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Kauê Machado Costa

@kmcostalab.com
788 followers 384 following 90 posts

Neuroscientist 🧠 Brazilian Assistant Professor at UAB Dept. of Psychology Allen Institute Next Generation Leader Interested in dopamine, cortex, learning, cognition, and more kmcostalab.com

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Kauê Machado Costa @kmcostalab.com · 01/09/2026
Minimal qualifications include experience with rodent behavior, fiber photometry, and Matlab/Python programming, or rodent alpha-synuclein models of Parkinson's disease. Priority will be given to candidates with both sets of expertise and a good publication record
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Kauê Machado Costa @kmcostalab.com · 01/09/2026
My lab is looking for a new postdoc (or exceptional grad student) to tackle an interesting hypothesis on Parkinson's disease and learning. The position is funded and we are looking for someone that can start ASAP. See thread, and please follow these instructions to apply: www.kmcostalab.com/join-us
kmcostalab.com
K.M. Costa Lab - Join us
Join
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Kauê Machado Costa @kmcostalab.com · 26/08/2026
@uabneuro.bsky.social
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Kauê Machado Costa @kmcostalab.com · 26/08/2026
Great updates! Our exceptional undergraduate researcher, Eli Mrug, received both a Trainee Professional Development Award from the @sfn.org and a poster award at the meeting of the Alabama Psychological Association! The #TPDA will help him present his exciting new work at #SFN - preprint out soon! 😃
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Kauê Machado Costa @kmcostalab.com · 21/08/2026
New milestone achieved: the lab has filed its first patent!!! More details later, but I wanted to share how terrific it was to work with my grad student, Jeff Horbatiuk, on this invention! We envision it will have interesting applications in behavior research, and potentially industry and medicine
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Kauê Machado Costa @kmcostalab.com · 16/08/2026
There is nothing better than to see our trainees develop and thrive. Super proud of my postdoc, Dr. Biru Dudhabhate, for receiving this great award! www.uab.edu/medicine/new...
uab.edu
Dudhabhate and Jones-Muhammad named Emerging Scholar Award winners for 2026-2027 | Heersink School of Medicine News
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Reposted by Kauê Machado Costa
ACNP @acnporg.bsky.social · 06/08/2026
Please join us in Congratulating the 2026 ACNP Travel Award Class! 👏🤩 Click Here ➡️ tinyurl.com/5bzaz8va for more information on Travel Awards. 📝
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Kauê Machado Costa @kmcostalab.com · 29/07/2026
I am super grateful and honored to have been selected for an ACNP travel award! This will have an important impact for me and my lab. Looking forward to exciting conversartions in San Diego next year! @uabneuro.bsky.social @acnporg.bsky.social
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Kauê Machado Costa @kmcostalab.com · 14/07/2026
static.klipy.com
Leonardo DiCaprio's Congrats Toast
ALT: Leonardo DiCaprio's Congrats Toast
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Kauê Machado Costa @kmcostalab.com · 03/07/2026
Congrats Nao!!!
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Kauê Machado Costa @kmcostalab.com · 28/06/2026
Matéria na @folha.com sobre minha nomeação para o grupo de Young American Scientists da @sciam.bsky.social 🇧🇷🇺🇲 Agradeço à Ana Bottallo pelo trabalho no artigo, e espero que outros jovens brasileiros também venham a se interessar pelo meu tópico de pesquisa. www1.folha.uol.com.br/ciencia/2026...
www1.folha.uol.com.br
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Reposted by Kauê Machado Costa
UAB Comprehensive Neuroscience Center @uabneuro.bsky.social · 18/06/2026
Story from @sciam.bsky.social on CNC faculty member Dr. Kauê Costa (@kmcostalab.com), who was included in the 2026 "Young American Scientists" selection of groundbreaking researchers that represent the future of science, technology and medicine! www.scientificamerican.com/podcast/epis...
scientificamerican.com
This young neuroscientist is challenging what we know about learning
Neuroscientist Kauê M. Costa talks about surprising results that are changing how we think dopamine works and how the brain really learns
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Kauê Machado Costa @kmcostalab.com · 16/06/2026
More info on the program and other awardees here: scientificamerican.com/report/young... yahoo.com/news/science...
scientificamerican.com
The Young American Scientists
Meet the researchers who may one day change the world
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Kauê Machado Costa @kmcostalab.com · 16/06/2026
I'm honored to be one of the first @sciam.bsky.social Young American Scientists! Big thanks to Geoff Schoenbaum and other mentors, colleagues, and trainees. Science is a group effort and I'm lucky to have had great collaborators! @uabneuro.bsky.social www.scientificamerican.com/article/kaue...
scientificamerican.com
Kauê M. Costa
Applying new tools to behavioral tests to discern how we learn
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Kauê Machado Costa @kmcostalab.com · 13/05/2026
To recap, we found that KChIP4a controls inhibition in mesolimbic dopamine neurons and shapes learning from negative prediction errors. This impacts how we understand the specialization of dopamine neuron subpopulations, how they compute prediction errors, and potentially their role in disease.
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Kauê Machado Costa @kmcostalab.com · 13/05/2026
I'm so happy to have my work featured as cover article in the Journal of Neuroscience!!! It is a fantastic honor! Big thanks to all the co-authors, especially Tamara Müller, and the journal editors. www.jneurosci.org/content/46/1... @sfnjournals.bsky.social @sfn.org @uabneuro.bsky.social
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Kauê Machado Costa @kmcostalab.com · 09/05/2026
Congrats Laura - putting it on my lab's JC list
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Kauê Machado Costa @kmcostalab.com · 07/05/2026
NEW PAPER! Here, my postdoc, Biru Dudhabhate, and I review the history of one of the most famous neuroscience hypotheses, the dopamine reward prediction error, and reflect on what made it such a major advance for the field. @uabneuro.bsky.social www.frontiersin.org/journals/com...
frontiersin.org
Frontiers | A brief history of dopamine prediction errors
Dopamine signaling has become closely associated with reward prediction errors (RPEs)–the difference between expected and experienced value. Although not wit...
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Kauê Machado Costa @kmcostalab.com · 01/05/2026
Congrats man!
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Kauê Machado Costa @kmcostalab.com · 24/04/2026
This is super interesting Jeremy! Will take a deep look into it. Seems like both subpopulations would be canonical dopamine neurons (sag currents, prominent AHP, rebound firing), but slightly tuned... Very cool!
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Kauê Machado Costa @kmcostalab.com · 22/04/2026
I have been working on this since my doctoral work at @mpibrain.bsky.social and @goetheuni.bsky.social. I am so thrilled to have it finally in a good home 😁 @uabcappi.bsky.social @uabcnbci.bsky.social
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Kauê Machado Costa @kmcostalab.com · 22/04/2026
NEW PAPER! Our study, in the pipeline for years and now out in #JNeurosci, shows that a channel subunit called KChIP4a is a biophysical amplifier of inhibition and controls learning from negative experiences! @uabneuro.bsky.social @sfnjournals.bsky.social www.jneurosci.org/content/earl...
jneurosci.org
KChIP4a is a biophysical amplifier of inhibition in atypical dopamine neurons and controls learning from negative prediction errors
Dopamine neurons projecting to distinct brain regions have unique biophysical properties, which is thought to reflect functional specialization. One defining feature is the duration of hyperpolarizati...
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Kauê Machado Costa @kmcostalab.com · 20/04/2026
Thanks! That's wonderful feedback 😄
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Kauê Machado Costa @kmcostalab.com · 16/04/2026
This Sunday I'll be at @sidewalkfilm.bsky.social , doing a a post-screening discussion of "Ratatouille". This is part of the Science on Screen initiative (scienceonscreen.org). I am more than happy to get to talk about how rats are cool and smart 😁 sidewalkfest.com/events/ratat...
sidewalkfest.com
Science on Screen® 2026: Ratatouille (2007) with Dr. Kauê M. Costa – Sidewalk Film
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Kauê Machado Costa @kmcostalab.com · 14/04/2026
Thanks Alicia 😁
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Kauê Machado Costa @kmcostalab.com · 14/04/2026
Thanks Laura! We are really excited about this project. High risk, high reward for sure
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Kauê Machado Costa @kmcostalab.com · 13/04/2026
Thanks Drew!
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Kauê Machado Costa @kmcostalab.com · 13/04/2026
Late announcement (due to distraction), but I am happy to share that the lab, together with our great collaborator Nuria Vendrell-Llopis, was awarded an NIMH R21! We are super excited to test some new ideas about how dopamine drives learning in brain computer interfaces! 🧠🖥️ @uabneuro.bsky.social
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Kauê Machado Costa @kmcostalab.com · 13/03/2026
... even if you miss other rewards? 😆😆😆 Seems like the investigator became the subject
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Kauê Machado Costa @kmcostalab.com · 12/03/2026
Super cool work Laura!
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Kauê Machado Costa @kmcostalab.com · 06/02/2026
It was a great pleasure! Wonderful to have you here :)
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Kauê Machado Costa @kmcostalab.com · 06/02/2026
Permanent, and a core part of Birmingham's identity. It's a very nice place. But don't tell anyone please, otherwise cost of living and traffic will go up 🤣
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Reposted by Kauê Machado Costa
The Transmitter @thetransmitter.bsky.social · 20/01/2026
In this month’s “Liftoff,” @shawnrhoadsphd.com talks about how he’ll implement hackathons to foster community in his lab, and @zurisullivan.bsky.social shares how weekly discussions about unfamiliar topics can encourage curiosity in a lab. bit.ly/3ZkMQl8 By @franciscorr25.bsky.social #neuroskyence
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Kauê Machado Costa @kmcostalab.com · 18/01/2026
Sounds like a great opportunity!
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Thank you Nao! You know, this made me reminisce on the past, and I remembered the impact you had on me as a graduate student when you did that sabbatical in Jochen's lab. Still remember your master class on TDRL and dopamine. Good times! 😀
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Thank you Nicole!
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Thank you so much Alicia!
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Thank you Ali!
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Thanks Drew!
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Thanks so much Phil!
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
@uabneuro.bsky.social @mpibrain.bsky.social @ufpa.bsky.social @uspoficial.bsky.social
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Kauê Machado Costa @kmcostalab.com · 14/01/2026
Big News! I am beyond honored to have received the American Psychological Association Distinguished Scientific Award for Early Career Contributions to Psychology in animal learning and behavior! I am so grateful to my lab, mentors, colleagues, and institutions for all the support over the years!
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Kauê Machado Costa @kmcostalab.com · 30/12/2025
Fantastic @arifahamid.bsky.social ! Gonna aim to go through it over the new year 😁
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Reposted by Kauê Machado Costa
The Transmitter @thetransmitter.bsky.social · 26/11/2025
@thetransmitter.bsky.social’s “New Lab Directory” features a list of new neuroscience labs that opened in 2024-2025, and some set to launch in 2026. Check out the list to learn about the work of more than 50 new neuroscience labs. www.thetransmitter.org/community/th... #StateOfNeuroscience
thetransmitter.org
The Transmitter’s New Lab Directory
Learn about neuroscience labs launched in the past two years, plus a few opening their doors in 2026.
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Kauê Machado Costa @kmcostalab.com · 26/11/2025
Fantastic @naoshigeuchida.bsky.social ! Congrats!
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Kauê Machado Costa @kmcostalab.com · 20/11/2025
Most definitely (and I think it is at least "incomplete"), but that's true of all discoveries. That's somewhat orthogonal to impact, predictive power, and general inspiration for new work.
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Kauê Machado Costa @kmcostalab.com · 20/11/2025
The RPE hypothesis of dopamine function. Hard to think of a basic theoretical mechanism that had a bigger impact in the field, except maybe the Hodgkin-Huxley model
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Kauê Machado Costa @kmcostalab.com · 14/11/2025
Thanks UAB reporter for the very enthusiastic article 😁 www.uab.edu/reporter/res... @uabneuro.bsky.social @parkinsondotorg.bsky.social
uab.edu
This “dopamine aficionado” is exploring new approaches to a Parkinson’s puzzle
This “dopamine aficionado” is exploring new approaches to a Parkinson’s puzzle
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Kauê Machado Costa @kmcostalab.com · 14/11/2025
Heading to SFN - I'll be at the UAB graduate fair stand on Sunday from 12-1pm, and otherwise open to talk shop with any prospective graduate student, postdoc, or trainnee. Feel free to message me if you are interested in the lab's work 😁 #Sfn2025 #SfN25 #SFN
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Kauê Machado Costa @kmcostalab.com · 11/11/2025
Always the best work Nic - absolutely great!
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