Sign in

Amanda Smythers

@amandalsmythers.bsky.social
1.4K followers 1K following 149 posts

PhD, Analytical Chemistry • Postdoc in Spiegelman, Chouchani, & Gygi labs, Dana Farber Cancer Institute & Harvard Med School • #TeamMassSpec #Proteomics #MolecularMetabolism

PostsRepliesMedia
Amanda Smythers @amandalsmythers.bsky.social · 04/06/2026
#ASMS2026
040
Amanda Smythers @amandalsmythers.bsky.social · 03/06/2026
Hey #ASMS2026! Come hang out with me at poster 692 and Golgi will give you this cool shirt!
050
Amanda Smythers @amandalsmythers.bsky.social · 29/05/2025
I’m sad to share that my father died yesterday after a 5 month battle with pancreatic cancer. It’s a horrific disease. So grateful for my colleagues at the @danafarber.bsky.social for helping me through this process. www.cunninghamfuneralhome.net/obituaries/M...
cunninghamfuneralhome.net
Obituary information for Mark Allan White
View Mark Allan White's obituary, contribute to their memorial, see their funeral service details, and more.
8140
Reposted by Amanda Smythers
US HUPO @us-hupo.org · 26/05/2025
Don't Miss Out - TOMORROW - it's an interactive proteomics seminar series! The CNPN x US HUPO Spotlight Series Webinar brings you cutting edge proteomics research from leading Canadian and US scientist. Register NOW: ow.ly/lSY150VNhpI
042
Reposted by Amanda Smythers
Pete Buttigieg @petebuttigieg.bsky.social · 23/05/2025
America cannot long remain free, nor first among nations, if it becomes the kind of place where universities are dismantled because they don't align politically with the current head of the government.
14424769011267
Amanda Smythers @amandalsmythers.bsky.social · 23/05/2025
Rough time in our house as we said goodbye to our cat yesterday. 12 years was not nearly enough.
3100
Amanda Smythers @amandalsmythers.bsky.social · 21/05/2025
Busy couple of days! Kiddo scored her first goal in Boston, me and the hubs saw Tina Fey and Amy Poehler on tour, and Jewish heritage night at the Sox marked the coldest baseball game of my life 😅 Just a quintessential New England weekend 🤣
090
Reposted by Amanda Smythers
Cathy Gao-Howard MD MS @catgaohow.bsky.social · 18/05/2025
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
181458598
Reposted by Amanda Smythers
Sam Wang @samwang.bsky.social · 17/05/2025
This is completely false. Even the largest university endowment cannot sustain large-scale scientific research. In my 25 years at my school, the most monumental research fund drive raised $325M in *total*. Federal research here costs $200M per *every year*. This is an extinction-level event.
351316383
Reposted by Amanda Smythers
Chris Ashwood @cashwood.proteaglyco.com · 13/05/2025
Disappointing to see, across both parties. Sciex is no longer providing funding for Skyline/Proteowizard as part of the multi-vendor agreement to keep Skyline supported across all major vendors. I can see the arguments from both sides, just a shame it's resulted in this.
Transcribed text:
Skyline Targeted Mass Spec Environment

Dear Skyline Users,


I would like to thank Agilent, Bruker, Shimadzu, Thermo Fisher, and Waters for their continued funding support for the Skyline project this year.  This industry/government/university partnership allows all of us to maximize the value of our efforts to provide better mass spectrometry tools to the field. In the current federal funding environment, industry support is critical to maintain our work.


Some instrument vendors, such as SCIEX, have not invested in the Skyline project this year. As a public university, we are limited in how we can support the private sector under state law.  We paused our work in Skyline and ProteoWizard on support for SCIEX instruments to remain in compliance with state law. While we hoped SCIEX would resume its funding support of the Skyline project for use with their instruments, and respect their decision not to provide funding, we cannot continue our work to support SCIEX in Skyline or ProteoWizard without SCIEX funding. We have informed the ProteoWizard Foundation of this development.


As always, we look forward to seeing many of you at ASMS or our Skyline course at UW this summer. We thank all of you for your continued support.

Brendan MacLean,

Skyline Project Lead
6206
Amanda Smythers @amandalsmythers.bsky.social · 11/05/2025
Lucky 13 in the books today. ✨ Kiddo had a sleepover so we could enjoy this “hidden” cafe in Beacon Hill with enough champagne to give me proper rosy cheeks 🥰🥂
080
Reposted by Amanda Smythers
Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 09/05/2025
Now they are gutting NSF. This is radical destruction. The Trump goal is to end scientific research in America. Our sense is that few people, even inside the government, have actually grappled with this reality.
science.org
Exclusive: NSF faces radical shake-up as officials abolish its 37 divisions
Changes seen as a response to presidential directives on what research to fund
9287126
Reposted by Amanda Smythers
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 06/05/2025
The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n
628082
Reposted by Amanda Smythers
Max Kozlov @maxkozlov.bsky.social · 06/05/2025
FWIW, NIH had already silently barred Harvard and four other schools from receiving funds — and agency staff were forbidden from telling applicants and grantees about it. bsky.app/profile/maxk...
10485189
Amanda Smythers @amandalsmythers.bsky.social · 05/05/2025
These are truly unprecedented times for science, & I know several community members facing job loses. It would be incredibly helpful for those hiring in proteomics to post to our US HUPO job board so we can help our colleagues find new positions. Please share! us-hupo.org/US-HUPO-Job-...
us-hupo.org
US HUPO - Job Board
052
Amanda Smythers @amandalsmythers.bsky.social · 28/04/2025
So excited to see this work!
030
Amanda Smythers @amandalsmythers.bsky.social · 21/04/2025
My stomach (and heart) is satisfied ♥️
150
Amanda Smythers @amandalsmythers.bsky.social · 20/04/2025
Made a reservation at an Italian restaurant to break Passover tonight. I neeeeed noodles. No idea how my kiddo can do stuff like this- I feel like my stomach is full of matzah shaped boulders!
150
Reposted by Amanda Smythers
Nick Riley @nmriley.bsky.social · 18/04/2025
I still can't quite believe I am included in the 2025 Searle Scholars cohort. Feeling especially thankful for all who have supported me. I am most excited about the science @riley-research.bsky.social gets to pursue and the support this award provides for my group searlescholars.org/2025/04/14/s...
searlescholars.org
SEARLE SCHOLARS PROGRAM NAMES 15 SCIENTISTS AS SEARLE SCHOLARS FOR 2025
Members of the new class of Searle Scholars pursue ground-breaking research in chemistry and the biomedical sciences. Each receives an award of $300,000 in flexible funding to support his, her, or …
3666
Reposted by Amanda Smythers
Jonathan Lambert @jonlambert.bsky.social · 18/04/2025
Hearing from sources that grant terminations are starting now, likely targeting grants aimed at broadening participation of underrepresented groups in science.... which congress explicitly asks NSF grants to do.
34228
Reposted by Amanda Smythers
Malinda Lo @malindalo.bsky.social · 14/04/2025
Harvard redid its whole homepage to push back against the administration’s demands. I mean, this is just a website but I think it’s kind of a great PR move: www.harvard.edu
harvard.edu
Harvard University
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders who make a difference globally.
11269481487
Amanda Smythers @amandalsmythers.bsky.social · 14/04/2025
Very glad that Harvard will fight. History is not kind to those who give up their rights freely.
020
Amanda Smythers @amandalsmythers.bsky.social · 13/04/2025
I hope everyone celebrating has a wonderful Passover! We are praying for an end to warfare, our hostages to return, and injustice to end- in the US and elsewhere. Grateful to be with family and to enjoy these traditions with my kiddo.
050
Reposted by Amanda Smythers
Christian Frezza @frezzalab.bsky.social · 11/04/2025
www.nature.com/articles/s42... Metabolites are not genes. repeat, please!
nature.com
Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics - Nature Metabolism
Pathway analysis, originally developed for gene expression data, has been adapted for metabolomics. However, owing to the unique characteristics and constraints of metabolites compared with genes, pat...
09131
Reposted by Amanda Smythers
Nick Riley @nmriley.bsky.social · 08/04/2025
Feeling fortunate for the opportunity to thank the many mentors who have supported me and to highlight the outstanding scientists in @riley-research.bsky.social. Excited to keeping working together as a group and with the bigger #glycotime and #TeamMassSpec communities to advance glycoscience
4425
Reposted by Amanda Smythers
Lawrence Kazak @kazaklab.bsky.social · 07/04/2025
Speaker Spotlight: Bruce Spiegelman @spiegelmanlab.bsky.social Join us @ #AdiposeBiology Conference in Montreal🇨🇦, Aug 19-20, 2025, to hear from this world leading #metabolism expert! 🔗Register before the early bird deadline at: adiposebiology.com @mcgillgci.bsky.social @danafarber.bsky.social
1127
Reposted by Amanda Smythers
ACLU @aclu.org · 02/04/2025
BREAKING: We're suing the National Institutes of Health over their politically-motivated purge of research grants. This is an unlawful attack on scientific progress that puts lives at risk.
126139972994
Reposted by Amanda Smythers
STAT @statnews.com · 31/03/2025
Nearly 2,000 members of the National Academies called on the Trump administration to halt its “wholesale assault on U.S. science" in an open letter. www.statnews.com/2025/03/31/t...
statnews.com
Nearly 2,000 top researchers call on Trump administration to halt ‘assault’ on science
Nearly 2,000 members of the National Academies called on the Trump administration to halt its “wholesale assault on U.S. science" in an open letter.
923497
Reposted by Amanda Smythers
John Yates @jyates.bsky.social · 26/03/2025
Anybody ever had success by going on the offensive after getting disrespectful and denigrating reviews for a paper? And this was the third round of reviews. I’m guessing the reviewer hasn’t liked that the editor is keeping the paper alive. The other reviewers have signed off.
5111
Reposted by Amanda Smythers
Solis Lab @ FSU @chrissolis.bsky.social · 06/03/2025
I feel so fulfilled for having served as part of the @us-hupo.org Early Career Researcher Committee for the last two years. At #USHUPO2025, we had the opportunity to invite a group of brilliant high school students to show them what proteomics is about #TeamMassSpec
162
Reposted by Amanda Smythers
Mike Feigin 🥯 @mikefeigin.bsky.social · 03/03/2025
Take a good look at who is speaking out. Grad students are running the biggest science protest because no one else would. Institutions are going to be targeted no matter what we do. Might as well go down fighting.
837085
Reposted by Amanda Smythers
Charles Я. Davis @charliearchy.bsky.social · 28/02/2025
No, this is the most ashamed you've felt as an American *so far*.
118119222193
Amanda Smythers @amandalsmythers.bsky.social · 28/02/2025
Ashamed to live in a country where the leaders don’t support basic human rights.
050
Reposted by Amanda Smythers
MAKS 26 👀🇺🇦 @maks23.bsky.social · 28/02/2025
🇫🇷🇺🇦 "Russia is the aggressor, Ukraine is the victim," - Macron on Trump and Zelensky's dispute in the Oval Office
242167383
Amanda Smythers @amandalsmythers.bsky.social · 25/02/2025
One of the coolest parts of yesterday was the Bruker CEO getting up to share some upcoming advancements during the lunch seminar! This is the second conference in a row I’ve seen Frank walking around and taking notes and it is pretty awesome. #USHUPO2025
080
Amanda Smythers @amandalsmythers.bsky.social · 25/02/2025
My favorite takeaway from #USHUPO2025 so far?! Building a business is not too different from building a lab. Huge thanks to @lindsaykpino.com & @nmriley.bsky.social for hosting a phenomenal workshop on the business of starting a lab!!!
0214
Amanda Smythers @amandalsmythers.bsky.social · 24/02/2025
Kicking off #USHUPO2025 parallel sessions with Molecular Metabolism- featuring invited speaker Linda Cox from Wake Forest!
070
Reposted by Amanda Smythers
Jordan Burton @jobburt.bsky.social · 23/02/2025
The Early Career Researcher day is in full swing today at #USHUPO - we are discussing “Managing Uncomfortable Conversations & Relationships in the Workplace”.
The ECR committee
1103
Amanda Smythers @amandalsmythers.bsky.social · 21/02/2025
Very excited to see many friends (and soon to be friends) at @us-hupo.bsky.social this weekend! The ECR committee has SO much programming, including a full mentorship day Sunday (all are welcome- no sign up required!), starting a lab workshop & elevator pitches Monday, & lab pitches Tuesday. 1/
170
Reposted by Amanda Smythers
Daniel Drucker @danieljdrucker.bsky.social · 17/02/2025
A combination of #exercise physiology, molecular biology & biochemistry studies identifies the Ergothioneine-3-mercaptopyruvate sulfurtransferase axis as a molecular mechanism for regulating mitochondrial function and #exercise performance @cp-cellmetabolism.bsky.social www.cell.com/cell-metabol...
cell.com
Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST
Sprenger et al. used a systematic approach to identify how mitochondria remodel their metabolome in response to exercise. The diet-derived, atypical amino acid ergothioneine (EGT) accumulates in muscl...
085
Amanda Smythers @amandalsmythers.bsky.social · 09/02/2025
The sanctimonious BS I’ve seen from some scientists I used to respect (re: funding cuts, etc) is absolutely bonkers. Cheering on the end of academic science in some I-told-you-so manner just makes you an asshole, not an “innovator,” no matter how many fellow blue checks tell you otherwise.
2100
Amanda Smythers @amandalsmythers.bsky.social · 07/02/2025
I’m thrilled to announce I was selected to be a @danafarber.bsky.social Trustee Science Committee Fellow! This generous award provides me 3 years of guaranteed funding for salary & other research expenses. The Trustee Science Committee, consisting of Dana-Farber Board members, is designed to… 1/
8422
Amanda Smythers @amandalsmythers.bsky.social · 03/02/2025
I’m a bit overwhelmed by what’s happening politically in the US, but I want to make a few opinions very clear: 1. Diversity is a wonderful thing and every coworker I’ve ever met from marginalized communities worked their ass off to get there. 2. Attacking Canada and Mexico is fucking stupid. 1/
1110
Reposted by Amanda Smythers
Stacey Ogden 🦔 @labogden.bsky.social · 01/02/2025
The news coming out of Washington is taking a toll on all of us. I don't know who needs to hear this today, but take care of yourselves. Take a break. Go out in nature. Hang with your family/friends/pets. Refill your mental/emotional fuel tanks and rejoin the fight when you're ready. 🧪 ✊
612219
Reposted by Amanda Smythers
Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 31/01/2025
www.forbes.com/sites/roncar...
forbes.com
One More Time: Why Diversity Leads To Better Team Performance
Discussions on diversity in the workplace can be heated and contentious. But the data still shows more diverse teams outperform their less diverse peers. Here's how.
3293107
Amanda Smythers @amandalsmythers.bsky.social · 29/01/2025
Amazing opportunity in a fantastic lab! Come be my neighbor! ⬇️
011
Reposted by Amanda Smythers
Metabo_Dave @metabodave.bsky.social · 26/01/2025
I think we should be cautious about embracing the "NIH needs reform" nonsense. The sort of reform you are all thinking about bears little resemblance to what the right wingers have in mind. Don't be naive.
16725103
Reposted by Amanda Smythers
ProteomicsNews (Ben Orsburn) @proteomicsnews.bsky.social · 23/01/2025
No Proteomics Show podcast tomorrow. Hopefully we'll be able to eventually post a recording with a phenomenal young reseacher who has done tens of thousands of patient proteomes (4 papers already in 2025!) Government representatives told us to cancel the show release.
5173
Amanda Smythers @amandalsmythers.bsky.social · 20/01/2025
I took this photo as the sun rose on Obama’s 1st inauguration. It was a beautiful day full of hope. I waited outside beginning at 4 am to be there, joined by tens of thousands of others. I have a wealth of feelings today, but mostly I feel a lack of hope. What a tough time to be an American.
2100
Amanda Smythers @amandalsmythers.bsky.social · 08/01/2025
I completely agree with this! @harvardcellbio.bsky.social is a wonderfully supportive department filled with outstanding, collaborative researchers. So lucky to be here!
020