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Michael Schellenberger

@mschellenberger.bsky.social
153 followers 218 following 6 posts

PhD student in the Moser lab @kavlintnu.bsky.social

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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 06/08/2026
Out now in @science.org : How does the brain rapidly scan space to guide navigation? We found that the brain’s internal map is continuously retuned from moment to moment, focusing neural activity on what matters most. 🧵1/8 👉 www.science.org/doi/10.1126/...
science.org
Adaptive modulation of theta sweeps in the brain’s navigation circuit
Efficient navigation requires prioritizing information from behaviorally relevant locations. In rats, such selective sampling may arise from theta-paced sweeps in grid and place cell populations, whic...
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Reposted by Michael Schellenberger
The Transmitter @thetransmitter.bsky.social · 06/08/2026
For 30 years, neuroscientists have argued about whether theta sweeps are just passive sensing, or something closer to planning. So which is it? #neuroskyence By @natmesanash.bsky.social www.thetransmitter.org/memory/new-f...
thetransmitter.org
New findings begin to resolve theta sweep debate
Theta sweeps have been mired in controversy for decades, but the emerging consensus view suggests that they function in attention and goal direction.
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Reposted by Michael Schellenberger
Abraham Zelalem Vollan @azvollan.bsky.social · 06/08/2026
Now in Science: How does the brain’s navigation system allocate its limited representational resources during behavior? We found that grid cells sweep toward locations of interest, providing a potential mechanism for allocating spatial attention in the cognitive map.🧵 science.org/doi/10.1126/...
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Reposted by Michael Schellenberger
Mohammed Khallaf @khallaf.bsky.social · 15/07/2026
Our new paper is out in @nature.com! We uncovered how a naked mole-rat queen 👑 controls an entire colony: a natural contraceptive scent that suppresses reproduction in other females! A remarkable mammalian parallel to bees and ants! 🐝🐜 @garyrlewin.bsky.social youtu.be/enfv3zJrWKM?...
youtu.be
Naked mole-rats are ruled by a queen: this chemical puts her in power
YouTube video by nature video
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Reposted by Michael Schellenberger
Oscar Chadney @oscar-chadney.bsky.social · 09/07/2026
I’m excited to share our latest preprint, and the main work from my PhD, on the role of the direct entorhinal input in hippocampus CA1 spatial coding. 1/9
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Reposted by Michael Schellenberger
Jo Carpenter @jocarpenter.bsky.social · 07/07/2026
The Moser Group is presenting our work on Wednesday afternoon at #FENS2026! •Mechanism for L-R sweeps •Attention modulation of sweeps •Grid/place remapping rules & dynamics •”Mega torus” as a hi-capacity memory space •Moving the grid bump •Development of tori & rings •RSC/HC pops. in a spatial task
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Reposted by Michael Schellenberger
Emre Yaksi @emreyaksi.bsky.social · 02/07/2026
I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.
science.org
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...
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Michael Schellenberger @mschellenberger.bsky.social · 11/03/2026
Such a fantastic study! Congrats @matteoguardamagna.bsky.social and co-authors!
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Reposted by Michael Schellenberger
Matteo Guardamagna @matteoguardamagna.bsky.social · 11/03/2026
7/7 Take-home message: core computational architectures for spatial cognition are intrinsically self-organized. Navigational experience aligns and anchors them to the external world.
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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 11/03/2026
Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4 👇 www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Michael Schellenberger
Matteo Guardamagna @matteoguardamagna.bsky.social · 11/03/2026
1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵
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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 19/02/2026
A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...
pnas.org
Place cells in CA1 lack topographical organization of firing locations | PNAS
Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...
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Reposted by Michael Schellenberger
Lucie Descamps @ldescamps.bsky.social · 10/02/2026
My first first-author paper is on bioRxiv! Here we ask whether the same subset of neurons in ACC always display object correlates during extensive familiarisation to 2 objects. A short 🧵1/10
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Reposted by Michael Schellenberger
Abraham Zelalem Vollan @azvollan.bsky.social · 28/01/2026
By adjusting the direction, width and frequency sweeps, the sweep system may provide a mechanism for allocating spatial attention in allocentric hippocampal maps. Check out the preprint for more findings and videos! www.biorxiv.org/content/10.6...
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Reposted by Michael Schellenberger
Abraham Zelalem Vollan @azvollan.bsky.social · 28/01/2026
We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:
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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 28/01/2026
Whether the system can be flexibly redirected to prioritize specific locations has been unclear. Using large-scale #Neuropixels recordings in freely behaving rats, we find that both sweeps – and the internal direction signals driving them – are dynamically modulated moment by moment. (4/6)
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Michael Schellenberger @mschellenberger.bsky.social · 28/01/2026
Theta sweeps can track moving bait and go backwards!
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Reposted by Michael Schellenberger
Horst Obenhaus @octoscience.bsky.social · 23/12/2025
Do you love quantifying animal behavior as much as we do? We have just the tool for you! Presenting #OCTRON - a pipeline that helps you create rich annotation data and enables training of custom segmentation models. Have a look, particularly if you work with non-model / invertebrate organisms!
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Reposted by Michael Schellenberger
Matteo Guardamagna @matteoguardamagna.bsky.social · 18/11/2025
Still at SfN on the last day? During the morning session on the 19th, 8:00AM - 12:00PM, come check out our posters from the Moser, Zong, and Gonzalo Cogno groups in row QQ ('Grid cells and spatially modulated cells'). Ephys, imaging, remapping, development, sweeps and more! 🧠 Detailed thread below 👇
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Michael Schellenberger @mschellenberger.bsky.social · 18/11/2025
Check out the work @azvollan.bsky.social and I present tomorrow morning #SfN25
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Reposted by Michael Schellenberger
Jo Carpenter @jocarpenter.bsky.social · 15/11/2025
SFN 2025 let’s gooo!! Moser group posters are held Wednesday morning (QQ), so if you’re leaving early feel free to come find us to chat :)
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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 25/09/2025
1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵 Preprint link 👇 www.biorxiv.org/content/10.1...
biorxiv.org
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
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Reposted by Michael Schellenberger
Rajat Saxena @rajatsxn.bsky.social · 30/06/2025
Our work with Maxim Bazhenov's group showing interleaved replay of new and old memories within individual Up states using a combination of biophysical modeling and electrophysiology experiments.
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Reposted by Michael Schellenberger
Ben Kanter @beneuroscience.bsky.social · 26/06/2025
Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇
science.org
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 26/06/2025
Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...
science.org
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
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Reposted by Michael Schellenberger
Abraham Zelalem Vollan @azvollan.bsky.social · 04/02/2025
Excited to share that our paper is now published in Nature! In this study, we uncovered a grid-cell-based circuit in medial entorhinal cortex that probes the surrounding environment with theta-paced, sweeping spatial representations 🧵 www.nature.com/articles/s41...
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Michael Schellenberger @mschellenberger.bsky.social · 03/02/2025
Congrats @azvollan.bsky.social & @rjgardner.bsky.social & @edvardmoser.bsky.social & @m-bmoser.bsky.social 🎉🎉🎉 Fantastic paper!
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Reposted by Michael Schellenberger
Edvard I Moser @edvardmoser.bsky.social · 03/02/2025
Grid cells have a geometry in time. Thanks to @azvollan.bsky.social l & @rjgardner.bsky.social for this heroic discovery. @ercresearch.bsky.social #KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com @kavlifoundation.bsky.social www.nature.com/articles/s41...
nature.com
Left–right-alternating theta sweeps in entorhinal–hippocampal maps of space - Nature
A study in rats proposes a mechanism for how the brain maps the surrounding environment, including places it has never seen, by alternating left and right forward sweeps in successive theta cycles.
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Reposted by Michael Schellenberger
Weijian Zong @weijianzong.bsky.social · 15/01/2025
Attention! Zong lab is recruiting!! Two Ph.D and postdoc positions in neuroscience 🧠 are available!! Apply if you are strongly interested in applying cutting-edge @TheMini2P 🔬 for frontier systems neuroscience studies!!!! www.jobbnorge.no/en/available...
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Reposted by Michael Schellenberger
Jo Carpenter @jocarpenter.bsky.social · 28/11/2024
Thankful for a loving family, all of my super funny friends, a happy and collaborative lab environment, and my rat Rafael for giving me some beautiful data tonight 🤩🥰🍗
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