New research from the Wood Neuro Research Group suggests sickle cell disease changes how the brain’s networks work together, with the brain calling on extra support from attention systems to keep thin...

Hesitation—pausing in the face of uncertainty—is ubiquitous in daily life and disrupted in several psychiatric disorders. Unlike other forms of response inhibition, hesitation is mediated by indirect,...

Hodge et al. used closed-loop optogenetic stimulation and naturalistic behaviors to determine that striatal activity does not select the action to perform but rather biases performance through reinfor...

Our body executes many different movements with precision. Falasconi and Arber describe how basal ganglia interact with brainstem circuits controlling body movements and propose a movement-specific li...

In natural environments, animals must efficiently allocate their choices across multiple concurrently available resources when foraging, a complex decision-making process not fully captured by existin...

Curiosity and exploration support learning and adaptive decision-making in uncertain environments. While these processes are sensitive to motivational context, it remains unclear how outcome valence s...

Automated quality control, curation and neuron classification of spike-sorted electrophysiology data - Julie-Fabre/bombcell

Basal ganglia output neurons fire dynamically in bidirectional and movement-specific patterns to license forelimb movements. 

Timothy Verstynen has always been fascinated by how organisms explore their environments — from the human quest to map the surfaces of distant planets to the itty-bitty journeys of single-celled bacte...

Corbit et al. studied patterns of activity in corticostriatal circuits during naturally occurring complex behavior in mice. In contrast to models in which cortex leads striatum, these findings suggest...