Detonation of newly discovered ‘ruptoblasts’, found in flatworms, releases compounds that kill nearby cells in minutes.

Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.

Stefins, members of the cystatin superfamily, regulate cysteine proteases, yet their roles in early-branching metazoans remain poorly defined. Here, w…

Fish poxviruses are increasingly recognised as emerging pathogens of fish and should be considered in cases of unexplained gill or skin pathology. Carp edema virus (CEV), the causative agent of koi s...

Carp edema virus (CEV) infects the common carp (Cyprinus carpio) and causes the lethal koi sleepy disease (KSD). Signs of KSD include respiratory, detoxification, and osmoregulatory difficulties. Sal...

The gut microbiota, immune system, and enteric nervous system interact to regulate adult gut physiology. However, the mechanisms establishing gut physiology during development remain unknown. We repor...

Infectious Hematopoietic Necrosis Virus (IHNV) is a significant economic threat to salmonid aquaculture worldwide. Understanding the factors that infl…

Cysteine cathepsins are central regulators of lysosomal proteolysis, immune and metabolic homeostasis, yet the evolutionary forces shaping their diversificat...

This book explores diverse strategies to combat diseases in aquaculture and effectively manage fish health for sustainable farming practices. It addresses the

The ability to profile gene expression at the single cell level can offer unprecedented insight into the vertebrate immune system. While such profiling of non-model organisms can present unique challe...

In the past three decades, fish abundance, richness and uniqueness have diverged across cold and warm streams, and the effects on native fish communities of stream warming and increases in introduced fishes have magnified each other.

An automated tool (EPP) identifies distinct cell phenotypes in flow cytometry data through optimized 2D gating as shown in 4 published datasets. EPP’ C++ code integrates with any software, as demonstr...

Interact-omics, a high-throughput cytometry-based framework, resolves the cellular interaction landscape.

Abstract. Horizontal gene transfer (HGT) is less frequent in eukaryotes than in prokaryotes, yet can have strong functional implications and was proposed a

Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.

A curated gene list for teleost fish transcriptomics enhances the interpretation of high volumes of data by focusing on key biological processes. This resource bridges gaps in automated annotations, ....

Limited color channels in fluorescence microscopy have long constrained spatial analysis in biological specimens. Here, we introduce cycle Hybridization Chain Reaction (HCR), a method that integrates ...

Welcome to the Lab of Fish Immunology at the Biology Centre CAS