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Philipp Klein

@jpkhl.bsky.social
101 followers 57 following 113 posts

A scientist practicioner researching psychotherapy. For details, see www.researchgate.net/profile/Jan-Kl… l

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Philipp Klein @jpkhl.bsky.social · 09/02/2026
The effect on interpersonal functioning was also present in individuals using the digital intervention.
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
www.researchgate.net/publication/...
researchgate.net
Treatment modifiers of interpersonal functioning in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Request PDF
Request PDF | On Jan 31, 2026, Johanne Pereira Ribeiro and others published Treatment modifiers of interpersonal functioning in psychotherapy for people with borderline personality disorder: Systemati...
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
I am grateful for the opportunity to contribute to this study and congratulations to Johanne who has just successfully completed her PhD with this project and started a postdoc position at Aalborg University!
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
They found that psychotherapy for BPD did improve interpersonal functioning, maybe particularly strongly in individuals also suffering from anxiety disorders or an overall greater number of co-occuring disorders.
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
The psychotherapies employed included Mentalization-Based Therapy (MBT) and Dialectical Behavioral Therapy (DBT) but also a digital intervention based on Schema Therapy, priovi.
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
Therefore, Johanne Pereira Ribeiro from Denmark and colleagues conducted an individual patient data meta-analysis (IPD-MA) including more than 2700 participants from 32 RCTs were psychotherapy was compared to treatment as usual (TAU) or clinical management (CM).
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
It is unclear if psychotherapy for BPD also has an effect on interpersonal functioning and whether this effect is stronger in certain individuals.
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Philipp Klein @jpkhl.bsky.social · 09/02/2026
Psychotherapy for Borderline Personality Disorder (BPD) does have an effect on overall symptoms of BPD. But individuals with BPD often suffer from interpersonal difficulties and these can severely affect daily functioning.
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Philipp Klein @jpkhl.bsky.social · 03/02/2026
I am grateful to have had the opportunity to contribute to this important study. www.nature.com/articles/s41...
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Philipp Klein @jpkhl.bsky.social · 03/02/2026
This trial published today in found that individuals who use the DMHI mylovia reported greater improvements in sexual functioning than those who received treatment as usual (which, for many, meant no treatment at all) with a medium effect size (d = 0.51).
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Philipp Klein @jpkhl.bsky.social · 03/02/2026
Overall, this „treatment gap“ is more than 50%, but it is especially pronounced for female sexual dysfunction, possibly because patients (and sometimes also their therapists) can be reluctant to talk about sexual health.
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Philipp Klein @jpkhl.bsky.social · 03/02/2026
One of the main advantages of Digital Mental Health Interventions (DMHIs) is their ability to reach individuals who would otherwise never receive treatment.
nature.com
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Philipp Klein @jpkhl.bsky.social · 03/01/2026
Perfect, thanks Tim! I came across that paper but then lost it. Glad you helped me find it again!
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Philipp Klein @jpkhl.bsky.social · 03/01/2026
Gerade entdeckt: Das Buch ist ab jetzt als E-Book verfügbar, ab Mitte des Monats auch gedruckt. Bin aufgeregt, dass es endlich soweit ist und unendlich dankbar allen, die dazu beigetragen haben. link.springer.com/book/10.1007...
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Philipp Klein @jpkhl.bsky.social · 03/01/2026
@tkaiser.science do you also have the link to the paper from the perspective of radical behaviorism? Thanks!
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Reposted by Philipp Klein
Johannes C. Ehrenthal @ehrenthal-lab.bsky.social · 31/12/2025
Cord Benecke (1965-2025).
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Philipp Klein @jpkhl.bsky.social · 27/12/2025
You can register here: contextualscience.org/the_cbs_supe... @myacbs.bsky.social @michael.muthukrishna.com
contextualscience.org
The CBS Superlab
What is the CBS Superlab? With the release of the ACBS Task Force Report on the Strategies and Tactics of Contextual Behavioral Science Research, high-level discussion around how to roll out the propo...
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Philipp Klein @jpkhl.bsky.social · 27/12/2025
I am extremely grateful that I will have the opportunity to present this CBS Superlab with Michael Muthukrishna, Sigal Zilcha-Mano, Steven C. Hayes and Kirk Strosahl. It will be one of my highlights of 2026.
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
Congratulations Johanne on this excellent work! It was a pleasure being a contributor to this study; I particularly admired your attentiveness to detail and the skilfulness in integrating the numerous perspectives we co-authors offered in the writing process. Well done! bit.ly/4p8dPMp
bit.ly
Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Request PDF
Request PDF | Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Backgroun...
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
Most patients included in this IPD-MA were treated with either Dialectical Behaviour Therapy (DBT), Mentalization Based Therapy (MBT) or a digital intervention based on Schema Therapy (priovi). The treatment effect was not affected by whether the treatment was online or in person.
bit.ly
Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Request PDF
Request PDF | Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Backgroun...
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
Psychotherapy seemed to be less effective for individuals who also suffered from depression or reported sexual abuse.
bit.ly
Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Request PDF
Request PDF | Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Backgroun...
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
This IPD-MA looked at numerous patient characteristics and found that borderline patients with comorbid anxiety disorder or comorbid substance use disorder derive the greatest benefit from psychotherapy.
bit.ly
Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Request PDF
Request PDF | Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Backgroun...
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
IPD-MA are better than conventional meta-analyses at identifying which patient groups benefit most from a given treatment.
bit.ly
Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Request PDF
Request PDF | Treatment moderators of symptom severity in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data | Backgroun...
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
Psychotherapy for individuals with Borderline Personality Disorder is effective, maybe more so when certain comorbidities are present. That is the result of a large individual participant data meta-analysis (IPD MA) just published by Johanne Pereira Ribeiro Psychotherapy and Psychosomatics.
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Philipp Klein @jpkhl.bsky.social · 19/11/2025
Ach, danke für die Rückmeldung! Und: schönen Abend :-)
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
bit.ly/43tE6fa
bit.ly
Psychische Inflexibilität, widrige Kindheitserfahrungen und Symptomschwere.
Download Citation | Psychische Inflexibilität, widrige Kindheitserfahrungen und Symptomschwere. | Fragestellung Wie hängen widrige Kindheitserfahrungen (adverse childhood experiences, ACE), psychopath...
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Herzlichen Dank, liebe Sophia, dass Du diese wunderbare Arbeit geschrieben und mit großem Engagement veröffentlicht hast! Und ein besonderer Dank auch an die Universität zu Lübeck und die addisca Stiftung, welche diese Studie fördern.
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Oder in Alltagssprache gesprochen: wenn diese widrigen Kindheitserfahrungen sehr im Mittelpunkt des Erlebens stehen, dann sind möglicherweise auch psychische Probleme stärker ausgeprägt.
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Zusammen mit ausgeprägten Schwierigkeiten, belastende Gedanken und Gefühle loszuwerden, hängt diese Art des Selbstbildes mit der Schwere einer Reihe von psychischen Problemen zusammen, unter anderem mit Depressivität und Ängstlichkeit.
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Das Ergebnis: Veränderungen des Selbstbild („Ich sollte nicht so fühlen und denken, wie ich das tue“) hängen besonders stark mit widrigen Kindheitserfahrungen wie emotionalen Missbrauch zusammen (als beispielsweise der Erfahrung, als dumm, faul oder hässlich bezeichnet zu werden).
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Genau das hat Sophia Singer im Rahmen ihrer Masterarbeit gemacht.
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Eine Möglichkeit, der Antwort näher zu kommen ist, die Kindheitserfahrungen, die Schwere der Symptome und mögliche Prozesse, die zwischen beidem vermitteln, als Netzwerk zu betrachten. Dann bekommt man rasch einen Überblick, wie diese Dinge zusammenhängen könnten.
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Philipp Klein @jpkhl.bsky.social · 14/11/2025
Wie kommt es, dass Menschen, die widrige Kindheitserfahrungen erlebt haben, auch stärker unter psychischen Erkrankungen leiden?
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Reposted by Philipp Klein
Tim Kaiser @tkaiser.science · 24/10/2025
New paper led by Nele Assmann, in which we used causal forests to test the heterogeneity of treatment effects of Schema Therapy vs. DBT for severe Borderline Personality Disorder.
sciencedirect.com
Differential effectiveness of dialectical behavioral therapy and schema therapy in patients with borderline personality disorder: a secondary analysis of a randomized clinical trial
Borderline personality disorder (BPD) can be treated successfully with specific psychological treatments, but there is no clear evidence of superiorit…
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Reposted by Philipp Klein
Julia M. Rohrer @dingdingpeng.the100.ci · 21/10/2025
The recording is now available so that you can confirm that I indeed have a German accent and color-match my outfits with my Zoom background. youtu.be/YL0co26ng-g?...
youtu.be
CIIG Seminar: Julia Rohrer | Making Rigorous Causal Inference More Mainstream | 20 Oct 2025
YouTube video by the Causal Inference Interest Group (CIIG)
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Philipp Klein @jpkhl.bsky.social · 18/10/2025
A number of studies have compared digital interventions to CBT. Both are about equally effective, meta-analyses suggest. But obviously, we also have to consider preferences: digital interventions are less effective in individuals who prefer f2f-therapy. References: bit.ly/DiGA_2024
bit.ly
(PDF) State of the Art: Internetbasierte Behandlung für Psychische Störungen. Teil 1: Selbstmanagement-Interventionen (SMI) / Digitale Gesundheitsanwendungen (DiGA)
PDF | Es gibt zahlreiche internetbasierte Selbstmangementinterventionen zur Behandlung psychischer Störungen. Wenn sie gut gemacht sind, basieren sie... | Find, read and cite all the research you need...
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Philipp Klein @jpkhl.bsky.social · 15/10/2025
In this small single-arm observational study we found similar adherence and pre-post effect sizes as in our RCTs: pubmed.ncbi.nlm.nih.gov/32874927/
pubmed.ncbi.nlm.nih.gov
Feasibility, effectiveness and safety of the self-management intervention deprexis in routine medical care: Results of an uncontrolled observational study - PubMed
This non-interventional study conducted in outpatient practices confirms results from numerous RCTs. Taken together, these data show that deprexis can be used effectively and safely in the routine car...
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Philipp Klein @jpkhl.bsky.social · 13/10/2025
This strengthens the recommendation for using unguided digital interventions in the treatment of depression.
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Philipp Klein @jpkhl.bsky.social · 13/10/2025
Thank you for the opportunity to contribute to this project! www.researchgate.net/publication/...
researchgate.net
(PDF) Effectiveness of unguided web-based interventions for the treatment of depressive symptoms in improving the quality of life: a meta-analysis
PDF | Purpose Unguided internet-based interventions (IBIs) have proven to be effective in reducing depressive symptoms. The primary objective of this... | Find, read and cite all the research you need...
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Philipp Klein @jpkhl.bsky.social · 13/10/2025
A recent meta-analysis by Felix Butt from Stephan Köhler`s research group at Charité, Berlin, suggests that unguided digital interventions have effects both quality of life might and on depression (g = 0.29 / 0.37).
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Philipp Klein @jpkhl.bsky.social · 13/10/2025
Many researchers as well as clinicians and their patients would argue that an evidence-based intervention should show effects both on symptoms and on functional outcomes to receive a strong recommendation for use.
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Philipp Klein @jpkhl.bsky.social · 13/10/2025
It is well-established that unguided digital interventions are effective in reducing symptoms of depression. But what about the effect on quality of life?
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Reposted by Philipp Klein
Julia M. Rohrer @dingdingpeng.the100.ci · 06/10/2025
Happy to announce that I'll give a talk on how we can make rigorous causal inference more mainstream 📈 You can sign up for the Zoom link here: tinyurl.com/CIIG-JuliaRo...
Causal inference interest group, supported by the Centre for Longitudinal Studies

Seminar series
20th October 2025, 3pm BST (UTC+1)

"Making rigorous causal inference more mainstream"
Julia Rohrer, Leipzig University

Sign up to attend at tinyurl.com/CIIG-JuliaRohrer
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Philipp Klein @jpkhl.bsky.social · 03/10/2025
Digging somewhat deeper: Judea Pearl, the pioneer of modern causal inference: youtu.be/MNyI1Xkapxg?...
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Philipp Klein @jpkhl.bsky.social · 01/10/2025
And about to inaugurate a new head of state this coming weekend, I just learned
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Philipp Klein @jpkhl.bsky.social · 26/09/2025
@mayer-l.bsky.social
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Philipp Klein @jpkhl.bsky.social · 26/09/2025
www.researchgate.net/publication/...
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Philipp Klein @jpkhl.bsky.social · 26/09/2025
Congratulations, Lynn, on putting this together with such unwavering attention to detail! It has been a great pleasure working on this with you. And thank you wholeheartedly to Arnoud Arntz without whom this project would have been impossible!
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Philipp Klein @jpkhl.bsky.social · 26/09/2025
She highlights that the advantages of the BPD-CL include the fact that it measures all symptom domains considered necessary for the diagnosis of BPD in the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM).
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Philipp Klein @jpkhl.bsky.social · 26/09/2025
That is the result of a study just published by Lynn Mayer in the International Journal of Methods in Psychiatric Research.
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