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Reboldi Lab

@reboldilab.bsky.social
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Mucosal Immunology Lab @umasschan.bsky.social www.umassmed.edu/reboldilab

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UMass Chan Medical School @umasschan.bsky.social · 20/07/2026
Read about the groundbreaking neuroscience research that UMass Chan faculty are doing: direc.to/o_Hn These interdisciplinary teams have received funding from the Dan and Diane Riccio Fund for Neuroscience. #neuroscience @reboldilab.bsky.social @sthyme.bsky.social @briankelch.bsky.social
Stephanie Puig, PhD, and Andrea Reboldi, PhDSummer Thyme, PhD, and Brian Kelch, PhD
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Michela Locci @michelalocci.bsky.social · 16/12/2025
I am excited to share that our work, in which we have dissected the signals driven by the nucleoside-modified mRNA and LNP components of mRNA vaccines that regulate germinal center (GC) responses, is now published in Cell! www.cell.com/cell/fulltex...
cell.com
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses
This study dissects the individual contributions of the different components of mRNA vaccines to immune responses. Nucleoside-modified mRNA promotes the production of type I interferons that act on de...
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Reposted by Reboldi Lab
Frascoli Lab @frascolilab.bsky.social · 18/09/2025
Excited to be part of this Women in STEM Viepoint 🌟 Huge thanks to @jem.org for the invite - what an inspiring lineup!
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Frederick "Erick" Matsen @matsen.bsky.social · 19/08/2025
Why does selection feel so weak relative to mutation in affinity maturation? A new blog post giving three perspectives, including our new transformer-based model of natural selection on antibodies: matsen.group/general/202...
matsen.group
The term 'affinity maturation' understates the influence of somatic hypermutation
Three recent papers quantify how nucleotide-level mutation processes drive antibody evolution.
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Mauro Gaya @maurogaya.bsky.social · 29/05/2025
Dr. Andrea Reboldi from UMass Chan Medical School 🇺🇸 will be presenting his work on "Metabolic regulation of intestinal humoral response". Check his recent study on how receptor signaling controls gut humoral response: pubmed.ncbi.nlm.nih.gov/37714151/ @reboldilab.bsky.social #EMBOBarrierTissues
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Mauro Gaya @maurogaya.bsky.social · 30/04/2025
🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues. 📍 Where: Basel, Switzerland 📅 When: 26th–29th August 2025 📝 Registration deadline: 30th May 2025 Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social #EMBOBarrierTissues
meetings.embo.org
Adaptive immunity in barrier tissues
Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…
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Journal of Experimental Medicine @jem.org · 19/02/2025
Kellog, @reboldilab.bsky.social, Vanni et al. reveal that #microbiome-driven tuft cells’ hyperplasia in the colon helps defend against Clostridioides difficile infection. buff.ly/3CRIPNy 📘 In Host–Microbe Interactions 2025 👉 buff.ly/40XMv8r
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Mucosal Immunology @mucosalimmunol.bsky.social · 27/01/2025
Follow our new podcast for more Mucosal Immunology - #MucosalMondays, coming to you the last Monday of every month.
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Carolyn King @immunologyking.bsky.social · 19/12/2024
Registration is live!! May 30th deadline for #EMBOTissueImmunity in Basel🇨🇭 (home to Eurocup 2025, Eurovision 2025, Art Basel, world renowned architecture and muuuuuch more!) Be our guest for groundbreaking #immunology discussion, swimming & fun along the Rhine. meetings.embo.org/event/25-bar...
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UMass Chan Medical School @umasschan.bsky.social · 12/12/2024
Toronto-based ImmVue Therapeutics Inc. has licensed cancer-fighting technology from UMass Chan Medical School: direc.to/m4zC This partnership was facilitated by BRIDGE Innovation and Business Development at UMass Chan.
direc.to
UMass Chan licenses potential small molecule immunotherapeutic for cancer treatment to ImmVue Therapeutics Inc.
Toronto-based ImmVue Therapeutics Inc. has exclusively licensed allosteric small molecule compounds identified in the laboratory of Joonsoo Kang.
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Reposted by Reboldi Lab
Carolyn King @immunologyking.bsky.social · 10/12/2024
Speaker line up for #EMBOTissueImmunity to take place in Basel 🇨🇭 26-29 August 2025. Come join @maurogaya.bsky.social and I for some fantastic #immunology along the Rhine! Please share this invitation - we hope you will join us. Registrations will be open soon.
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Waggoner Lab @labwaggoner.bsky.social · 26/11/2024
Microbiome-derived succinate-driven tuft cell hyperplasia in the colon helps defend against Clostridioides difficile infection, providing a pathway through which host/microbe interactions protect against pathogens doi.org/10.1084/jem.... @reboldilab.bsky.social @jexpmed.bsky.social
doi.org
Succinate-producing microbiota drives tuft cell hyperplasia to protect against Clostridioides difficile
The microbial metabolite succinate promotes tuft cell hyperplasia, which enhances the gut’s ability to protect against intestinal infections. This study re
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