Reposted by Arrosan Rajalingam
Happy to share the first preprint from our lab, led by @arrosan.bsky.social, in collaboration with @ccb-lab.bsky.social. We identify a conserved cohesin-interacting motif in Red1 required for its recruitment, DSB formation, and Mek1 activation.
www.biorxiv.org/content/10.6...
#meiosis #recombination
biorxiv.org
Cohesin–axis interaction via a conserved Red1 motif promotes domain-specific DSB formation and Mek1 activation
Faithful chromosome segregation during meiosis I requires tight control of interhomolog recombination. In budding yeast, the meiotic chromosome axis, built on Rec8-containing cohesin together with Red...
