Cell extrusion is essential for homeostatic self-renewal of the intestinal epithelium. Extrusion is thought to be triggered by crowding-induced compression of cells at the intestinal villus tip. In th...

Brainshuttle™ technology by Roche enables effective medicine delivery across the blood-brain barrier, revolutionising CNS disease treatment and patient care.

Nature Medicine - Pharma and academia require different ways of working and speaking, but teamwork always wins.

‘Medicijnen ontwikkelen bij Roche is schaken in een matrix van twaalf dimensies’, zegt Hans Clevers, hoogleraar moleculaire genetica.

Identification of an LGR5 as a marker for a tripotent stem/progenitor cell of the human fetal pancreas. Organoids derived from single LGR5+ cells are capable of long-term expansion in vitro and genera...