iiinova — where your digital self keeps evolving

eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 25/04/2026

you are small. you are fragile. you are improbable. and you are enough.

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yaoi gagarin @mel.bzky.team · 27/03/2026

never thought I'd say it but if this ends in a crusade I might tentatively cheer on the catholics

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 27/03/2026

opening bluesky after months of not, to find this gem? blessed.

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🎃 Spooky Shoshana 🎃 @shoshana.bsky.social · 16/01/2026

🏳️‍⚧️ Hunter Schafer appears in a Prada ad 🏳️‍⚧️ Right-wing men: finally, they're putting hot women in ads again!

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Eziana @eziana.bsky.social · 15/01/2026

SECTOR ://EXTRACTS Chapter 2 posted! This one actually gives you a little bit instead of just being a tease 😅 www.royalroad.com/fiction/1483... www.scribblehub.com/series/21118...

royalroad.com

SECTOR ://EXTRACTS

In a not-to-distant future, a breakthrough in technology revolutionizes the computing - with a catch: it can't be turned off. From research to video games, developers use this advanced technology and ...

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Eziana @eziana.bsky.social · 15/01/2026

Can't believe I'm more nervous about putting this on AO3 than publishing it on KDP 😅 "Be kind, I'm new" archiveofourown.org/works/777374...

archiveofourown.org

Marked - Chapter 1 - Eziana - Original Work [Archive of Our Own]

An Archive of Our Own, a project of the Organization for Transformative Works

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 09/01/2026

the line that keeps going through my head and coloring my days recently has been: “I’m fine, but I’m not okay.” and…well….yeah.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 06/01/2026

i can't help but wonder if he's in to it and consented

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 06/01/2026

uhm...lemme do some math.... *a couple minutes later* about 5,000 to 5300 kcal (based on weight....which probably isn't the best weigh to do it but)

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 05/01/2026

did you know that the average adult human body contains about 125,000 to 150,000 kcal?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 05/01/2026

holy...wow. I. I'm kind of glad i have not even considered watching season five yet.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 04/01/2026

oof but fingers crossed! it must be so frustrating :/

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 04/01/2026

I was wondering what was going on with your plex server 🫂 you got this imi!!

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 04/01/2026

"In 1929, Quinn and Meyer illustrated how aspiration of these substances could occur imperceptibly: iodized oil instilled into the nose of sleeping patients was detectable on their chest roentgenograms the following morning despite an uneventful night."

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 04/01/2026

this is a paper on lipoid pneumonia; it describes what it is, how it happens, and more. an important bit: ⬇️next⬇️post⬇️

sci-hub.ru

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

*nods* but it’s still a risk that needs to be mitigated

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

the aspiration risk and concurrent risk of lipoid pneumonia means oil is a no go...

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

side note on precipitation: this not only means precipitation of the API in the spray bottle, but also at the time of spraying due to shear forces and directly on the epithelial surface; these last two can negatively impact absorption.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

sorry to leave you in suspense...but i'll finish this later, my brain needs a bit of a break. obligatory, none of this is advice, nor recommended, to anyone. this is just a fun brain puzzle.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

...that loves water. the idea would be to create a cyclodextrin inclusion system with progesterone encapsulated within. theoretically, this should solve the solubility and precipitation side of the problem. it should also help permeation and mucosa adhesion, but, if we add one more excipient.. 6/?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

cyclodextrins are cyclic oligosaccharides composed of glucose linked by glycosidic bonds. they exhibit a 3D toroidal structure with a hydrophilic outer surface and a hydrophobic cavity within, and have the ability to selectively encapsulate molecules. eli5: cyclodextrins act as a wrapper... 5/?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

thankfully, there are much better options for excipients. so. what we *need* is something to increase the solubility of progesterone in water, help permeation along, increase nasal residence(think glue,) and of course, reduce precipitation. enter cyclodextrins. 4/?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

...inconsistent dosing, and no guarantees on permeation, let alone consistent permeation; this is insufficient. (the one benefit of the excipient i used was it acts almost like glue but it can cause osmotic stress to epithelial cells and cause irritation(and damage) long term.) 3/?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

oils are not an option due to aspiration risk and risk of lipoid pneumonia, and are not (generally) used in intranasal preparations. so we're back to water-based. when i first came at this problem, it was from the angle "emulsification is sufficient for delivery"...but with dubious efficacy, 2/?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

since i'm thinking about it again...might as well post about my current thoughts on *how* to make a nasal progesterone spray work. what it comes down to is a solubilization and permeation problem. progesterone is *not* water soluble and tho it *is* oil soluble, this is not an option. 1/?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

I have always thought that a snuff bullet would work REALLY well for intranasal prog powder :3

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

ANYWAY i am pretty keen to explore powder inhalers as a delivery mechanism for progesterone.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

(this girl said 'serious' instead of 'series' lol)

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 03/01/2026

progesterone isn't water soluble, but if you can get it to stay in solution using a USP emulsifier, it kinda sorta works, though efficacy is a crap shoot. (if i could have afforded it, i would have done a serious of blood tests to see serum levels of progesterone, but alas)

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Long Lost N.P.C., PhD., BSc (Hons., Dist.), DDoS, QED, Ret. @npc.northsky.social · 01/01/2026

I did the thing. Took me long enough 😂 Would appreciate any feedback! But yeah, trigger warning - read the tags and description before jumping in. bsky.app/profile/ezia... @halfbakedrhymes.com - here ya go!

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 01/01/2026

if it drains me, defines me, and demands clarity…it’s a trap.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 31/12/2025

if there was a counter somewhere of "days with suicidal ideation in 2025" for me...it'd probably beat seattles counter of days of rain.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 31/12/2025

this, but also hopefully it comes with less suicidal ideation

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 31/12/2025

is reading and thinking about suicide throughout history a good move? maybe! it's interesting at least.

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 30/12/2025

like....of ants and dinosaurs...or maybe supernova era? or even just the three body problem? idk the microplastics are bad at making decisions

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 30/12/2025

the microplastics in my brain are telling me to reread cixin liu books...

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Reposted by eevee🏳️‍⚧️(the pokémon)

🏳️‍⚧️”Fall Futch”🦾 @faefutchauntie.bsky.social · 30/12/2025

I’m such a lil stinker

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 27/12/2025

*sends you a copy of the new york times best seller “How to Care For and Feed Your Pussy” as encouragement*

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 26/12/2025

why is it so tempting to repost things from my alt

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 26/12/2025

thinking about maybe finishing that screenplay finally...

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 26/12/2025

sometimes a girl just has to walk up to another girl and be like: 🥺 can I have a hug?

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eevee🏳️‍⚧️(the pokémon) @literallyjustapokemon.online · 25/12/2025

OH! ALSO!!! “did you know that elves are carnivores? and also ambush predators?…really reframes elf on a shelf….”

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