therapeutic testing

Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin…

Researchers at the Johns Hopkins Kimmel Cancer Center have discovered how certain pathogenic bacteria in gut and breast tissue can promote breast cancer development and progression by hijacking a key…

npj Antimicrobials and Resistance - Effect of host microenvironment and bacterial lifestyles on antimicrobial sensitivity and implications for susceptibility testing