Multiomic profiling provides a comprehensive physiological overview at the molecular level, but understanding of its spatiotemporal dynamics remains limited in human populations. We profiled longitudi...

Rosen et al. quantify how eQTL study sample size influences signal discovery and GWAS colocalization. Integrating evidence from recent eQTL studies, they show that limited statistical power influences...

PhD programme in human genetics, AI and multi-omics to uncover causal biology and accelerate therapeutic target discovery with academic and industry partners.

A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.

A combination of whole-genome NanoSeq with deep whole-exome and targeted NanoSeq is used to accurately characterize mutation rates and genes under positive selection in sperm cells.

Trainee Excellence Spotlight, TES, Trainee, Spotlight, ASHG, American Society for Human Genetics, Genetics

PhD Project - Interaction of genetic and environmental drivers of metabolic and autoimmune disease at University of Dundee, listed on FindAPhD.com

Nature Genetics - This study introduces AdipoExpress, an eQTL meta-analysis of 2,344 subcutaneous adipose tissue samples, which triples the size of previous studies and expands the discovery of...

As we age, many tissues become colonised by microscopic clones carrying somatic driver mutations ([1][1]–[10][2]. Some of these clones represent a first step towards cancer whereas others may contribu...