Sign in

Naomi McGovern

@mcgovernlab.bsky.social
122 followers 145 following 19 posts

Mononuclear phagocytes in health, disease and pregnancy

PostsRepliesMedia
Reposted by Naomi McGovern
Robin Burns @robinburns.bsky.social · 25/07/2026
Delighted to share our paper on neo-chromosomes! We induced centromere fission using CRISPR in Arabidopsis and increased the chromosome count from n=5 to n=6. The broken chromosomes ends quickly “healed” by adding telomeres de novo and the new karyotype is stable through mitosis and meiosis! 1/3
14320
Reposted by Naomi McGovern
Early-life Immune Network Europe @efis-eline.bsky.social · 26/03/2026
1 week until our next seminar! 🎉 Register here: www.efis-eline.eu/seminars
023
Naomi McGovern @mcgovernlab.bsky.social · 26/03/2026
I’m excited to share our lab’s latest preprint, led by Joe Hutton. We take a deep look at monocytes in psoriatic arthritis (PsA), uncovering a population of circulating cells that are uniquely primed to become osteoclasts—cells responsible for breaking down bone. www.biorxiv.org/content/10.6...
biorxiv.org
011
Naomi McGovern @mcgovernlab.bsky.social · 23/03/2026
Huge congratulations to our colleague, Mahlaqua Noor, for being recognised as one of this year’s 21toWatch winners. An outstanding achievement and so well deserved — we’re incredibly proud to have her on the team: www.cambridgemc.com/21towatch-20...
cambridgemc.com
#21toWatch 2026 Winners Revealed
The #21toWatch Top21.2026 winners have been announced at an awards ceremony at The Glasshouse innovation hub in Cambridge.
000
Reposted by Naomi McGovern
Early-life Immune Network Europe @efis-eline.bsky.social · 18/03/2026
Nearly every baby is colonized by various E. coli at birth, but luckily only 1 in 1000 develops a severe infection: A new paper in Nature shows how maternal IgG specific to mum`s gut E.coli protects neonates. Read here: www.nature.com/articles/s41... #EFIS #ELINE #NeonatalImmmunology (1/7)
nature.com
Natural maternal immunity protects neonates from Escherichia coli sepsis - Nature
Neonatal sepsis caused by Escherichia coli is associated with reduced transfer of pathogen-specific maternal antibodies and, in a mouse model, can be prevented by maternal preconceptual&nbsp...
163
Reposted by Naomi McGovern
Early-life Immune Network Europe @efis-eline.bsky.social · 01/03/2026
New exciting #NeonatalImmunology paper: Peripheral immune-inducer dendritic cells drive early-life allergic inflammation (1/5) www.nature.com/articles/s41...
nature.com
Peripheral immune-inducer dendritic cells drive early-life allergic inflammation - Nature
Early-life exposure to allergens triggers a distinct local mode of dendritic cell activation in neonatal skin without requiring migration to lymph nodes, which shapes responses to allergens in later l...
153
Naomi McGovern @mcgovernlab.bsky.social · 17/02/2026
Passionate about science? Looking for a new exciting role? Then join our team. This post has just opened: www.cam.ac.uk/jobs/researc...
cam.ac.uk
Research Assistant/Associate in Immunology (Fixed Term)
Fixed-term: The post is available for two years in the first instance starting as soon as possible and subject to a 6-month probationary period. Join our team as a Postdoctoral Research Associate in
012
Reposted by Naomi McGovern
Early-life Immune Network Europe @efis-eline.bsky.social · 06/02/2026
We are excited to kick-off of our seminar series on March 5, 4pm CET 🥳 🎤 Petter Brodin – A seeding reaction to colonizing microbes in human newborns 🎤 Eva Stange – Neonatal liver niches program T cell tolerance Register here: www.efis-eline.eu/seminars #EarlyLifeImmunity #Immunology #EFIS
efis-eline.eu
EFIS-ELINE - Seminars
Seminars run on the first Thursday of every month at 16:00 CET. We kick off with a 15-minute spotlight talk from an early-career researcher, then a senior scientist takes the stage for a deeper dive, ...
154
Naomi McGovern @mcgovernlab.bsky.social · 05/02/2026
I would like to share the launch of ELINE – the Early Life Immunity Network Europe. The seminar series takes place on the first Thursday of each month, starting on March 5th @ 16:00 CET Our first speakers are Eva Stange & Petter Brodin Registration: www.efis-eline.eu/seminars
efis-eline.eu
EFIS-ELINE - Seminars
Seminars run on the first Thursday of every month at 16:00 CET. We kick off with a 15-minute spotlight talk from an early-career researcher, then a senior scientist takes the stage for a deeper dive, ...
000
Reposted by Naomi McGovern
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 30/10/2025
Calling all postdocs / early career researchers! The Loke CTR Next Generation Fellowship is a stepping stone to research independence! Visit 🔗 www.trophoblast.cam.ac.uk/next-generat... Need guidance to find a research sponsor? Register your interest via our short form forms.office.com/e/vST36RSB96
031
Reposted by Naomi McGovern
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 02/10/2025
Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇 - Funded PhD www.trophoblast.cam.ac.uk/phd-students... - Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat... - MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
01014
Naomi McGovern @mcgovernlab.bsky.social · 02/10/2025
Applications are open for the Next Generation Fellowship – applications until 30 January 2026 www.trophoblast.cam.ac.uk/next-generat...
trophoblast.cam.ac.uk
Next Generation Fellowship Overview | Loke Centre for Trophoblast Research
Next Generation Fellowships The Loke Centre for Trophoblast Research has an established highly-successful program to fund and mentor Next Generation Research Fellowships.
000
Naomi McGovern @mcgovernlab.bsky.social · 02/10/2025
Applications are open! For anyone looking to pursue a PhD in cutting-edge research in early development, maternal-fetal interaction, or placental biology: www.trophoblast.cam.ac.uk/phd-students...
trophoblast.cam.ac.uk
PhD Studentships | Loke Centre for Trophoblast Research
The Loke Centre for Trophoblast Research (Loke CTR) offers fully-funded 4-year PhD studentships for home or overseas students The Loke Centre for Trophoblast Research (Loke CTR) provides a dynamic env...
001
Naomi McGovern @mcgovernlab.bsky.social · 23/09/2025
An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...
nature.com
The mini placentas and ovaries revealing the basics of women’s health
Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.
013
Reposted by Naomi McGovern
Elaine Emmerson @doctoremmerson.bsky.social · 22/09/2025
Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.
093
Reposted by Naomi McGovern
The French DC Society - Club Francophone des DC (CFCD) @frenchdcsociety.bsky.social · 09/09/2025
🚨 New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-α stimulation. Fascinating plasticity! 👇 www.nature.com/articles/s41...
nature.com
TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells - Nature Immunology
Plasmacytoid dendritic cells are type 1 interferon (IFN-I)-producing antiviral specialists that have been shown to be able to differentiate into conventional dendritic cells. Here the authors show how...
041
Reposted by Naomi McGovern
Matthew Freeman @mjafreeman.bsky.social · 01/09/2025
Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on! www.path.ox.ac.uk/work-with-us...
path.ox.ac.uk
Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
06767
Naomi McGovern @mcgovernlab.bsky.social · 21/07/2025
This is a second video shows Listeria monocytogenes (green) recruiting host cell actin (red) in term Hofbauer cells. Created by Nagisa Yoshida
020
Naomi McGovern @mcgovernlab.bsky.social · 21/07/2025
Here is a video from our manuscript capturing Hofbauer cells interacting with each other in placental villi explants
010
Naomi McGovern @mcgovernlab.bsky.social · 21/07/2025
Happy share this latest study from the team. Here we look at placental macrophage biology across pregnany and their interaction with Listeria monocytogenes. www.science.org/doi/10.1126/...
science.org
Interactions between placental Hofbauer cells and L. monocytogenes change throughout gestation
Gestational changes in Hofbauer cells alter their interactions with Listeria monocytogenes.
3159
Reposted by Naomi McGovern
Elaine Emmerson @doctoremmerson.bsky.social · 26/05/2025
Congratulations to @drbmalengier.bsky.social, @magmarlene.bsky.social and Team Gentek of @edinuni-irr.bsky.social for this amazing tour de force, comprehensively characterising #synovial #macrophage #development 💪🏻
0113
Reposted by Naomi McGovern
Science Magazine @science.org · 06/05/2025
NIH’s new director Jay Bhattacharya discusses staff morale, grant cuts, and “rumors” in an interview with Science. scim.ag/4mhSMpA
scim.ag
‘It’s been a tough period’: NIH’s new director speaks with Science
Jay Bhattacharya discusses staff morale, grant cuts, and “rumors”
5357
Reposted by Naomi McGovern
Naomi McGovern @mcgovernlab.bsky.social · 25/04/2025
Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken. Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
021
Reposted by Naomi McGovern
Kiwook @kim-lab.bsky.social · 29/04/2025
Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! 🎉 It’s been a long journey, and I’m incredibly grateful to all my co-authors—especially Dr. Teruyuki_Sano—for your dedication. This wouldn’t have been possible without you! www.cell.com/immunity/ful...
cell.com
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis
Immune-microbiota interactions are required to maintain host homeostasis. Kim et al. identified that steady-state sensing of IL-10 by interstitial macrophages (IMs) prevents spontaneous lung inflammat...
1469
Naomi McGovern @mcgovernlab.bsky.social · 25/04/2025
Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken. Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
021
Reposted by Naomi McGovern
Science Magazine @science.org · 16/04/2025
A new Science study reveals genetic links between pelvic structure and function, locomotion, and childbirth outcomes. The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb
scim.ag
The genetic architecture of and evolutionary constraints on the human pelvic form
Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical ...
1577
Reposted by Naomi McGovern
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 19/03/2025
🔬 Does your research explore placental ageing, senescence, prolonged pregnancy, or term complications like pre-eclampsia? Join leading experts at our Annual Meeting! Registration open, don’t miss your chance to be part of the discussion. www.trophoblast.cam.ac.uk/ctrconferenc...
134
Reposted by Naomi McGovern
Nature Portfolio @natureportfolio.nature.com · 04/04/2025
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. 🧪
go.nature.com
How Trump is following Project 2025’s radical roadmap to defund science
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page blueprint. Nature read it so you don’t have to.
16030
Reposted by Naomi McGovern
emds2025.bsky.social @emds2025.bsky.social · 04/04/2025
Great to see the abstracts start to come in for EMDS2025. We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.
045
Reposted by Naomi McGovern
Rebecca Fielding-Miller @rebeccafieldingmiller.com · 22/03/2025
Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women. More women are murdered in the perinatal period than die of obstetric complications. I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
850288139020
Reposted by Naomi McGovern
Prof Sheena Cruickshank @sheencr.bsky.social · 21/02/2025
New research shows that treatment of a rare and often fatal neurodegenerative condition in utero has been a success with the child still symptom free at 2 and a half years. 🧪
nature.com
Rare genetic disorder treated in womb for the first time
The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.
0639
Reposted by Naomi McGovern
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 12/02/2025
The Loke CTR team have worked hard on laboratory sustainability and efficiency and have been awarded LEAF Bronze status as a result! More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...
183
Reposted by Naomi McGovern
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 10/02/2025
We welcomed @margaridamcm.bsky.social to Cambridge last week. Margarida presented her talk 'The evolution of new cell types and organs: the view from the placenta'. We are very grateful to her for spending the day with us, meeting colleagues and presenting her fascinating research.
042
Reposted by Naomi McGovern
Nature Portfolio @natureportfolio.nature.com · 02/02/2025
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. Nature reports on the search to find out what they do. 🧪
go.nature.com
‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.
07225
Reposted by Naomi McGovern
Charlotte Scott @charlottelscott.bsky.social · 24/01/2025
With my first Bluesky post, I am very happy to share our latest study led by PhD student Federico De Ponti and postdoc Ania Bujko www.cell.com/immunity/ful...
cell.com
Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair
scRNA-seq has uncovered ontogenically distinct hepatic macrophage populations, but their functions remain unclear. Here, De Ponti et al. identify recruited LAMs and resident LAM-like KCs in multiple l...
45316
Reposted by Naomi McGovern
The Loke Centre for Trophoblast Research @loke-ctr.bsky.social · 08/01/2025
For anyone following here who's not seen this on our other channels, closing date for the Loke CTR Next Generation Fellowship is 31 Jan 2025, details here www.trophoblast.cam.ac.uk/next-generat... Feel free to share in your networks!
trophoblast.cam.ac.uk
Next Generation Fellowship Overview | Loke Centre for Trophoblast Research
Next Generation Fellowships Applications now open ngf_application_timeline-02.png The Loke Centre for Trophoblast Research has an established highly-successful program to fund and mentor Next Generat...
024
Naomi McGovern @mcgovernlab.bsky.social · 07/01/2025
Congrats to Ashley on this prestigious award www.path.cam.ac.uk/news/profess...
path.cam.ac.uk
Professor Ashley Moffett awarded Companion of the Order of St Michael and St George | Department of Pathology
We are delighted to announce that Professor Ashley Moffett has been awarded Companion of the Order of St Michael and St George in the King's New Year's Honours.
000
Reposted by Naomi McGovern
Calum Bain @bainlab.bsky.social · 17/12/2024
‼️ SAVE THE DATE The next EMDS Meeting will take place from 16-18th Sept. 2025 in majestic Edinburgh 🏴󠁧󠁢󠁳󠁣󠁴󠁿. If you love macs, monos &/or DCs, or just want to learn more about them, THIS is the meeting for you. Space limited - so watch out for details. @britsocimm.bsky.social
02711
Naomi McGovern @mcgovernlab.bsky.social · 05/12/2024
Beautiful review from Courtney Hanna @cwhanna.bsky.social and team. Now Online: Origin, fate and function of extraembryonic tissues during mammalian development go.nature.com/3OELOeK
go.nature.com
Origin, fate and function of extraembryonic tissues during mammalian development - Nature Reviews Molecular Cell Biology
During mammalian embryogenesis, extraembryonic tissues are required for the patterning and morphogenesis of the embryo. This Review discusses how signalling networks and epigenetic modifications regul...
030
Reposted by Naomi McGovern
Calum Bain @bainlab.bsky.social · 29/11/2024
#EMDS2024 was brilliant. Thx to all the organisers. Planning is well underway for EMDS25: Scotland Edition. We look forward to welcoming you to beautiful Edinburgh next year. 👀 for details in the coming months. @britsocimm.bsky.social @cytokinesociety.bsky.social @societymucosalimm.bsky.social
0289