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Jean-Philippe Nougayrede

@jpnoug.bsky.social
36 followers 53 following 5 posts
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Reposted by Jean-Philippe Nougayrede
Andreas Bäumler @abaumler.bsky.social · 13/09/2025
Hydrogen sulfide production distinguishes Salmonella from close relatives, but its biological significance remains obscure. This study uncovers the secret: Salmonella uses hydrogen sulfide production as a weapon to outcompete E. coli and gain a foothold in the gut. www.pnas.org/doi/10.1073/...
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Reposted by Jean-Philippe Nougayrede
Benoit Pons @benoitjpons.bsky.social · 04/09/2025
How do bacteria choose what type of defences to use against phages? We explored that question in the last paper I worked on as a postdoc at the Uni of Exeter @uniofexeteresi.bsky.social with Stineke van Houte, Stefano Pagliara and Edze Westra (not on Bluesky) doi.org/10.1098/rstb...
doi.org
Phage provoke growth delays and SOS response induction despite CRISPR-Cas protection | Philosophical Transactions of the Royal Society B: Biological Sciences
Bacteria evolve resistance against their phage foes with a wide range of resistance strategies whose costs and benefits depend on the level of protection they confer and on the costs for maintainance....
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Jean-Philippe Nougayrede @jpnoug.bsky.social · 25/06/2025
Il y a des scripts "glow up effect" qui pourraient faire l'affaire
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Reposted by Jean-Philippe Nougayrede
Ted Pavlic (he/him/his) @tedpavlic.bsky.social · 08/06/2025
Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪 www.richmondscientific.com/how-a-discov...
richmondscientific.com
How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific
A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.
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Reposted by Jean-Philippe Nougayrede
Curly sue @moocowsue.bsky.social · 29/05/2025
Just in case you’ve never heard of Lysenko www.theatlantic.com/science/arch...
theatlantic.com
The Soviet Era's Deadliest Scientist Is Regaining Popularity in Russia
Trofim Lysenko’s spurious research prolonged famines that killed millions. So why is a fringe movement praising his legacy?
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Reposted by Jean-Philippe Nougayrede
IPBS Toulouse @ipbstoulouse.bsky.social · 17/05/2025
🚨 PhD opportunity in Toulouse! Join a dynamic team to study membrane proteins & transporters of therapeutic interest using cryo-EM, enzymology & biophysics. 📅 Deadline: June 19, 2025 🔗 Funded by @frm-officiel.bsky.social #StructuralBiology #MicroSky More details 👇 shorturl.at/OaVMI
shorturl.at
PhD position in structural biology and infectious diseases - IPBS-Toulouse
We are currently looking for highly motivated PhD student with a strong interest in structural[…]
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Reposted by Jean-Philippe Nougayrede
Rafael Peña-Miller @penamiller.bsky.social · 15/05/2025
New preprint led by @brunoluviano.bsky.social & Fernando Santos. We show that filamentation enhances bacterial survival under toxic stress — not as collateral damage, but as a regulated morphological response. TL;DR: Filamentation isn’t a symptom, it’s a strategy! www.biorxiv.org/content/10.1...
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Jean-Philippe Nougayrede @jpnoug.bsky.social · 07/05/2025
A nice review with the latest advances and views on our favourite genotoxin !
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Reposted by Jean-Philippe Nougayrede
Lars Vereecke @larsvereecke.bsky.social · 06/05/2025
🔬 New review out in Trends in Microbiology! Together with @MaudeJans , we explore the physiological factors driving pks+ E. coli expansion and colibactin exposure in colorectal cancer. read the full story: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F... #ColorectalCancer #Ecoli #Genotoxins
kwnsfk27.r.eu-west-1.awstrack.me
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Reposted by Jean-Philippe Nougayrede
Olivier Neyrolles @oneyrolles.bsky.social · 06/05/2025
Happy to share Saurabh's latest review on the bacterial exometabolome and its role in virulence and pathogenesis, just out in @cp-trendsmicrobiol.bsky.social — and it’s open access! 😉 👏 @saurabhchugh09.bsky.social www.cell.com/trends/micro...
cell.com
The exometabolome as a hidden driver of bacterial virulence and pathogenesis
The traditional view of metabolism as merely supplying energy and biosynthetic precursors is undergoing a paradigm shift. Metabolic dynamics not only regulates gene expression but also orchestrates ce...
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Reposted by Jean-Philippe Nougayrede
Melanie Blokesch @mblokesch.bsky.social · 25/04/2025
Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩 Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭! Please visit my lab's webpage for details about the position and how to formally apply.
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Reposted by Jean-Philippe Nougayrede
Matt Bogyo @mbogyo.bsky.social · 19/04/2025
If you are interested in lipids in bacteria, check out this awesome new review written by my talented student Alyssa Carter, super postdoc Emily Woods and me. #chembio www.sciencedirect.com/science/arti...
sciencedirect.com
Chemical strategies for targeting lipid pathways in bacterial pathogens
Microbial pathogens continue to plague human health and develop resistance to our current frontline treatments. Over the last few decades, there has b…
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Jean-Philippe Nougayrede @jpnoug.bsky.social · 03/04/2025
Magnifique, merci pour le partage !
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Reposted by Jean-Philippe Nougayrede
Ronan Kapetanovic @ronankp.bsky.social · 27/03/2025
We are looking for a PhD candidate starting on the 01-10-2025. The project aims to understand how the host cells use copper and oxidative species to fight Salmonella infection and how this pathogen evades this antimicrobial response. SHORT DEADLINE ! 20-04-2025 jobs.inrae.fr/en/ot-25517
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Reposted by Jean-Philippe Nougayrede
Typas Lab @typaslab.bsky.social · 16/12/2024
You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology! Registration: 1 Apr 2025 Course: 03 – 11 Sep 2025 | Spetses, Greece meetings.embo.org/event/25-new...
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Reposted by Jean-Philippe Nougayrede
Carl T. Bergstrom @carlbergstrom.com · 19/03/2025
1. For the past thirty years I've had the best job in the world. 
I've had the opportunity to follow my curiosity; explore the workings of nature and society; mentor students and junior colleagues in the same process; and teach generations of students about it all.
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Jean-Philippe Nougayrede @jpnoug.bsky.social · 08/03/2025
But the teams and companies that use it as a therapeutic chassis are beginning to take it into account, using mutants that no longer produce the genotoxin. A clinical trial is currently underway with one of these mutants.
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Jean-Philippe Nougayrede @jpnoug.bsky.social · 08/03/2025
Hi Xavier ! Ha, it's been considered and advertised as safe for so long (even after publications on Mutaflor's production of colibactin) that the message of its gentoxicity has had trouble getting through.
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