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Therapeutic resistance remains a barrier to durable treatment of colorectal cancer (CRC), highlighting the need to identify vulnerabilities in resistant tumor cells. REV7 (MAD2L2) is a multifunctional...

Everybody knows the old saying that “absolute power corrupts absolutely.” It’s a maxim as old as time, and the lesson of any number of works of fiction — and history

The Blues ended two successive defeats to get their season up and running

Pete Herzog runs the popular NFL account 'Film Watchers.' Even some Saints players even watch his channel for insight into their opponents.

Yang et al. show that α-satellite RNA, derived from human centromeric satellite repeats, forms R-loops at human centromeres to ensure faithful chromosome segregation by recruiting Shugoshin 1. This me...

SUMO ligases conjugate the SUMO modifier to target proteins, thus regulating their functions. Here, the authors reveal how DNA and ATP binding by the multiple subunits of the SUMO ligase complex Smc5/6 enable its efficient SUMOylation of genome maintenance proteins.

Social media transformed his campaign into a political mirage.

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