A long-range inhibitory projection from the basal forebrain disinhibits the cortex to amplify sensory responses. This circuit encodes motivational salience and predicts moment-to-moment attentional pe...

The Department of Neuroscience and Cell Biology at Rutgers Robert Wood Johnson Medical School (RWJMS), the Rutgers Child Health Institute (CHI), and the Rutgers Brain Health Institute (BHI) seek appli...

Cachexia, a severe wasting syndrome associated with inflammatory conditions, often leads to multiorgan failure and death. Patients with cachexia experience extreme fatigue, apathy, and clinical depres...

A distinct subpopulation of neurons in the rat orbitofrontal cortex encodes reward history at the time of choice, providing a potential neural substrate by which reward history may influence decisions...

Frontal cortex neurons can be grouped into categorical response types corresponding to particular decision variables, such as reward size, decision confidence, or value, and individual variables may b...