Sign in

Lorenzo Pasquali

@lorenzpasquali.bsky.social
299 followers 369 following 2 posts

Research professor @UPFBarcelona genetics and regulatory genomics, islet and chromatin but also father, travelling, campervan, sailing, handbike and kayaking.

PostsRepliesMedia
Reposted by Lorenzo Pasquali
Santiago Rodríguez Seguí @rseguilab.bsky.social · 20/06/2026
That's a wrap on #EISG2026 in Barcelona! Three incredible days of islet science, from genomics to clinical translation. Grateful for the talks, discussions, and community that make this meeting so special. Thanks to @lorenzpasquali.bsky.social and @txellrovira.bsky.social for putting this together!
011
Lorenzo Pasquali @lorenzpasquali.bsky.social · 23/05/2026
Last chance to join us in Barcelona! Registration is closing fast for the #EISG2026 meeting (June 17–19). From pioneering islet biology to the latest in diabetes research, our stellar scientific program is packed. Secure your spot now! 🧬👇 tacticsmd.net/congreso/isl...
tacticsmd.net
Programme - Islet Study Group Conference 2026
The Islet Study Group (ISG) Conference is a leading international forum dedicated to advancing islet biology and diabetes research.
010
Reposted by Lorenzo Pasquali
Parc de Recerca Biomèdica de Barcelona @prbb.org · 23/04/2026
Què fa única cada cèl·lula del pàncrees? 🤔 🧬 SPICEY ho revela identificant gens i regions reguladores de l’ADN.  Una eina nova clau per entendre millor el pàncrees en salut i diabetis  Llegeix aquí: tuit.cat/XVwdK  #DiabetesResearch #Bioinformatics  @melisupf.bsky.social
tuit.cat
Una nova eina ajuda a identificar què fa única cada tipus de cèl·lula del pàncrees - El·lipse
SPICEY, desenvolupada a MELIS-UPF, ajuda a identificar quins gens i regions reguladores són específics de cada tipus de cèl·lula als illots pancreàtics.
051
Reposted by Lorenzo Pasquali
UPF Medicine and Life Sciences @melisupf.bsky.social · 06/03/2026
#JobOffer MELIS is looking for a Junior Group Leader Position in Cell Metabolism ✅ PhD in Biology or similar; capacity to lead high-impact research projects; supervision of doctoral theses; teaching ⏰ Deadline: May 2 📍 Barcelona #PRBB Apply: apply.interfolio.com/180316 Details: bit.ly/40N09LX
078
Lorenzo Pasquali @lorenzpasquali.bsky.social · 20/02/2026
Registrations and abstract submission for the 2026 𝗘𝘂𝗿𝗼𝗽𝗲𝗮𝗻 𝗜𝘀𝗹𝗲𝘁 𝗦𝘁𝘂𝗱𝘆 𝗚𝗿𝗼𝘂𝗽 #EISG2026 are NOW OPEN Looking forward to seeing you in 𝗕𝗮𝗿𝗰𝗲𝗹𝗼𝗻𝗮! tacticsmd.net/congreso/isl...
tacticsmd.net
Islet Study Group Conference 2026
The Islet Study Group (ISG) Conference is a leading international forum dedicated to advancing islet biology and diabetes research.
031
Reposted by Lorenzo Pasquali
Gallego Lab @gallegolab.bsky.social · 16/01/2026
0/10 🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology Continuum architecture dynamics of vesicle tethering in exocytosis www.cell.com/cell/fulltex...
cell.com
Continuum architecture dynamics of vesicle tethering in exocytosis
Data from complementary imaging techniques were integrated into a model that resolves the dynamic exocyst ensemble and membrane architecture during exocytosis, an essential cellular pathway. Sec18 med...
65929
Reposted by Lorenzo Pasquali
Jorge Ferrer @jorge-ferrer.bsky.social · 23/10/2025
Many exciting opportunities for a PhD in Life Sciences in CRG, Barcelona. If you are interested in Genomics of Diabetes check out the offer for a fully funded fellowship in our lab - we will consider candidates with experimental or computational backgrounds. Please spread the word!
087
Reposted by Lorenzo Pasquali
Rada-Iglesias Lab @radaiglesiaslab.bsky.social · 06/11/2025
We recently reported that promoter competition can contribute to the robust insulation of gene regulatory domains (www.nature.com/articles/s41...). We now offer a 4-years PhD contract to investigate whether the dirsuption of this regulatory mechanism can lead to congenital defects. More details 👇
01614
Reposted by Lorenzo Pasquali
Helmholtz Munich @helmholtzmunich.bsky.social · 21/02/2025
#HelmholtzMunich Receives Funding from la Caixa Foundation to Develop Regenerative #Diabetes Therapy t1p.de/ew4iy Focus: Developing stress-resistant beta cells Goal: Overcome immune rejection & enhance #CellReplacementTherapy @heikolickert.bsky.social @lorenzpasquali.bsky.social
Helmholtz Munich Receives Funding from la Caixa Foundation to Develop Regenerative Diabetes Therapy
012
Reposted by Lorenzo Pasquali
Jorge Ferrer @jorge-ferrer.bsky.social · 02/02/2025
Still time to apply! Applications from US welcome – four years can feel longer or shorter depending on where you are 😉
01313
Reposted by Lorenzo Pasquali
Jorge Ferrer @jorge-ferrer.bsky.social · 31/12/2024
📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. Computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @crg.eu shorturl.at/O3wMi shorturl.at/ieyZy
shorturl.at
Postdoctoral scientist, gene regulatory mechanisms and diabetes | CRG Online Recruitment Portal
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
1616
Reposted by Lorenzo Pasquali
Manuel Irimia @mirimiam.bsky.social · 23/12/2024
🚨🚨🚨 If you're a bioinformatician who loves: 🧬 #SingleCell #LongReadSequencing & #AlternativeSplicing 🚀 Collaborating and travelling Apply to work with us at the spectacular BIMSB (@mdc-berlin.bsky.social) in Berlin + @upf.edu-@crg.eu in Barcelona. Qs: www.transdevolab.com Please RT! 🙏
02528
Reposted by Lorenzo Pasquali
Hans Clevers @hansclevers.bsky.social · 03/12/2024
Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. www.cell.com/cell/fulltex... New #organoid protocol allows the seemingly indefinite expansion of human fetal pancreatic Lgr5+ stem cell 1/
cell.com
Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages
Identification of an LGR5 as a marker for a tripotent stem/progenitor cell of the human fetal pancreas. Organoids derived from single LGR5+ cells are capable of long-term expansion in vitro and genera...
14315
Reposted by Lorenzo Pasquali
Heiko Lickert @heikolickert.bsky.social · 25/11/2024
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
613053
Reposted by Lorenzo Pasquali
Fabian Theis @fabiantheis.bsky.social · 20/11/2024
1/ 🧬 Single-cell genomics reveals biological variations beyond cell types. Unveiling these in separate latent dim’s is known as disentanglement. Led by @AmirAliMoinfar, we develop DRVI to learn nonlinear, disentangled & interpretable latent spaces. biorxiv.org/content/10.1101/2024.11.06.622266v1
313737