Mattias Malaguti @matt-mala.bsky.social · 02/09/2026Our lab's claim to fame: DNessie was featured by @plasmidsaurus.bsky.social Artwork by the multi-talented Eva Gonzalez Suarez and Mash Bandouil! 110
Reposted by Mattias MalagutiAlex Eve @amjeve.uk · 18/06/2026Journal impact factors were released yesterday. In our latest @dev-journal.bsky.social Editorial, @jamesbriscoe.bsky.social and I discuss how we are all architects of impact, highlighting that measuring the influence and support journals provide goes beyond a single number. doi.org/10.1242/dev....doi.orgThe elephant in the room: impact factorSummary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ... 04420
Reposted by Mattias MalagutiMichalis Averof @michalis-averof.bsky.social · 19/04/2026Finding molecular tags that localise fluorescent proteins to the cell membrane was the goal of our latest paper, now published in Development @dev-journal.bsky.social. The tags act as address labels, sending proteins to the cell membrane, where they highlight the shape and arrangement of cells. 2/9journals.biologists.comTargeting the cell membrane in established and emerging model organismsSummary: Screening a toolkit of diverse membrane-localising tags identifies candidates that efficiently localise proteins to the plasma membrane in a wide range of animals and choanoflagellates. 25519
Reposted by Mattias MalagutiNaomi Moris @nmoris.bsky.social · 20/04/2026I am giving a "Crash Course in Embryo Development" for the general public (no science background needed! pitched around GCSE-level) in London on 21st May www.crick.ac.uk/whats-on/cri... We'll dip into development, with a splash of embryo models, and a pinch of ethics. And it's free! Book online 👍crick.ac.ukCrick Crash Course: Embryo development 07025
Reposted by Mattias MalagutiSally Lowell @cellysally.bsky.social · 31/03/2026The ABC of my fave things in this paper: * ABOLISHING both silencing AND leakiness of SynNotch (check out the DTA-based demo of this 😍) while preserving high efficiency, in pluripotent & differentiating cells * BOOSTING signal during #PUFFFIN neighbour-labelling * CITING Robbie Burns (1786) 🏴 051
Mattias Malaguti @matt-mala.bsky.social · 24/03/2026This work was carried out by the incredible @edinuni-irr.bsky.social PhD student Aisling Fairweather, and the brilliant @edinburghbiology.bsky.social undergraduate Yana Slavova, who joined the lab on a @biologists.bsky.social Gurdon Summer Studentship. 010
Mattias Malaguti @matt-mala.bsky.social · 24/03/2026Delighted to introduce KELPE: mESCs with two insulated genomic landing pads, which we use to generate new synNotch and PUFFFIN neighbour-labelling lines. They were named after kelpies, creatures from Scottish folklore, and they look pretty on a kelpie micropattern! #DevBio #SynBio 1157
Reposted by Mattias MalagutiChris Ponting @cgatist.bsky.social · 13/05/2025Want to tell us about your challenges in interdisciplinary research within bioinformatics & biomedicine? Please take our HxC survey! Our aim is to create lasting change and address barriers to interdisciplinary collaboration and creativity app.onlinesurveys.jisc.ac.uk/s/edinburgh/... Thank youapp.onlinesurveys.jisc.ac.ukHxC Survey on Interdisciplinary Work 044
Mattias Malaguti @matt-mala.bsky.social · 09/04/2025@ely-pavezlorie.bsky.social thank you! We're taking a bottom-up approach. We'll be using human epidermal equivalents to start with, and we'll add in more complexity (e.g. full thickness equivalents) as we progress. 100
Mattias Malaguti @matt-mala.bsky.social · 09/04/2025Extremely thankful to @acmedsci.bsky.social for the opportunity, and very excited to get started on this project at @edinburgh-uni.bsky.social ! #Springboard25 2151
Reposted by Mattias MalagutiAcademy of Medical Sciences @acmedsci.bsky.social · 08/04/2025🚨 Just 2 weeks left to apply for our Policy Internship with the Medical Research Council. Gain hands-on experience in science policy, insight into research impact and connect with top UK health leaders 🌟 Open to 3rd and 4th year MRC funded PhD students. 👉 Learn more and apply: lnkd.in/eNrYvPMh 021
Reposted by Mattias MalagutiThe Company of Biologists @biologists.bsky.social · 08/04/2025We are highlighting Kate Storey, who served as a Director at @biologists.bsky.social from 2007 to 2022 and co-founded the Company’s Workshop programme, as an extraordinary biologist. #100biologists 1185
Reposted by Mattias MalagutiAida Rodrigo @aidarodrigo.bsky.social · 28/03/2025Interested in biological research beyond the standard? Join us in Edinburgh for the EMBO Workshop exploring how unconventional vertebrate models are becoming engines for biomedical research! 🦇 🐿️ 🦌 🐒 🦍 🐹🧍♀️ 🚨 Abstract submission deadline: 11 April 2025 🚨 meetings.embo.org/event/25-ver...meetings.embo.orgBeyond the standard: Unconventional vertebrate models in biomedicineThe use of a handful of model organisms has proven essential for scientific discovery and to unlock new therapeutics to combat human disease. As society looks to the future, the gateway to new scient… 11511
Reposted by Mattias MalagutiDevelopment @dev-journal.bsky.social · 08/04/2025In this Review, @bernasozen.bsky.social, Patrick Tam & Martin Pera summarize how recent studies of embryo models have advanced our understanding of cell state transitions of the pluripotent human epiblast and highlights some key remaining questions: doi.org/10.1242/dev.... 0133
Reposted by Mattias MalagutiTakuya Azami @tazami.bsky.social · 07/04/2025Happy to share our study on Stat3, now published in Cell Reports! Huge thanks to all collaborators! www.cell.com/cell-reports...cell.comSTAT3 signaling enhances tissue expansion during postimplantation mouse developmentAzami et al. reveal that STAT3 deletion depletes epiblast cells at implantation, causing a persistent developmental delay of around a day. STAT3 null embryonic stem cells contribute to all embryonic t... 021
Reposted by Mattias MalagutiDevelopmental Biology @devbiol.bsky.social · 04/04/2025Social Media Volunteers Needed! Developmental Biology is building a social media team (Bluesky X LinkedIn Insta )😎 If you're a passionate developmental biologist & interested in working with other social media enthusiasts for DB, apply today!😆 Deadline Apr 30 docs.google.com/document/d/1... 02423
Reposted by Mattias MalagutiStem Cell Summer School @stemcellsummer.bsky.social · 07/04/2025The 2025 European Summer School in Stem Cell Biology and Regenerative Medicine will take place 12-19 Sept 2025, on the beautiful Greek island of Spetses. Keep an eye on our website www.stemcellsummerschool.org for updates, or give us a follow 😀 Deadline for applications: 30th May 2025 01510
Reposted by Mattias Malagutithe Node @the-node.bsky.social · 07/04/2025March in preprints In this latest monthly preprint list, we look back at the #DevBio and #StemCells #preprints that came out in March. (Let us know if we've missed anything!) thenode.biologists.com/march-in-pre...thenode.biologists.comMarch in preprints - the NodeWelcome to our monthly trawl for developmental and stem cell biology (and related) preprints. The preprints this month are hosted on bioRxiv and arXiv – 0165
Mattias Malaguti @matt-mala.bsky.social · 07/04/2025I'm over the moon for receiving an @acmedsci.bsky.social #Springboard25 award! We will use these funds to apply our synthetic neighbour-labelling tools to human skin organoids, to study communication between diseased cells and healthy neighbours. #EngBio #SynBio #DevBio #SkinResearch #CancerResearch 290
Reposted by Mattias MalagutiGuillaume Jacquemet @guijacquemet.bsky.social · 07/04/2025Here we share our opinions on "Practical considerations for data exploration in quantitative cell biology" journals.biologists.com/jcs/article/... Joanna, Hanna and I worked quite a bit on this piece and I hope you find it useful Many thanks to @jcellsci.bsky.social for publishing itjournals.biologists.comPractical considerations for data exploration in quantitative cell biologySummary: We present practical guidelines for data exploration in quantitative cell biology that are designed to help yield reliable conclusions and promote a collaborative, transparent approach to dat... 47636
Mattias Malaguti @matt-mala.bsky.social · 03/04/2025Hello! My lab is interested in understanding how healthy mammalian cells sense and react to mutant neighbours. We do this by developing and using engineering biology tools to identify and manipulate neighbours of mutant cells. We also love taking colourful microscopy pictures! 1124