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Martha Klovstad

@mklovstad.bsky.social
54 followers 108 following 22 posts

BioPharma consultant focused on pulmonary hypertension, obesity, and heart failure #CardioSky #PulmSky. Minneapolis and public school believer #NokomisLife. Lover of dogs and nature.

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Martha Klovstad @mklovstad.bsky.social · 18/06/2025
157 House of Representatives members signed an amicus brief calling on the First Circuit to uphold a block on the NIH's planned cap on indirect cost reimbursements. Did your representative sign? In MN, only Angie Craig, Betty McCollum, and Kelly Morrison signed. endpoints.news/wp-content/u...
endpoints.news
Members of Congress oppose NIH's payment cut plan, urge appeals court to maintain block
A group of lawmakers opposes NIH's indirect cost reimbursement cap in appeals court, supporting states and universities against the Trump administration's 15% rate limit plan.
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Reposted by Martha Klovstad
Endpoints News @endpts.com · 01/04/2025
"FDA as we know it is finished," the agency's former commissioner lamented as the agency he once led is gutted by the new administration. Follow the developing story: endpts.com/firings-swee...
endpts.com
Firings sweep across FDA as former leaders lament drug agency's gutting
Mass firings and forced resignations swept through the FDA on Tuesday, as part of thousands of planned job cuts at federal health agencies being implemented by the Trump administration.
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Reposted by Martha Klovstad
Eric Topol @erictopol.bsky.social · 01/04/2025
How I will remember April Fools' Day 2025. Reckless. My heart is out for these dedicated folks at NIH, FDA and CDC www.statnews.com/2025/04/01/h...
statnews.com
HHS starts layoffs of thousands of workers across its agencies
Layoff notices began arriving early Tuesday for thousands of employees of HHS and its subsidiary agencies, with as many 10,000 workers potentially expected to be hit by the cuts.
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Martha Klovstad @mklovstad.bsky.social · 28/02/2025
Yes! endpts.com/infectious-d...
endpts.com
Exclusive: Infectious disease doctors consider 'mini-ACIP' if RFK erodes CDC vaccine panel
Infectious disease professionals, bracing for an overhaul of the CDC's vaccine advisory group, are in discussions to stand up a parallel committee of experts outside of government.
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Reposted by Martha Klovstad
Prof Christina Pagel @chrischirp.bsky.social · 24/02/2025
🧵Delighted to share a new guest post by Dr Anne Toomey on **8 things scientists can do right now to stand up for science in the US** Thread of her *evidence-based* actions follows, whole post here christinapagel.substack.com/p/eight-thin... 1/11
christinapagel.substack.com
Eight things scientists can do right now to stand up to the Trump administration’s attacks on research, public health, and the environment
A guest post by Dr Anne Toomey, author of the book "Science with Impact: How to Engage People, Change Practice, and Influence Policy".
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Martha Klovstad @mklovstad.bsky.social · 24/02/2025
"Though BioMarin is a global organization... the U.S. remains a vital source of innovative research that pharma companies ultimately turn into medicines. We're hoping that pipeline of good ideas, which often comes from NIH-funded research, doesn't dry out.” Thank you for your courage BioMarin.
fiercebiotech.com
As BioMarin searches for 'clever science,' its R&D chief warns innovation could be hit by NIH fund drought
A slimmed-down BioMarin started the new year with a bang, hitting the annual J.P. | A slimmed-down BioMarin started the new year open for business, seeking to leverage its unique skillset to strike de...
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Martha Klovstad @mklovstad.bsky.social · 20/02/2025
So hoping this happens in Minneapolis standupforscience2025.org
standupforscience2025.org
STAND UP FOR SCIENCE
March 7, 2025. Washington DC and Nationwide. Because Science is for everyone.
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Martha Klovstad @mklovstad.bsky.social · 19/02/2025
PHAR registry study shows SELF-REPORTED medication non-adherence in PAH/CTEPH of only 6.1%. Male sex and social health determinants had largest impact. #pulmonaryhypertension #pulmsky
pubmed.ncbi.nlm.nih.gov
Medication Non-Adherence in Patients with Pulmonary Arterial Hypertension: The Pulmonary Hypertension Association Registry (PHAR) - PubMed
<span><b>Rationale</b> Pulmonary arterial hypertension (PAH) is associated with significant morbidity and mortality. The extent of medication non-adherence in PAH is uncertain and may be linked to adv...
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Martha Klovstad @mklovstad.bsky.social · 18/02/2025
Community warms my heart. We have another school closure day due to negative double digit temps. Parents and pastors at my small neighborhood church just banded together to provide open gym for our kids and neighborhood kids so we don't all go insane on day 5 off of school while juggling work.
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Martha Klovstad @mklovstad.bsky.social · 17/02/2025
Unbelievable that device and drug reviewers and facility inspectors were cut. We need more of them, not less. Read Bottle of Lies and then tell me we should cut inspectors. Meet some advanced heart failure patients and then tell me we don't want on-time device approvals and on-market safety reviews.
statnews.com
Drug inspectors, AI experts, maternal health workers: Trump’s health agency cuts are far-reaching
In interview after interview with STAT, those who were fired from federal health and science agencies, along with officials who remain, argued the cuts would be deeply felt.
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KaminskiMed @kaminskimed.bsky.social · 16/02/2025
When the next pandemic hits us, remember - our surveillance system did not fail - it was SABOTAGED. A quarter of the staff coordinating USDA’s National Animal Health Laboratory Network program were fired. Do not say you did not know. www.politico.com/news/2025/02...
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Jack Iwashyna @iwashyna.bsky.social · 12/02/2025
Nice reporting by @berkeleyjr.bsky.social “Direct cost is the groceries," Golden said. "Indirect costs are the money you need to have a refrigerator and to pay your electric bill so that the milk and eggs don’t go bad.” www.nbcnews.com/health/healt...
nbcnews.com
NIH cuts could stall medical progress for lifesaving treatments, experts say
Although the funds don’t directly support patient care, they help keep basic operations afloat, such as keeping the lights on and the labs clean.
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JACC Journals @jaccjournals.bsky.social · 11/02/2025
#THT2025 #JACCHF LBCT: In patients with #heartfailure & #LVEF >40%, APTURE shunt confirmed acceptable safety profile with improvements in HF symptoms, #QoL, & functional capacity without negatively affecting right & left heart function after 2 years, regardless of PVD www.jacc.org/doi/10.1016/...
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Martha Klovstad @mklovstad.bsky.social · 11/02/2025
Risk score (PVD-B65) development for Group 3 PH - 42% COPD, 32% non-CPFE PF, 13% CPFE in cohort #PulmSky
pmc.ncbi.nlm.nih.gov
Development of the pulmonary fibrosis, pulmonary vascular resistance, six minute walk distance, B-type natriuretic peptide, age (PVD-B65) risk score for patients with chronic lung disease and pulmonar...
Pulmonary hypertension (PH) confers increased mortality in patients with chronic lung disease, yet there remains a lack of validated risk assessment tools to prognosticate these patients. We aimed to ...
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Martha Klovstad @mklovstad.bsky.social · 11/02/2025
As outcry builds over Trump cuts to NIH payments, drugmakers are MIA www.statnews.com/2025/02/11/n... via @statnews.com
statnews.com
As outcry builds over Trump cuts to NIH payments, drugmakers are MIA
Drugmakers — major beneficiaries of NIH-backed university research — have been largely silence on the Trump administration's cuts to agency research payments.
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Reposted by Martha Klovstad
Jack Iwashyna @iwashyna.bsky.social · 10/02/2025
More great reporting from @statnews.com www.statnews.com/2025/02/10/n...
statnews.com
22 states sue to block Trump administration cuts to NIH research payments
Attorneys general sued the Trump administration to block a NIH decision that would slash grant payments for research overhead
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Reposted by Martha Klovstad
STAT @statnews.com · 09/02/2025
The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research.
buff.ly
The NIH’s drastic cut to indirect cost rates is a critical threat to U.S. research infrastructure
The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research.
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Reposted by Martha Klovstad
Scott Hadland, MD @drscotthadland.bsky.social · 08/02/2025
If you are pro-life, I recommend calling Congress to voice concern. Yesterday’s NIH funding cuts are likely to halt research on: - New cancer drugs - Heart attack/stroke treatment & prevention - Interventions to help premature babies survive - Mental health treatment - Etc #MedSky #NIH #research
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Reposted by Martha Klovstad
Dr. Sven-Eric Jordt #TobRegSky @sejordt.bsky.social · 09/02/2025
#MedSky #EpiSky #addictionsci #policysky #polisky🧪🛟 And the brain drain begins: President of the German Max-Planck-Society states that applications from the US for science group leader positions have increased. Society will specifically target leading US researchers. www.spiegel.de/wissenschaft...
spiegel.de
(S+) Deutschland und Donald Trump: Max-Planck-Gesellschaft wirbt um US-Spitzenforscher
Ist Deutschland am Ende Nutznießer von Trumps Feldzug gegen die Wissenschaft? Die Max-Planck-Gesellschaft meldet viel mehr Bewerbungen aus den USA als früher. Präsident Patrick Cramer will dort geziel...
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Reposted by Martha Klovstad
Jack Iwashyna @iwashyna.bsky.social · 08/02/2025
I just texted my mom
Please consider calling your senators and Congressman
tonight to tell them to oppose this
Here is a script
This is xxxx
• My
address is XXX. I am writing because my sons are doctors and they have taught me how important health research is. The trump administration just proposed a new change in NIH indirect cost rates. I know that sounds like bureaucracy I should not have to care about. But without indirect costs being adequately reimbursed to universities, research will be impossible. This policy would gut research, making my grand children's lives shorter and sicker.
Please force the NIH to reinstitute the support for the university research that has saved so many lives and created so many jobs
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Colette Delawalla, PhD @cdelawalla.bsky.social · 09/02/2025
Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.
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Martha Klovstad @mklovstad.bsky.social · 09/02/2025
Gut-wrenching. I can't believe this isn't getting shouted from the rooftops, but I guess that was the point of killing biomedical research in the US with a Friday night memo.
nytimes.com
Trump Administration Cuts Put Medical Progress at Risk, Researchers Say
Grants from the National Institutes of Health come with additional money for overhead. A planned $4 billion cut would leave colleges with large budget gaps.
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Reposted by Martha Klovstad
Pearl Freier @pearlf.bsky.social · 08/02/2025
“Beijing assumes that Washington’s own policies will dismantle the foundations of U.S. global hegemony, even if it creates a lot of turbulence…in the process" -Yun Sun in Foreign Affairs below: www.foreignaffairs.com/china/chinas... #medsky #biosky
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Reposted by Martha Klovstad
Pearl Freier @pearlf.bsky.social · 06/02/2025
Thousands of FDA, CDC, HHS, NIH & other US federal health agency employees may be fired by executive order as soon as next week according to the WSJ and inside sources who spoke with them. Here's an unlocked link to the WSJ story: www.wsj.com/health/healt... #medsky #biosky
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Martha Klovstad @mklovstad.bsky.social · 06/02/2025
Unreal
nytimes.com
Dozens of Clinical Trials Have Been Frozen in Response to Trump’s USAID Order
The stop-work order on U.S.A.I.D.-funded research has left thousands of people with experimental drugs and devices in their bodies, with no access to monitoring or care.
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Minnesota Reformer @minnesotareformer.com · 29/01/2025
One-quarter of Minnesota households with children are food insecure, according to a statewide huger survey by @2harvest.bsky.social. minnesotareformer.com/briefs/one-q...
minnesotareformer.com
One-quarter of Minnesota households with children are food insecure • Minnesota Reformer
One-quarter of Minnesota households with children are food insecure, according to research released Wednesday by the nonprofit hunger relief organization Second Harvest Heartland. The food bank’s firs...
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Reposted by Martha Klovstad
Endpoints News @endpts.com · 29/01/2025
Eli Lilly is dropping its Phase 2 heart failure and kidney disease drug, volenrelaxin, citing a lack of clinical benefit.
endpts.com
Ahead of earnings, Lilly culls mid-stage drug for heart failure and chronic kidney disease
Eli Lilly is discontinuing a Phase 2 relaxin treatment candidate for heart failure and chronic kidney disease, a spokesperson for the company confirmed to Endpoints News.
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Martha Klovstad @mklovstad.bsky.social · 28/01/2025
Why are way less than half of PAH patients being seen at PH centers? pubmed.ncbi.nlm.nih.gov/39836217/
pubmed.ncbi.nlm.nih.gov
Location of Care Delivery for Pulmonary Arterial Hypertension in the United States - PubMed
A minority of US patients received PAH-specific prescription from a PH center. This potential guideline discordance warrants further exploration and may require guidelines to be revisited or the healt...
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Martha Klovstad @mklovstad.bsky.social · 28/01/2025
My heart goes out to so many but especially to all my past colleagues that are still doing grant-funded research
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Waggoner Lab @labwaggoner.bsky.social · 23/01/2025
Lysosome interaction with other organelles may be linked to pulmonary hypertension www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... @science.org
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Eric Topol @erictopol.bsky.social · 24/01/2025
Welcome immigrants from X interested in science to the friendlier skies of @bsky.app, as documented by a new @nature.com survey (but you already knew that 😉) "Bluesky is much better for science. There is much less toxicity, misinformation, and distractions." www.nature.com/articles/d41...
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Martha Klovstad @mklovstad.bsky.social · 24/01/2025
Last couple of weeks of PAH publications have some real gems, including this Chinese PAH epidemiology - great to see high-quality epi from China now being published in English pubmed.ncbi.nlm.nih.gov/39839629/
pubmed.ncbi.nlm.nih.gov
Long-term trends in the burden of pulmonary arterial hypertension in China and worldwide: new insights based on GBD 2021 - PubMed
The findings highlight the age-related burden of PAH in China, particularly affecting older populations and women. The projected stabilization of PAH metrics over the next decade underscores the need ...
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Martha Klovstad @mklovstad.bsky.social · 24/01/2025
Intriguing possibility for catching PAH early - Early research but encouraging jnm.snmjournals.org/content/66/1...
jnm.snmjournals.org
Targeting Fibroblast Activation Protein for Molecular Imaging of Fibrotic Remodeling in Pulmonary Arterial Hypertension
The purpose of this study was to investigate the feasibility of using 18F-labeled fibroblast activation protein inhibitor (FAPI) PET/CT in assessing the fibrotic remodeling of the pulmonary artery (PA...
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