Reposted by Peter RepettiDoudna Lab @doudna-lab.bsky.social · 16/07/2026Our AI-guided design of RNA-guided nucleases is now out in @science.org 💻🧬 We used structure and evolutionary data to generate minimal, active and divergent gene editors! www.science.org/doi/10.1126/... Congrats to @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social & team!science.orgStructure and evolution-guided design of minimal RNA-guided nucleasesThe design of RNA-guided nucleases with properties not limited by evolution can expand programmable genome-editing capabilities. However, generating diverse multidomain proteins with robust enzymatic ... 212841
Peter Repetti @monstera999.bsky.social · 08/07/2026I had a magical ~2 weeks with a family of barred owls in my Durham, NC backyard. I'd like to introduce you to Henrietta, X-the-Owl, Frazzle and Dazzle. Enter w/ sound, and a 2-min slideshow plays introducing you to the family, then there are lots more photos + sound stuff. Hoot!the-barred-hours.pages.devThe Barred HoursA Barred Owl family in photographs, video, and a night score built from their own calls. 061
Peter Repetti @monstera999.bsky.social · 07/05/2026Our neighborhood red-shouldered hawk Leviticus caught mid-launch from a set constructed of winter tulip poplar flower skeletons — ballet meets biomechanics. Talons en pointe, wings at full extension. Choreographed liftoff. #InMotion #BirdOfTheDay #RSHA 2284
Peter Repetti @monstera999.bsky.social · 04/05/2026Heckle and Jeckle, Barred Owl siblings raised in our Durham NC yard during the 2024 summer. Branchlings still figuring out the wing thing; one balanced, one workshopping a repositioning maneuver. #Pairs #BirdOfTheDay #BAOW 0211
Peter Repetti @monstera999.bsky.social · 03/05/2026“Here, I got these bugs for you.” Common Grackle with a beak-full of crunchy snacks for #BirdOfTheDay #mouthful. 1335
Peter Repetti @monstera999.bsky.social · 24/04/2026Carolina Wren, full-throated teakettle-teakettle in the rain. 20 grams of bird, wildly disproportionate volume. SO LOUD. Durham, NC. #BirdOfTheDay #TheSongFactor #CARW #birding 2363
Peter Repetti @monstera999.bsky.social · 23/04/2026Imagine, you’re finally the star in a movie about your life, or at least how you take a bath, and this diva just walks onto the stage, unannounced, and steals the show with THAT LOOK. #OvenBirdUpstage #birding 030
Peter Repetti @monstera999.bsky.social · 22/04/2026The backyard bath's informal "two splashers max" policy, strictly enforced by a pair of American Robins. Vigorous bathing realigns feather barbs and flushes ectoparasites; essential upkeep when you're defending turf and feeding babies. Durham, NC. #SplashingAround #AMRO @robcrank68.bsky.social 1152
Peter Repetti @monstera999.bsky.social · 21/04/2026Yellow-crowned Night-Heron, breeding plumes raised, posing beside Iris pseudacorus — beautiful, and unfortunately invasive in NA wetlands. Alas, the heron didn't make the landscaping decisions. Sandy Creek Park, Durham, NC. #YCNH #PetalsAndPerches #BirdOfTheDay 1352
Peter Repetti @monstera999.bsky.social · 14/04/2026Rorschach test, avian edition. Striking Great Egret! The water handled the symmetry. #BirdOfTheDay #Reflections #GREG #birding 0211
Peter Repetti @monstera999.bsky.social · 12/04/2026"Can I help you?" TFW you make eye contact with a Great Egret and realize you're the one being watched. Its neck is a spring-loaded spear, with 20 cervical vertebrae coiled and ready to strike at fish faster than you can blink. #GREG #LongNecks #BirdOfTheDay 1394
Peter Repetti @monstera999.bsky.social · 07/04/2026April's golden ticket just arrived. Prothonotary Warblers migrate from Central and South American mangroves to breed in southeastern bottomland swamps; a very long journey for a bird that weighs less than a AAA battery. Durham, NC. #BirdOfTheDay #PROW #warblers 1322
Peter Repetti @monstera999.bsky.social · 05/04/2026Nobody photographs the back of a peacock display, which is exactly why you should. The brown wing coverts, the gray structural rectrices doing all the work, the fluffy white undertail. Every diva has a stage crew. #BirdOfTheDay #Feathers #INPE #IndianPeafowl 1343
Peter Repetti @monstera999.bsky.social · 04/04/2026Jewelweed and hummingbirds: a 20-million-year-old handshake. The flower's spur is sized exactly for that bill, and the pollen lands exactly on that forehead. Ruby-throated Hummingbird, Durham, NC. #BirdOfTheDay #SmallBirdsInFlight #RTHU #NativePlants 26712
Peter Repetti @monstera999.bsky.social · 03/04/2026A Golden-crowned Kinglet picking through snow and oak leaves back in January. Weighs as much as two nickels but spends the whole winter here, burning through its body weight in insects daily just to stay warm. Durham, NC. #BirdOfTheDay #weather #GCKI #birding 1242
Peter Repetti @monstera999.bsky.social · 02/04/2026Great Blue Heron overhead! Wingspan: 6 ft (1.8m) — wider than most humans are tall. Standing height: 4 ft (1.2m). Weight: about 5.5 lbs (2.5 kg). They're essentially a fishing spear disguised as a kite. Durham, NC. #BirdOfTheDay #LargeBirdsInFlight #GBHE 2454
Peter Repetti @monstera999.bsky.social · 01/04/2026"I'll try the lobster." Yellow-crowned Night-Heron with a specialized crustacean-crushing bill to back it up. Sandy Creek Park, Durham, NC. #BirdofTheDay #snacks #YCNH #birding 7668
Peter Repetti @monstera999.bsky.social · 29/03/2026Not a goose. Not originally from Egypt. Not native to Florida. But when you have five kids, taxonomy is the last thing on your mind. The Egyptian Goose is a shelduck that escaped captivity and has built a life where it found itself. #BirdOfTheDay #AdultsWithChicks #birding 1243
Peter Repetti @monstera999.bsky.social · 28/03/2026The Blue Grosbeak: half color, half engineering. "Gros bec" in French is literally "big beak." He is a seed-crushing specialist wrapped in indigo. Don't let the pretty color distract you from the serious hardware. #BirdOfTheDay #Blue #BLGR #birding 1355
Peter Repetti @monstera999.bsky.social · 27/03/2026Every waterfowl bath seems to go the same way: dunk, preen, stretch, flap. If you see a Mute Swan working through its ablutions, just wait. The finale is coming. #BirdOfTheDay #WingsOpenNotFlying #MUSW #birding 0312
Peter Repetti @monstera999.bsky.social · 26/03/2026A Fox Sparrow's breast chevrons are (likely) a reaction-diffusion pattern; melanin pulses during feather growth, unfurling into V-shapes as the barb ridges spiral out of the follicle. Same math Turing described in 1952. #BirdOfTheDay #speckled #FOSP #birding 3291
Peter Repetti @monstera999.bsky.social · 25/03/2026Great Blue Heron on a post, mid-yawn, showing off its vivid orange gape that you don't see when the beak is closed. Even dinosaurs need to stretch. Durham, NC. #BirdOfTheDay #OpenBeak #GBHE #birding 2404
Peter Repetti @monstera999.bsky.social · 24/03/2026Turdus migratorius -- for some, but in NC, they never leave. We get these colors year-round: black velvet head, burnt-orange breast, bill like a shard of gold. The beautiful American Robin, so common and so underrated. #BirdOfTheDay #tricolour #YearRound #AMRO 3323
Peter Repetti @monstera999.bsky.social · 23/03/2026Great Egret conducting a full feather audit where every plume is accounted for, inspected, and zipped. Durham, NC. #BirdOfTheDay #Preeners&Scratchers #GREG #birding 1386
Peter Repetti @monstera999.bsky.social · 22/03/2026White-throated Sparrows migrate from the spruce forests of Canada to winter across the Southeast USA. They've been in Durham NC since October - but not for much longer. #BirdOfTheDay #Migratory #WTSP 2332
Reposted by Peter RepettiLiz Haswell @ehaswell.bsky.social · 20/03/2026Weeping to see the entire multicellular plant lineage reduced to a guard cells, and those a tiny afterthought in the corner! Nobody puts plants in the corner!! 5184
Peter Repetti @monstera999.bsky.social · 20/03/2026This Barred Owl fledgling dove from a tree to pounce on something in the leaf litter. It missed, but then immediately struck a sunning pose and cooly stared at me, "I meant to do that." Durham, NC. #BirdOfTheDay #Grounded #BAOW #birding 16610
Peter Repetti @monstera999.bsky.social · 19/03/2026Mourning Dove couple surveying the neighborhood from their mossy rooftop. They mate for life, and seem to have found their forever home. Durham, NC. #BirdOfTheDay #MarriedCouples #MODO #birding 2283
Peter Repetti @monstera999.bsky.social · 18/03/2026Purple Sandpiper in its element -- wedged between rockweed and barnacles, right where the tide meets the stone. Barnegat Light, NJ. #BirdOfTheDay #LandMeetsWater #PUSA #birding 2367
Peter Repetti @monstera999.bsky.social · 16/03/2026Very serious bathing commitment from this Canada Goose. Backlit water droplet splash chaos in shaft of light at golden hour. Durham, NC. #BirdOfTheDay #Splash #CANG #birding 1243
Peter Repetti @monstera999.bsky.social · 15/03/2026December truce. These Eastern Bluebirds grew up together and still share the mealworm feeder - for now. A few weeks later, the peace ends and they start claiming territories and nesting sites for spring, and my yard is really only big enough for 2 pairs. Durham, NC. #BirdOfTheDay #Feeders #EABL 1241
Peter Repetti @monstera999.bsky.social · 14/03/2026Can't go wrong for #GreyDay when you've got "gray" right in your name, spelling differences aside. Gray Catbird deep in the summer elderberry stash. July 2025, Durham, NC. #BirdOfTheDay #GRCA #birding 1202
Peter Repetti @monstera999.bsky.social · 12/03/2026"Sorry, no time to sing for you today — gotta go!" This Song Sparrow had other audiences to perform for. #BirdOfTheDay #SongBirds #SOSP 0131
Peter Repetti @monstera999.bsky.social · 10/03/2026These three American Crows are always together. Mated pair and a yearling? Three siblings? With corvids, the family politics are real but the loyalty is too. Sandy Creek Park, Durham, NC. #BirdOfTheDay #Corvidae #AMCR 1120
Peter Repetti @monstera999.bsky.social · 08/03/2026Barred Owl portrait. Stunning raptor, sure. But zoom in on those eyes. That's a parent of two who hasn't slept since fledging season, and has been up all "night," again. My backyard, Durham, NC. September 2024. #BirdOfTheDay #Photogenic #BAOW #BADO 1242
Peter Repetti @monstera999.bsky.social · 07/03/2026A Great Egret and its consultant, agreeing on the next move. Sandy Creek Park, Durham, NC. #BirdOfTheDay #StandingInWater #GREG 5465
Peter Repetti @monstera999.bsky.social · 06/03/2026Boat-tailed Grackle serving iridescent blue-black on the shoreline runway. No stylist. No agent. Just fierce main character energy, a beach and that swishy tail. Werk it! Sunset Beach, NC. #BirdOfTheDay #SteppingOut #BTGR 4486
Peter Repetti @monstera999.bsky.social · 04/03/2026Female Prothonotary Warbler, bill stuffed with moss destined for a cozy old woodpecker hole. Most eastern warblers weave open nest cups, but the PROW is the only one that chooses already-excavated cavities, preferably over standing water. #PROW #NestBuilders #BirdOfTheDay alt. 2180
Peter Repetti @monstera999.bsky.social · 03/03/2026A face built for the night shift. Yellow-crowned Night-Herons have rod-dense retinas tuned for low light, a bill heavy enough to crack crab carapaces, and the patience to stand motionless until something moves. #YCNH #BirdOfTheDay #SideView 2211
Peter Repetti @monstera999.bsky.social · 24/02/2026This isn't just a power pose. Turkey Vultures drop body temp overnight to save energy, then spread their wings in the AM to reboot: solar-heating flight muscles, UV-killing feather bacteria, baking off parasites. This "horaltic" pose is maintenance and power. #TUVU #PowerPose #BirdOfTheDay 2181
Peter Repetti @monstera999.bsky.social · 24/02/2026Vascular plants and mosses both produce Fibonacci-like spiral phyllotaxis, but diverged 450MYA. One uses auxin transport across a multicellular meristem to get the shape, the other does so via a single cell dividing such that new walls avoid oldest neighbors. Convergent evolution or deep homology? 111
Peter Repetti @monstera999.bsky.social · 16/02/2026She's not migrating. Cardinals don't use torpor; they depress nighttime body temp ~1.3°C, saving an estimated 10-16% on energy. In winter, diet shifts from insects to seeds. Fat reserves hit 3x summer levels. Puffed plumage traps warm air. Brrrrr. #NOCA #WinterSurvivors #BirdOfTheDay 1231
Peter Repetti @monstera999.bsky.social · 14/02/2026This Barred Owl is still drying off after a successful crayfish hunt. Some apparently eat so many that their underwing feathers can turn pink (!) from the carotenoids, like a flamingo. The most opportunistic owl in North America; 85+ prey taxa documented. #BAOW #portrait #birdOfTheDay 2160
Peter Repetti @monstera999.bsky.social · 13/02/2026Hooded Mergansers can change the refractive properties of their eyes to hunt underwater by sight. Built-in goggles via their transparent nictitating membrane. These two males are sizing each other up topside, but the real action is below the surface. #HOME #DivingForFood #BirdOfTheDay 1150
Reposted by Peter RepettiSquatlo Bob @squatlobob.bsky.social · 12/02/2026My #BirdOfTheDay offering is this male bluebird feeding his mate, a mating ritual seen regularly in the spring in middle Tennessee. #birds #canonbirdphotography #wildlife #BirdOfTheDay #bluebird 2517
Peter Repetti @monstera999.bsky.social · 12/02/2026Beak crammed with every squishy invertebrate it could find. Maximizing prey per trip, minimizing flight time to the nest. The bill-loading strategy: efficiency over elegance. Parents of all sorts will recognize this energy math. #AMRO #Birds&Bugs #BirdOfTheDay 2151
Peter Repetti @monstera999.bsky.social · 09/02/2026How do you find a gravity-sensing system nobody knew existed? First, knock out all 4 Arabidopsis LAZY genes so the plants can't stand up. Then, mutagenize thousands of those plants, and look for the one that pops back up! One aa change (S149F in SLQ1), and a whole new pathway emerges. #gravitropism 120
Peter Repetti @monstera999.bsky.social · 09/02/2026The fungal immune system runs on the same protein families as your innate immunity: NLR sensors, TIR signaling, gasdermin pore-formers. The pathways cluster in 2-3 gene operons, echoing bacterial defense islands. Billion-year-old toolkit, still in production.nature.comRegulated cell death in fungi from a comparative immunology perspective - Cell Death & DifferentiationCell Death & Differentiation - Regulated cell death in fungi from a comparative immunology perspective 131