iiinova — where your digital self keeps evolving

Reposted by Maik Bischoff

Stefan Luschnig @luschnig.bsky.social · 7h

New paper by Harshath Amal @harshath.bsky.social shows how TGF-β signaling controls epithelial permeability by regulating actomyosin contractility and adhesion. Surprisingly, elevated adhesion can maintain barrier integrity independently of contractility tinyurl.com/ywenrexy @jcellsci.bsky.social

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Katja Rust @rustflylab.bsky.social · 10/08/2026

Our contribution to #MicroscopyMonday: While studying #Drosophila tissues, Hannah found a cricket! Isn't is cute???

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Katja Rust @rustflylab.bsky.social · 12/10/2026

Greetings from our regional #Drosophila meeting on #Helgoland! Also amazing meeting @maikbischoff.bsky.social here!

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Reposted by Maik Bischoff

David M. Versluis @davidversluis.bsky.social · 07/10/2026

I have a new paper out: Communication through autoattractants can enhance and limit collective migration of immune cells journals.plos.org/ploscompbiol... We show how complex interactions emerge around a secreted attractant, and you can play with the model online: chemotaxis.org/autoattracta...

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 28/09/2026

Today's winning Biology All email--in fact this is a contender for best this year

Hi all,

We received a package with no name to GSB 2144 with 80 sheep brains in it. If you are expecting this package, please reach out and we can coordinate the pickup!

Best wishes,
Jenna

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 29/09/2026

For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu

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Claire Dessalles @clairedessalles.bsky.social · 23/09/2026

NeMo is finally out! 🐟 We present our new method to peel cellular layers and extract their nematics. If you're wondering what a fish has to do with curved nematics, check out the thread and the publication 👀👇🏼 arxiv.org/html/2609.12...

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c0nc0rdance @c0nc0rdance.bsky.social · 18/09/2026

Brilliant mathematician Emmy Noether was initially barred from teaching at University of Göttingen because she was a woman. She taught for 4 years as a "guest lecturer" under David Hilbert's name. Hilbert, exasperated at the stupidity of the rule: "Gentlemen, this is not a bathing establishment."

artsci.tamu.edu

From Algebra to Airplane Crashes, Emmy Noether’s Lasting Influence on Mathematics

Emmy Noether, whom some consider the “Mother of Modern Mathematics,” continues to shape modern research and the studies of mathematicians today; including research into the investigation of airplane c...

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Maik Bischoff @maikbischoff.bsky.social · 22/09/2026

Thank you and good luck with that! 🍀

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Max Farnworth @maxfarnworth.bsky.social · 23/07/2026

🚨 I am very happy (and relieved!) to announce that I secured Emmy Noether funding by the @dfg.de to start my own group at @unimainz.bsky.social , hosted by Marion Silies & Jakob von Engelhardt in August! 🚨 Website coming soon - open for name/logo suggestions. They better be funny tho!

static.klipy.com

Sophia Petrillo with Megaphone in Golden Girls

ALT: Sophia Petrillo with Megaphone in Golden Girls

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SFB 1348 @sfb1348.bsky.social · 21/09/2026

Many congratulations to @maikbischoff.bsky.social on receiving a @dfg.de Emmy Noether grant! We’re delighted and proud to host you at @sfb1348.bsky.social @uni-muenster.de. We look forward to exciting times and groundbreaking science ahead! 🎉🔬 www.bischofflab.com

bischofflab.com

Bischoff Lab | Morphogenesis | Cell Bio | Chirality | Multiscale Imaging Centre Münster, Germany

We work on cell biology, morphogenesis and organ chirality using Drosophila as a model organism.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

23/23 So, let’s see where this journey takes us! I’ll keep y‘all updated. 😊 For job postings in the future, check my website: www.bischofflab.com/jobs

A heart made of microscopic pictures of the fly testis.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

22/23 I also want to thank Christian Klämbt, Carsten Grasshof and @rwedlichsoldner.bsky.social , and especially @luschnig.bsky.social , for all their support during the grant application. And thank you to Stefan and his entire group for all the help and support as I set up my new lab!

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

21/23 A huge thank you to @jenevievenorton.bsky.social and @saraheclark.bsky.social for all their support throughout the project! Also everyone else from @unc-bcbp.bsky.social who helped with the project! Go Heels!

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

20/23 Of course, I couldn’t have done this without the help of many people. I want to thank @peiferlabunc.bsky.social for giving me the opportunity to pursue my postdoc in his lab. It was there that I was able to lay most of the foundation for this project.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

19/23 We also have our first Bachelor’s student, @larasievers.bsky.social , who has already defended her thesis, and a Master’s student, Dora, who is working on organ asymmetry. It is amazing to see the group slowly taking shape (Groupogenesis). 🥰

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

18/23 Currently, our small group is growing! We have already filled two PhD positions. @juliettea.bsky.social started in the spring, and in November, Andrea will join us for her PhD. www.bischofflab.com/team

From left to right: Dora, Maik, Juliette, Lara

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

17/23 We will use the Drosophila testis to address these question across multiple levels of emergence — from molecular chirality, to cellular behavior, over organ asymmetry all the way up to the evolution of organ shape.

Microscopic pictures of testes of different fly species

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

16/23 Finally, we know that organ asymmetry is linked to the cytoskeleton in multiple ways. But how exactly does cytoskeletal chirality translate into asymmetric organ shape?

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

15/23 Last year, I wrote a perspective article that, in many ways, acts as a mission statement for my lab! If you’re interested in the ideas behind the lab, you can find it here: rupress.org/jcb/article/...

rupress.org

Patterning in motion: Cell interfaces guide mesenchymal collective migration and morphogenesis

Bischoff and Mayor present a framework for comparing mesenchymal collective migration modes and explain their roles in patterning and morphogenesis.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

14/23 In the Drosophila testis, a population of mesenchymal cells is responsible for sculpting the organ into its characteristic (and asymetric) shape. See my postdoc paper: www.science.org/doi/10.1126/... We want to understand how these cells perform this fascinating task on all levels!

science.org

Plexin/Semaphorin antagonism orchestrates collective cell migration and organ sculpting by regulating epithelial-mesenchymal balance

An axon guidance factor restricts gap growth in a non-neuronal migrating cell sheet, allowing organ sculpting.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

13/23 (some papers in which the mesenchyme was shown to take part in morphogenesis) www.cell.com/cell/fulltex... pubmed.ncbi.nlm.nih.gov/38569553/ pubmed.ncbi.nlm.nih.gov/25437543/

cell.com

Patterning and folding of intestinal villi by active mesenchymal dewetting

Subepithelial mesenchyme behaves like a dewetting fluid to pattern and fold the intestinal epithelium, initiating the formation of villi.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

12/23 In many organs, mesenchymal cells, for example, smooth muscle precursors, play an important role in sculpting the developing organ. However, we know much less about how mesenchymal cells and their motility contribute to morphogenesis compared to epithelial cells.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

11/23 This project will look at organ asymmetry! Many of our organs are asymmetric, like the heart, lungs, or intestines. Further, many organs are tubular and must bend, loop, or coil during development to achieve their final shape. We will use the Drosophila testis to understand how this happens.

Cartoon: intestinal malrotation https://malrotationresearch.org/what-is-intestinal-malrotation/

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

10/23 I am deeply honored and humbled to be connected to this legacy through the Emmy Noether Programme. This programme represents something very special, especially in these days: The opportunity to gain scientific independence and pursue scientific questions freely.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

9/23 For example, the fact that the laws of physics don't change over time is connected to the conservation of energy.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

8/23 She showed that whenever the laws of physics have a certain continuous symmetry (meaning that they remain unchanged when you make a continuous change to the system) something corresponding to that symmetry is conserved.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

7/23 Her most famous scientific contribution is Noether's theorem. In 1918, she showed that there is a deep connection between symmetries and conservation laws in physics.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

6/23 She emigrated to the US, where she became a professor at Bryn Mawr College, a women's college in Pennsylvania. This was the first time in her career that she received a regular salary! Sadly, her life was cut short. She died in 1935, aged just 53, following complications after surgery.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

5/23 Still, Emmy Noether never held a regular salaried academic position in Germany and lived for many years on a small inheritance. During the dark years of the Nazi regime, Emmy Noether, who was Jewish, was forced to leave Germany.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

4/23 Emmy Noether (1882–1935) was a German mathematician who fundamentally changed modern mathematics. At a time when women faced enormous barriers in academia, she built a remarkable career in Erlangen, Göttingen and Bryn Mawr, Pennsylvania. She was among the first women in Germany to habilitate.

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

3/23 The funding lasts for six years and is designed to provide an alternative route to the traditional German Habilitation and qualify researchers for a university professorship. In my case, the award comes with around €1.95 million in funding, which of course in wonderful!

bischofflab.com

Team | Bischoff lab

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

2/23 The Emmy Noether-Program(me) is a funding program of the German Research Foundation (@DFG) that gives early-career scientists the opportunity to establish and lead their own independent research group. www.dfg.de/en/research-...

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Maik Bischoff @maikbischoff.bsky.social · 21/09/2026

1/23 I have fantastic news! I am truly honored to have been awarded an Emmy Noether-Grant by @dfg.de @uni-muenster.de Since most of you are not from Germany, I will use the following posts to explain what this Program is, who Emmy Noether was and what my group in Münster will be doing. #cellbio

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Universität Münster @uni-muenster.de · 21/09/2026

3,1 Mio. Euro für exzellente Nachwuchsforschung! 💸 Die @dfg.de nimmt @maikbischoff.bsky.social (Organentwicklung) & Marcel Rey (Nanopartikel) in das Emmy Noether-Programm auf. Wir gratulieren den beiden Forschern zum Aufbau ihrer eigenen Gruppen! 🚀 Mehr Infos: www.uni-muenster.de/news/view.ph...

uni-muenster.de

Neue Emmy-Noether-Gruppen erforschen Organentwicklung und steuerbare Nanopartikel

Die Deutsche Forschungsgemeinschaft fördert den Biologen Dr. Maik Bischoff und den Chemiker Prof. Dr. Marcel Rey in den kommenden sechs Jahren mit insgesamt gut 3,1 Millionen Euro.

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Reposted by Maik Bischoff

Alex Ludwig @alexludwig.bsky.social · 14/09/2026

How do epithelial cells make a lumen as they polarize? We have some exciting new answers to this long standing question. Check out our new paper in which we show that lumen initiation is driven by large vacuoles that deliver a pre-assembled apical cortex to the AMIS: www.nature.com/articles/s41...

nature.com

Bulk delivery of a preassembled apical surface initiates epithelial lumen formation - Nature Communications

Epithelial lumen formation is fundamental to organ development, yet how apical surfaces first emerge remains unclear. Ghosh, Martin, and Chen et al., show that lumen initiation is driven via bulk deli...

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Barriga Lab @eliasbarrigalab.bsky.social · 12/09/2026

Cngratulations to @JoanaESaraiva and Sandra from the lab on their new review @embojournal.org we discussed few points about the coordination of cell state transitions in #embryos and #regeneration Also welcome @joanaesaraiva.bsky.social to BlueSky! link.springer.com/article/10.1...

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The EMBO Journal @embojournal.org · 07/09/2026

Dynamic control of cell state transitions during tissue morphogenesis Elias Barriga et al @eliasbarrigalab.bsky.social review how gene expression, chromatin modifications & microenvironmental biophysical factors contribute to robust coordination of morphogenesis link.springer.com/article/10.1...

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