The study unveils that potent combination therapies remodel TAMs to antitumor proinflammatory M1-like macrophages crucial for their therapeutic efficacy. I

This study reveals that anti-NS1 IgA antibodies in plasma, induced by prior Zika virus infection, activate neutrophils, underlying severe dengue disease upon a subsequent DENV2 infection, uncovering a...

Shimon Sakaguchi recounts the work that lead to the identification of regulatory T cells.

Tissue macrophages reside in anatomically distinct subtissular niches that shape their identity and function. In white adipose tissue (WAT), we identified three macrophage populations with distinct lo...

Neutralization tests for the virus of poliomyelitis on blood serum of urban mothers and their newborn infants showed that immunity was present in ten out o

COPA syndrome causes lung hemorrhaging starting in childhood. But one in three people with the disease mutation are spared. UCSF scientists have discovered how a separate gene variant protects those r...

Mutations in the KRT14 gene cause epidermolysis bullosa simplex (EBS), featuring abnormal basement membrane zone (BMZ) function. We identified deleterious

Michael Lauer, deputy director of the National Institutes of Health’s extramural research, will leave the agency at the end of the week.

The NIH said Friday night that it would slash support for indirect costs on all existing and future grants to 15%

The freeze’s effect on research is still unclear, but scientists fear ‘incalculable’ damage.

Study on hydroxychloroquine by Didier Raoult and colleagues gets pulled on ethical and scientific grounds