Protein polymer scaffolds composed of death fold (DF) proteins are critical to the formation of signalosomes in immune signaling. The biophysical properties that these polymeric scaffolds require for ...

Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.

Protein design has focused primarily on the design of ground states, ensuring they are sufficiently low energy to be highly populated[1][1]. Designing the kinetics and dynamics of a system requires, i...