ObjectivePosterior reversible encephalopathy syndrome (PRES) is a clinico-radiological syndrome characterised by seizures, hypertension, visual disturbances ...

Background Hypertension and proteinuria are established risk factors for chronic kidney disease (CKD) progression in children. Given their pathophysiological interrelationship, whether their coexisten...

Background Children with advanced chronic kidney disease (CKD) have a high burden of cardiovascular disease (CVD). Left ventricular hypertrophy (LVH) and abnormal myocardial strain are prevalent in CK...

Background Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy (TMA) caused by complement-mediated injury of the vascular endothelium. We present Clinical Practice R...

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Serum or plasma bicarbonate results are often the first step in assessing for an acid-base disorder. Bicarbonate levels can either be estimated by measuring “total CO2,” which includes bicarbonate and...

Sen. Darline Graham (R-S.C.) on Wednesday defended her stumble earlier this week on a national security question during a primary runoff debate, saying she was simply being “honest” about her lack …

Comics about work. Made with love and lots of coffee.

The Max Miller scandal is not ‘private’

Oprah paved the way for MAHA, promoting quackery and making Dr. Phil and Dr. Oz celebrities. Now, she's trying to distance herself from them.

ABPM identified important hypertension phenotypes in pediatric heart transplant recipients. White coat hypertension was common among those with elevated clinic blood pressures and often progressed to...

Background Central venous catheters (CVCs) are the most common vascular access for pediatric hemodialysis (HD), despite frequent complications. We assessed outcomes of commonly used CVCs in children o...

After a career defined by toughness, Buster Posey has reversed course drastically

Background Acute kidney injury (AKI) is a common complication in neonates with hypoxic–ischemic encephalopathy (HIE), however, its diagnosis remains challenging due to the unique physiology of the neo...

The optimal treatment of hyponatremia has been debated for >50 years. It is now widely accepted that in severe hyponatremia (<120 mmol/L), the rate of correction should not exceed 8 mmol/L per 24 hour...

The Valient Trial with Carla Nester

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AbstractBackground. Uncontrolled hypertension remains challenging. This meta-analysis evaluated baxdrostat, a selective aldosterone synthase inhibitor, in

Background Although there are numerous studies on the parents of children undergoing peritoneal dialysis (PD) treatment, there are only a limited number of studies examining what children undergoing P...