iiinova — where your digital self keeps evolving

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Critical Care Reviews @criticalcarereviews.com · 03/04/2025

Venous excess ultrasound: A mini-review and practical guide for its application in critically ill patients CCR Journal Watch - tracking the critical care literature daily criticalcarereviews.com/latest-evid…

0104

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

EASL @easlnews.bsky.social · 05/03/2025

🧪We are now calling for late-breaker abstracts for #EASLCongress 2025. Take this unique opportunity to showcase your research, connect with the global liver health community, and shape the future of hepatology. Submission deadline: 17 March 2025 www.easlcongress.eu/2025-abstrac...

021

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 24/03/2025

Great review for fluids+cirrhosis! 🌊 “The complex circulatory changes associated with cirrhosis and the hyperdynamic state, characterised by increased splanchnic blood volume and relative central hypovolemia, complicate fluid administration and monitoring of fluid status.”

010

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Critical Care Reviews @criticalcarereviews.com · 24/03/2025

Today's Paper of the Day is: Fluid resuscitation in patients with cirrhosis and sepsis: A multidisciplinary perspective criticalcarereviews.com/latest-evid… Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

034

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Jack Iwashyna @iwashyna.bsky.social · 13/03/2025

Science is good for America

2218

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Jack Iwashyna @iwashyna.bsky.social · 20/02/2025

Over on LinkedIn, the head of the Executive Secretariat of the NIH -- a central part of NIH leadership 🧪🩺-- resigned with a lettter worth reading www.linkedin.com/posts/nathan...

February 18, 2024
TO:
Dr. Matthew Memoli, Acting Director, NIH
CC:
John Burklow, Chief of Staff, NIH
Julie Berko, Director, OHR, NIH
FROM:
Nathaniel James Brought, Director, ES, NIH
SUBJECT: Resignation
Dear Dr. Memoli,
On July 3, 2001, I stepped off a bus on Marine Corps Recruit Training Depot Perris Island. Scared out of my mind, I stood on a pair of freshly painted yellow footprints, raised my right hand, and recited the oath of enlistment:
I, Nathaniel James Brought, do solemnly swear that I will support and defend the Constitution of the United States against all enemies, foreign and domestic; that I will bear true faith and allegiance to the same; and that I will obey the orders of the President of the United States and the orders of the officers appointed over me, according to regulations and the Uniform Code of Military Justice. So help me God.
For the last 23 years, 7 months, and 15 days, I like to believe I have faithfully carried out the duties of each office to which I've been appointed in my military and civilian service to this nation. That Service has taken me from the Marine Corps to 3 different federal departments, spanned 3 continents, included service in one war zone, and has included:
• For the Marine Corps and the National Security Agency, I worked on intelligence operations at the highest classification levels using bleeding edge intelligence tools to ensure America's special operators put boots-to-asses on America's enemies overseas (including commendations crediting my work for the kill or capture of dozens of terrorists), ensuring America's policy makers were able to track the movement of dangerous dual

nuclear technology across international borders, and monitored the flow of terrorist financing across the international banking system.
• Utilized information from all-source intelligence to ensure the continued security of America's homeland from international and domestic threats.
• Worked with some of the finest lawyers in the world to ensure America's security operations were effective, while upholding the rights of all those who interacted with them.
• Ensuring that America's rural communities had access to programs like rural development loans, farm aid, and that America's children wouldn't be hungry as they sat in their classrooms and tried to learn.
• Most recently, and frankly most dear to my heart, working with each of you here at the National Institutes of Health to advance the future of science and medicine. Not for Americans. Not for any one group of people. But for ALL of humanity.
I am unbelievably proud to be able to say that there are Americans who are alive, and terrorists who are not, because of the work I've done to serve this nation. I am proud to say that my service to this country has allowed me to ensure that my children have never faced the struggles of poverty that I grew up with. That service didn't begin because of some great altruistic impulse or drive. I didn't grow up saying "I want to do the great work that needs to be done to weave the fabric of America and ensure her people are not only safe, but healthy." Frankly, that service began because I was poor, and I was inspired. I grew up as a free lunch kid who lived in project housing. It was my fellow Americans who made sure I wasn't hungry in class and that I had enough food to excel academically the way I did. It was Americans who had more than we did that made sure I had good schools to attend where I could learn things that expanded my mind.
As I approached the end of high school, I dreamed of going to college and figuring out how to make a living that would allow me to do more tha…

461251641

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Elliot Tapper @ebtapper.bsky.social · 17/12/2023

journals.lww.com/hepcomm/page... Malpractice claims in hepatology How often Why And what’s the outcome

021

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/02/2025

Congrats! Having your first author pub in print is really special! 🎉

110

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/02/2025

Exciting research on personalized albumin dosing in decompensated cirrhosis! Can’t wait to see the results! 🤓

020

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Critical Care Reviews @criticalcarereviews.com · 23/12/2024

The acute phase management of traumatic spinal cord injury CCR Journal Watch criticalcarereviews.com/latest-evid… Get the latest critical care literature every weekend via the CCR Newsletter - subscribe at criticalcarereviews.com/newsletters…

061

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Dr. Glaucomflecken @glaucomflecken.bsky.social · 11/12/2024

youtu.be/JfyECL2UtMw?... I’ve been getting a lot of new comments on old videos for some strange reason

youtu.be

30 Days of US Healthcare: United Healthcare Denies Everything

YouTube video by Dr. Glaucomflecken

21702141

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 19/12/2024

This is the magic of sisterhood because she would do the exact same with your gift

030

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 19/12/2024

CRRT ineffective for removing lactate! Treating the underlying pathology will correct the lactatemia ⚡️

130

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 19/12/2024

Exciting development for drug discovery in MASH-cirrhosis! Always love a translational model 🐀

020

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 19/12/2024

Yea- it has OG #pharmICU vibes and I love it. Go find @ajwpharm.bsky.social He has starter packs you can follow! Great place to get started!

130

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Alex Chang, MD @alexchangmd.bsky.social · 18/12/2024

Updated ADA standards of Care 2025 : for T2D + CKD - recommends use of SGLT2 OR GLP1-RA with proven CKD benefit diabetesjournals.org/care/article...

0167

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 17/12/2024

I wonder if it’s just a logistic problem? Easier to warm the blood return line than keep the whole tubing set of the dialysate fluid warm.. we would have major issues with the warmers in the hospital too (with CRRT), breaking, over heating..

010

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 17/12/2024

Any concerns for solution stability at the higher temperature?

110

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 17/12/2024

This story is 💯 % worth your time and nothing short of 🤯 🤯

011

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Paul Eric @pauleric70.bsky.social · 16/12/2024

Bryce Canyon National Park at sunrise 🇺🇲 Stunning capture ✨🧡✨🧡✨🧡✨

19012433841

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

ASNKidney @asnkidney.bsky.social · 16/12/2024

🚨 Now Hiring: ASN is seeking an Editor-in-Chief for Kidney360 🌟 Lead innovation in nephrology, drive research, and shape the future of kidney care. Apply by Jan 31, 2025. Apply today. 👉 bit.ly/Kidney360EIC #Kidney360 #Nephrology #JobAlert

064

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/12/2024

It’s the derivation of this equation (from Josh’s link to the Matzke nonogram paper) which plots vancomycin Cl (ke-1) to CrCL.. Ke=0.00083(CrCL) + 0.0044 Also need to advocate this type of work is a clinical pharmacists bread and butter, and one of the many reasons we need Pharmds at the bedside.

0145

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/12/2024

0145

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/12/2024

All the time! One of my favorite tricks to assess the GFR! 🙌🏻

150

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/12/2024

Some more depressing US quality of lifespan data to start your Monday.. ☹️

022

Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP @mtbastin.bsky.social · 16/12/2024

Love to see this work of sex differences in outcome response being done. But it needs to happen as part of the primary hypothesis and not in retrospect.. ✨ #womenshealth

021

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · 14/12/2024

Can we use Dual β-lactam? One example is Cefazolin and Ertapenem, a synergistic combination used in the treatment of persistent MSSA bacteremia Mechanism 👇 Can you think of other examples for dual β-lactam? #idsky #medsky #EMIMCC #microsky

6143

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

💉Josh Rubin, MD @drsandman11.medsky.social · 13/12/2024

Just a bunch of people living their lives, using their natural immunity, not a vax in sight

Polio ward with rows of patients in iron lungs

7339125

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Mark Hamill @markhamillofficial.bsky.social · 12/12/2024

Posted this at the old place, but thought folks on @bsky.app might like to know I finally met my "mother".

29081464689115

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Edgar V. Lerma 🇵🇭 @edgarvlermamd.medsky.network · 12/12/2024

Peritonitis Guideline Recommendations 2022 from @ispd1.bsky.social: Management algorithms #Nephpearls #NephSky 📌 Initial management for those presenting w/ clinical diagnosis of peritonitis 📌 Coagulase negative Staphylococcus 📌 Culture negative peritonitis 👉 pubmed.ncbi.nlm.nih.gov/35264029/

084

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

@IM_Crit_ @imcrit.bsky.social · 11/12/2024

For #POCUS #VExUS aspiring users: 1. VExUS can assess only the dark side of the moon: the venous side. A detailed hemodynamic assessment should look also at the 💙 itself (RV/LV function, pericardial effusion etc) & the lungs (B-lines? effusions?) 2. VexUS does not assess for volume responsiveness

2185

Reposted by Melissa Thompson Bastin, PharmD, PhD, BCCCP, FCCM, FCCP

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 12/12/2024

The Global Kidney Patient Trial Network and the CAPTIVATE Platform trials are now mainstream in nephrology! jamanetwork.com/journals/jam...

Figure 1. The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect (CAPTIVATE) Study Design

295