Reposted by Masha Prager-KhoutorskyCANGlia @canglia.bsky.social · 15/05/2026Dr. Prager-Khoutorsky sharing some exciting tanycyte data! #tanycytes 171
Reposted by Masha Prager-KhoutorskyBiomedical Picture of the Day BPoD @bpodaily.bsky.social · 20/09/2025Targeting the brain's vasopressin neurons could be a novel treatment for high blood pressure 📹 Ning Gu et al @mashapk.bsky.social lab @mcgilluniversity.bsky.social in @cp-neuron.bsky.social ➡️ bpod.org.uk/archive/2025... with @rooph.bsky.social 122
Masha Prager-Khoutorsky @mashapk.bsky.social · 19/08/2025Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉 23213
Reposted by Masha Prager-KhoutorskyBaptiste Lacoste @blacoste.bsky.social · 04/07/2025Microglial control of cerebral capillary basal tone. Congrats to @eyolab.bsky.social & team ! #cerebrovascularnature.comMicroglial cyclooxygenase-1 modulates cerebral capillary basal tone in vivo in mice - Nature CommunicationsThe role of myeloid cells in vascular regulation remains incompletely understood. Here, the authors show that microglia are the only myeloid cells that localize to capillaries and that they maintain b... 0146
Reposted by Masha Prager-KhoutorskyBaptiste Lacoste @blacoste.bsky.social · 04/07/2025#Pericytes #cerebrovasculardoi.orgPericyte pannexin1 controls cerebral capillary diameter and supports memory function - Nature CommunicationsBrain contractile pericytes control capillary blood flow to match neuronal demands. Here, the authors show that pericytes express ATP-releasing pannexin1 channels and establish their role in the regul... 0113
Reposted by Masha Prager-KhoutorskyJesper Sjöström @pjsjostrom.bsky.social · 14/04/2025🧪 The Sjöström Lab in Montreal is looking for a postdoc! We study cortical circuits, synaptic plasticity, and NMDAR signalling using custom 2-photon microscopy and optogenetics. We seek candidates with strong patch-clamp and/or 2-photon imaging expertise, and a relevant publication track record. 22725
Reposted by Masha Prager-KhoutorskyJesse Shapiro @bjesseshapiro.bsky.social · 24/04/2025Come join us at @mcgill.ca as an assistant professor in virus-host interactions! Please share widely. mcgill.wd3.myworkdayjobs.com/en-US/McGill...mcgill.wd3.myworkdayjobs.comAssistant Professor (Research), Department of Microbiology & Immunology, (C2-240724)Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ... 16391
Masha Prager-Khoutorsky @mashapk.bsky.social · 24/04/2025An iconic example of a successful combination of basic and clinical/translational research, offering real promise for treating a currently incurable disease #Fibromyalgia -congrats to all the authors🥂🍾👏🏽 010
Reposted by Masha Prager-KhoutorskyJonathan Kipnis @jonykipnis.bsky.social · 21/03/2025Excited to share our work by exceptional postdoc, Kyungdeok (KD) Kim. 2025 marks 10th anniversary of meningeal lymphatic discovery and I can’t be happier celebrating it with this work addressing how lymphatic dysfunction leads to cognitive deficits || www.sciencedirect.com/science/arti...sciencedirect.comMeningeal lymphatics-microglia axis regulates synaptic physiologyMeningeal lymphatics serve as an outlet for cerebrospinal fluid, and their dysfunction is associated with various neurodegenerative conditions. Previo… 2264
Reposted by Masha Prager-KhoutorskyMathieu Ferron @mathieuferron.bsky.social · 18/03/2025Tenure track position in pharmacology or toxicology at McGill, in Montreal!!! www.nature.com/naturecareer...nature.comAssistant / Associate Professor (Tenure Track), Department of Pharmacology and Therapeutics - Montréal, Quebec (CA) job with McGill University | 12837963Faculty of Medicine and Health Sciences – Department of Pharmacology and Therapeutics, Toxicology (L000054 15747
Reposted by Masha Prager-KhoutorskyCaroline Menard @caromenard666.bsky.social · 27/02/2025So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳 Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI www.nature.com/articles/s41...nature.comAstrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature NeuroscienceThe mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri... 2011535
Reposted by Masha Prager-KhoutorskyCatherine Dulac @dulaclab.bsky.social · 26/02/2025Our latest findings on social behavior circuits is out: how does the brain responds to social isolation? Terrific work by @dingliu.bsky.social et al. uncovering a circuit with similar neural architecture as physiological needs (hunger, thirst, sleep..). Detailed thread soon. rdcu.be/ebo63rdcu.beA hypothalamic circuit underlying the dynamic control of social homeostasisNature - New data on brain-wide circuits centred around two interconnected hypothalamic neuron populations provide significant mechanistic insights into the emergence of social need during social... 517064
Masha Prager-Khoutorsky @mashapk.bsky.social · 24/02/2025In our new preprint, we show that microglia can prune astrocyte processes to regulate synaptic transmission and hypothalamic neuron activity. This work represents a huge team effort spanning ~10 years, and we are very excited to finally share it with the world! 3369
Reposted by Masha Prager-KhoutorskyPaul Frankland @franklandlab.bsky.social · 27/12/2024Just bumping this up for those who may have missed earlier announcements-- we have a new PI position in the Neuroscience & Mental Health program here at SickKids. Neural and glial mechanisms in cognition.can-acn.orgScientist/Senior Scientist – Research Institute, Hospital for Sick Children, University of Toronto – Canadian Association for Neuroscience 07166
Masha Prager-Khoutorsky @mashapk.bsky.social · 26/12/2024Working on manuscript revisions during holidays🎄🎅🕎🍩🕯️ in 🇲🇽 with🍹🍸!!! 060
Masha Prager-Khoutorsky @mashapk.bsky.social · 20/12/2024Huge congrats to Dr. Amirah Hicks on successfully defending her PhD! 🎉🥂👏 Amirah is my first trainee to earn a doctoral degree, and I couldn't be more proud of her accomplishments. I'm incredibly excited for the new chapter that lies ahead for her! 1111