From May 18 to 21, 2027, Wrocław will host the 12th International γδ T Cell Conference, a leading global meeting for researchers studying γδ T cells – immune cells with tremendous therapeutic potentia...

The success of cancer immunotherapy depends on the mobilization of leukocytes with the capacity to eliminate tumor cells. γδ T cells represent a lymphocyte lineage with strong cytotoxic potential and ...

The human TCRγδ constant region modulates T cell activation and corresponds with T cell clonal expansion and function.

Sepsis-associated encephalopathy (SAE) is a severe and often fatal consequence of sepsis. Here authors show in a mouse model of sepsis that γδ T17 cells, migrating from the small intestine to the meni...

Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.

Here, the authors use a double-reporter system to tag IFNγ-producing versus IL-17A-producing γδ T cells to compile a trancriptomic resource of these cell subsets in mice at steady state and in respons...

Under steady-state conditions, γδ T cell expansion is minimal; however, upon infection with L. amazonensis, there is a marked increase in IL-17-producing γ

Signaling lymphocytic activation molecule family 7 (SLAMF7), an important therapeutic target of myeloma cells, is highly expressed in osteoclasts. Ex vivo-expanded human Vγ9Vδ2 T cells are able to ef...

Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome.