Reposted by Fabio Barteri
🧬 A gene atlas from 17 mouse lines
Researchers built an atlas of over 1,000 brain samples from mice carrying autism risk genes, sorting them by how the genes actually behave rather than which mutation they carry.
🔗 doi.org/10.1126/science.adz6688
#Genetics #Autism #Science 🧪
doi.org
Transcriptome-based classification in mice with ASD-risk mutations
Autism spectrum disorder (ASD) is a neurodevelopmental condition with a strong genetic component. Large-scale human genetic studies have identified >1200 ASD-risk genes. We report a sex-balanced atlas...