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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 14/09/2026

Aurora Series® 5 has arrived: NEW CoreJet™ integrated emitter technology brings greater robustness & longevity to high-performance nanoflow proteomics unlocking the depth & sensitivity of Aurora for longer studies, higher throughput & routine everyday use. Explore: ionopticks.com/aurora-series-5

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Michael Sinden @mdsinden.bsky.social · 14/09/2026

Nine years of refining Aurora has led to this. Aurora Series 5 is here, making high-performance proteomics more robust, practical and feasible for everyday use. Proud of everyone who helped develop, test and launch it, and proud to be #teamIO. Go check out the new products!

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 12/09/2026

This recent @sciex.bsky.social technical note pairs IonOpticks’ Aurora® Ultimate™ 25 cm × 75 µm XS column with the ZenoTOF 8600 system and ZT Scan DIA 3.0: >13,600 protein groups and >290,000 precursors from 200 ng human, yeast & E. coli lysate injections with strong quantitative reproducibility.

sciex.com

Narrow-window scanning DIA for unbiased label-free quantitation: Improved protein group ratio accuracy with ZT Scan DIA 3.0 on the ZenoTOF 8600 system

This technical note describes label-free quantitation (LFQ) proteomics analysis of complex lysate digest mixtures using a narrow-window ZT Scan DIA 3.0 workflow on the ZenoTOF ...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 03/09/2026

IonOpticks continues to champion the global proteomics community by supporting the 25th Human Proteome Organization World Congress as a Bronze Sponsor. This year we are holding a breakfast seminar with guest speakers and complimentary breakfast and you're invited. ionopticks.com/our-event/io...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 30/07/2026

Maximising instrument utilisation on an Orbitrap Astral takes more than a fast instrument. For Dr Juan Liu, mass spec lab manager at @hhmi-science.bsky.social Howard Hughes Medical Institute, the right column made it possible. Learn more about Aurora® Ultimate™ 25x150: bit.ly/4ykTWGE

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 24/07/2026

Following the opening of its new UK facility, IonOpticks is expanding its US presence with local stock in Pennsylvania, faster fulfilment, North America-based applications support and dedicated regional expertise. Read the full release.

ionopticks.com

IonOpticks announces expanded US presence to bring products and support closer to North American researchers

IonOpticks today announces a further expansion of its global presence, with strengthened operations and customer support across the United States.The expansion improves access to IonOpticks’ advanced ...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 23/07/2026

IonOpticks is proud to officially open a new purpose-built facility at Milton Park in Oxfordshire UK, expanding its global presence with local order processing, distribution, warehoused stock, commercial and scientific expertise, and a dedicated applications development laboratory. Read online:

ionopticks.com

IonOpticks opens UK-based facility to bring faster access, local expertise and application support closer to European researchers

IonOpticks' new facility, based in the Milton Park scientific precinct south of Oxford, brings together order processing and distribution, locally warehoused stock, administrative support, commercial ...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 22/07/2026

Great to be at #SCP2026 at @northeasternu.bsky.social last week, witnessing the remarkable momentum in single-cell proteomics. Across countless fantastic oral presentations, we’re seeing where SCP is heading: deeper characterisation, higher throughput, & better quantitation across diverse workflows.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 20/07/2026

We're pleased to welcome Dr Denise Tran to IonOpticks as Applications Scientist, based in Oxford, UK. She'll support researchers with LC-MS proteomics workflows, applications and method development, and help optimise performance, troubleshoot challenges and get the best from IonOpticks columns.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 15/07/2026

Great to be at #BSPR2026 in Hinxton this week, supporting the UK's key proteomics gathering. On Monday, conference conversations continued at our Peaks & Pints event - it's been a pleasure connecting with so many of you. If you're still here today, stop by - we'd love to hear what you're working on.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 15/07/2026

We're excited to welcome Dr Anuar Makhmut to IonOpticks as a Field Application Specialist, supporting researchers across Europe. He'll be working directly with research teams to design, optimise, and implement proteomics workflows suited to their goals. It’s fantastic to have him on board.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 14/07/2026

As a mass spec lab manager at @hhmi-science.bsky.social Howard Hughes Medical Institute, Dr Juan Liu's focus is on pushing proteome coverage deeper. After switching to the Aurora® Ultimate™ 25x150 XT for both general proteomics and phosphoproteomics workflows, the results speak for themselves:

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 14/07/2026

De novo antibody sequencing typically demands 4–6 parallel protease digestions to adequately cover hypervariable CDR regions. Pañeda et al. challenge that paradigm entirely. LC-MS/MS used an Aurora® Elite™ 15×75 XS column, an UltiMate 3000, and a SCIEX ZenoTOF 7600. Learn more: bit.ly/4eshTEd

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 07/07/2026

Janssens et al. benchmark the timsUltra AIP for SCP: using an Aurora® Elite™ 15×75 CSI column + nanoElute 2, the team achieved a >2× increase in protein IDs at the single-cell level, with ~50% of the detected proteome identified exclusively on the new instrument. Learn more: bit.ly/4gF6Tog

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 01/07/2026

When your research involves thousands of glycoproteoforms, you need columns you can count on. To Dr. Tim Veth, postdoctoral researcher at the University of Washington, one Aurora column lasting several months of high performance was all the evidence he needed. Learn more: bit.ly/4nrMzad

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 30/06/2026

Day 1 of the SEMM Workshop "The Proteomics Revolution: Advancing Science and Society" is wrapped up, and it's been a brilliant start to what promises to be a memorable few days in Milan. If you're here, come find us - Britta and Darren would love to connect.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 30/06/2026

Zhemkov et al. applied an exploratory, global protein identification approach across a 60-day iPSC-to-motor neuron differentiation protocol, using Aurora® Rapid™ 5x75 CSI columns on a timsTOF Ultra 2 to achieve ~20% greater sensitivity and ~175% more low-abundance protein detections. bit.ly/4aJKPFi

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 25/06/2026

We're thrilled to welcome Dr Yana Demyanenko to the IonOpticks team as an Application Scientist, based in the UK. She'll help researchers get the most out of their LC-MS proteomics workflows. Outside the lab, Yana is an avid DIYer, making things from cakes to dresses to garden landscapes.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 25/06/2026

What happens to a neuron as it develops an Alzheimer's tangle? Single-cell proteomics has answers in the June 2026 Publication Digest | Plus glycogen ubiquitination, stress granule proteomics in single cells, and plasma workflow benchmarking with Aurora Series® columns Learn more: bit.ly/4oMipQV

bit.ly

What happens to a neuron as it develops an Alzheimer's tangle?

Single-cell proteomics has answers in the June 2026 Publication Digest | Plus glycogen ubiquitination, stress granule proteomics in single cells, plasma workflow benchmarking with Aurora Series® Narro...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 24/06/2026

Most virtual cell models tell you what a cell is instructed to do, not what it really does. That's the gap Dr Zilu Ye is working to close. In our spotlight, Zilu talks single-cell proteomics, the result nobody believed, & why the biggest breakthroughs may arrive sooner than expected. bit.ly/4b8dOCS

bit.ly

From proof of concept to platform: How Dr. Zilu Ye is scaling single-cell proteomics for the real world

Dr. Zilu Ye, Principal Investigator at the Institute of Systems Medicine at the Chinese Academy of Medical Sciences, has spent his career developing mass spectrometry–based proteomics tools that don’t...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 23/06/2026

Foiani et al. from the @ukdri.ac.uk shed light on Alzheimer's disease brain tissue using single-neuron proteomics, pairing an Aurora® Elite™ 15×75 CSI column with an Evosep One and timsTOF Ultra 2. Learn more: bit.ly/4xvASoJ

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 23/06/2026

A recent @sciex.bsky.social technical note benchmarks the ZenoTOF 8600 system for short-gradient, high-throughput label-free quantitative (LFQ) proteomics. Chromatography performed on an ACQUITY UPLC M-Class paired with an Aurora® Ultimate™ 25x75 XS column for nanoflow analyses. bit.ly/4vZajqn

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 18/06/2026

Dr @mari-mardamshin.bsky.social, postdoctoral fellow in Assoc Prof Emma Lundberg's lab at Stanford, works at the frontier of spatial proteomics, where column robustness is crucial - especially with low-input samples. Aurora Series® columns help make that work possible. Learn more: bit.ly/3IELayn

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 17/06/2026

A new @sciex.bsky.social technical note demonstrates significant improvements in label-free quantitation (LFQ) proteomics using ZT Scan DIA 3.0 on the ZenoTOF 8600 system, which was paired with an ACQUITY UPLC M-Class System and an Aurora® Ultimate™ 25x75 XS column. Learn more: bit.ly/4oAy45V

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 16/06/2026

On the final afternoon of the 74th MSSJ Annual Conference on Mass Spectrometry in Yokohama, our Sweets Seminar wrapped up with 80 attendees - a wonderful turnout, and a great energy to end the conference on. Even if it was testing the limits of Fabrice’s conversational Japanese!

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 15/06/2026

Davison et al. coupled nanocapillary sampling with LC-MS for the first time to profile stress granule proteins from individual live cells, bypassing the limitations of bulk purification. Used Vanquish Neo, Aurora® Rapid™ 8×75 XT column, & Orbitrap Astral. Learn more: bit.ly/3PYy6HQ

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 15/06/2026

Last week, our UK team had the pleasure of hosting Fintiede Solutions Solutions, IonOpticks' local distribution partner, in person at our new facility. Of course, no meeting is complete without a proper spread, including the cultural exchange that is sharing a jar of Vegemite. Or is it Marmite?

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 10/06/2026

Luke Gamon, Asst Prof at @ucph.bsky.social, built a spatial proteomics workflow from standard lab equipment: PCR tubes, centrifuges, basic plastics. When a single Aurora column can handle 2,500 injections and still perform, that kind of longevity changes what's feasible. Learn more: bit.ly/4ulX2XL

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 10/06/2026

Rebeca Kawahara was waiting on a competitive fellowship outcome, settled in Australia with two young children. An unexpected offer arrived: to establish a Glycoproteomics Lab in Japan. She took it. 'Sometimes the biggest growth comes from stepping into the unknown.' Read her story: bit.ly/4oiKhM4

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Written in sugar: Dr Rebeca Kawahara on bringing the glycan code into medicine

Dr Rebeca Kawahara, a glycoproteomics researcher with dual affiliations at Griffith University’s Institute for Biomedicine and Glycomics and the Institute for Glyco-core Research (iGCORE) at Nagoya Un...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 09/06/2026

Under the warm glow of the San Diego skyline, we welcomed over 230 of you to Deck655 for IonOpticks' annual #ASMS2026 User Event to close out a massive week of science and innovation. We look forward to inviting you to our next one at #HUPO2026 in Singapore. Photos from the night: bit.ly/4afec23

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 09/06/2026

NoPro-clipping: a new @komanderlab.bsky.social nanoflow LC-MS/MS workflow from @marcojochem.bsky.social et al. using an Aurora® Elite™ 15×75 column + Orbitrap Eclipse, Vanquish Neo detects ubiquitination of glycogen, glycerol & spermine in cells & tissues via targeted PRM. Learn more: bit.ly/3PYs222

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 05/06/2026

Next week, Fabrice heads to Yokohama for the 74th MSSJ Annual Conference on Mass Spectrometry, co-exhibiting with our Japanese distribution partner AMR at Stand 17. We're also hosting a Sweets Seminar on Friday 12 June at 02:00pm - a great chance to hear from an expert speaker and enjoy some treats.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 04/06/2026

Please join us in welcoming Mike Baynham to the IonOpticks team as our new Global Product Manager, joining our Global Commercial team. We look forward to the insight, expertise and customer focus Mike will bring as we continue enhancing our product portfolio for researchers around the world.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 04/06/2026

What a way to start this morning. We were pleased to see the room being full, the curiosity palpable, and the discussion lively at our #ASMS2026 breakfast seminar. If your question wasn't answered, join us at the IonOpticks booth, and hopefully you'll cross paths with the speakers on the floor too.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 03/06/2026

Grateful to everyone who stopped by Haley and Greta’s NanoShield® poster this morning at #ASMS2026 - the conversations were fantastic. Swing by booth 623 and we'd love to walk you through how NanoShield® delivers near-direct-injection performance while keeping your workflow healthy long-term.

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Michael Sinden @mdsinden.bsky.social · 03/06/2026

I’m hiring a Scientific Marketing Lead, LC-MS Proteomics, based in Melbourne. A rare blended role for someone who sits between science and marketing, ideal for a PhD candidate or researcher looking to move from the lab bench to industry. Details: lnkd.in/e5ZTAFew

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 02/06/2026

A great moment at the Thermo #ASMS2026 user meeting as Mark Larance from @sydney.edu.au highlighted the performance of Aurora® Elite™ 15x75 XT columns in his SCP workflow. Great to see this workflow pushing what's possible in high-throughput single-cell analysis.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 01/06/2026

What a start to #ASMS2026! The welcome reception brought a lively crowd to the IonOpticks booth, with strong interest from night one. Our team loved seeing familiar faces and new connections, and we’re keen to keep the conversations going as the week progresses.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 01/06/2026

Kicking off the week of #ASMS2026, Haley and Zac joined the Bruker eXceed Symposium, a brilliant one-day deep dive into cutting-edge MS innovation ahead of the main conference. During the breaks, it was great to see our NanoShield® trap column drawing plenty of curious eyes. #MassSpectrometry

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 01/06/2026

And we're off! #ASMS2026 begins tonight, and we’re excited to be back in San Diego for the biggest mass spec event of the year. Visit #teamIO at booth 623, welcome Mike Baynham, see our new NanoShield C18 trap column, grab some signature swag and register for our Wednesday breakfast seminar.

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 29/05/2026

Thank you to everyone who joined Dr @brendonseale.bsky.social's IonOpticks Insights webinar on scaling core facility proteomics. You can still register to watch it on demand, along with helpful bonus materials, which you can find under "Additional Resources": bit.ly/3QRnp9T

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 29/05/2026

This Thermo Scientific tech note tackles one of immunopeptidomics' toughest challenges: getting meaningful depth from low-level, precious clinical material. The Orbitrap Astral Zoom was paired with a Vanquish Neo and an Aurora® Ultimate™ 25×75 XT column. Read the full tech note: bit.ly/4xeEdZt

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 29/05/2026

We're delighted to welcome @amandalsmythers.bsky.social from the Gygi Lab at Harvard Medical School and Dana-Farber Cancer Institute to our #ASMS2026 breakfast seminar. She'll bring her expertise in phospho DIA on the Astral. Wednesday June 3, 7:00am Breakfast provided Register now: bit.ly/4dvarXl

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 28/05/2026

We're pleased to welcome Denys Oliinyk from the Mann Lab to our #ASMS2026 breakfast seminar. He'll join a panel discussion spanning single-cell, phospho, and DVP - and what good separation unlocks across these fields. Wednesday, 3 June, 07:00am. Breakfast provided. Register now: bit.ly/4dvarXl

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 27/05/2026

Excited to have @slavov-n.bsky.social as a speaker at our #ASMS2026 Breakfast Seminar. He'll bring his single-cell perspective to a broader conversation about what good separation enables across modern proteomics workflows. Wednesday June 3, 07:00am Breakfast provided Register now: bit.ly/4dvarXl

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 25/05/2026

Traps have long been seen as a trade-off: more robustness, less performance. But what if that compromise was never inevitable? In this opinion piece, Dr Jarrod Sandow explores how NanoShield® C18 trap columns are helping proteomics workflows become both resilient and high-performing:

ionopticks.com

Traps: The column companion we misunderstood

Proteomics is evolving rapidly, and as we push toward deeper coverage, higher throughput, and more demanding applications, the expectations placed on our workflows will only increase. Meeting those ex...

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 23/05/2026

In highly sensitive immunopeptidomics, confidence in your column matters. Professor Tony Purcell shares how Aurora Series columns support demanding LC-MS workflows with the robustness, sensitivity, longevity and reproducibility researchers need, across Bruker timsTOF and SCIEX ZenoTOF systems.

youtube.com

IonOpticks and The Purcell Lab: From collaboration to innovation.

YouTube video by IonOpticks

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Reposted by Michael Sinden

IonOpticks @ionopticks.com · 25/05/2026

At #ProteoVilamoura2026, @sciex.bsky.social's Mario Armelao delivered an impressive talk showcasing the low-input capabilities of the ZenoTOF 8600 system, when combined with the Evosep Eno paired with Aurora® Elite™ XS columns.

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