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Jordi Pla

@jordiplam.bsky.social
366 followers 1.3K following 0 posts

PhD candidate at Complex Systems Lab (UPF). jordiplam.com

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Reposted by Jordi Pla
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 03/10/2026
No hay ningún apocalipsis ni se le espera. Solo científicos que juegan al bombero pirómano en busca de atención y quizá 💰 para sus proyectos. Esta narrativa alarmista fomenta el discurso anti-ciencia. Es que no hemos aprendido nada en 50 años desde Asilomar 1975? elpais.com/opinion/2026...
elpais.com
El apocalipsis según la biología
Más que a la IA convendría estar atentos a lo que se hace con la vida espejo
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Ricard Solé @ricardsole.bsky.social · 12/09/2026
Where are all the intermediate forms between animals & plants? Our new paper with @jordiplam.bsky.social suggests evolution can split sharply between sessile, photosynthetic and mobile, sensing strategies. If so, what does this imply for claims of plant intelligence? www.biorxiv.org/content/10.6...
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Philip Ball @philipcball.bsky.social · 18/06/2026
Just how big a danger would "mirror life" really be? My latest column for @chemistryworld.com www.chemistryworld.com/opinion/woul...
chemistryworld.com
Would mirror life really threaten our own?
New modelling suggests that even if we could create cells based on mirror-image biomolecules, their natural counterparts would outcompete them in the wild
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Ricard Solé @ricardsole.bsky.social · 12/06/2026
How did complex cells emerge? In this groundbreaking paper, @tonigabaldon.bsky.social & co show that eukaryotes arose through multiple waves of ancient genetic exchange involving diverse bacteria (& giant viruses!) revealing a far more complex origin than we imagined. www.nature.com/articles/s41...
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Climate, Ecology, War & More: Dr. Glen Barry BigEarthData.ai @bigearthdata.ai · 29/05/2026
Mirror life: Scientists clash over threat of lab-engineered bacteria ->New Scientist | More on "Mirror life bacteria lab risks" at BigEarthData.ai | #Science
newscientist.com
Mirror life: Scientists clash over threat of lab-engineered bacteria
Microbes based on mirror images of molecules in the natural world would have a hard time surviving outside the laboratory, according to a modelling study. To do so, they would need a ready supply of “mirror food”, or some novel way to feed themselves. But the research has drawn a backlash from other experts in the field who warn that it may underestimate the grave risks posed by so-called mirror life. Many biological molecules, such as DNA and proteins, are chiral, which means they can exist in either left-handed or right-handed forms. Like your left and right hands, they are mirror images of each other, and cannot be superimposed. But all life on Earth uses right-handed DNA molecules and left-handed protein molecules, which enables cellular machinery to fit together properly. While it is not yet technically feasible, one day it may be possible to manufacture organisms in which the handedness, or chirality, of molecules is reversed. In 2024, 38 scientists published a paper in Science calling for work towards the creation of mirror life to be halted because of the dangers such organisms may pose – for example, immune systems may not be able to recognise and defend against mirror...
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Ricard Solé @ricardsole.bsky.social · 14/05/2026
Can viruses be good? Starting with an epic search for bacteriophages in WWII-besieged Stalingrad, the book by Tom Ireland takes the reader through the fascinating history & biology of a medical promise. @jordiplam.bsky.social @andreatabi.bsky.social @marktas.bsky.social @lizashpilkina.bsky.social
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Ricard Solé @ricardsole.bsky.social · 12/05/2026
Can engineered mirror life become a threat to humans or the biosphere itself? Despite some recent claims, a life form created in the test tube may be doomed to fail when confronted with established ecosystems. Check our new paper where we do the maths. www.biorxiv.org/content/10.6...
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Violeta Calleja Solanas @violetacalleja.bsky.social · 22/04/2026
New paper out! How do species coexist through invasion cycles (like the classic✂️🪨📄) in nature? We introduce a general framework linking the structure of species interactions to the emergence of complex ecological cycles esajournals.onlinelibrary.wiley.com/doi/pdf/10.1...
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STCmicrobeblog @stcmicrobeblog.bsky.social · 17/02/2026
T4P anybody? sure enough! enjoy a great 🧵👇 #MicroSky
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Rubin Lab @therubinlab.bsky.social · 12/02/2026
Check out our latest preprint from @jnvmartinson.bsky.social and @leosong.bsky.social! 🌟🦠 We found that conjugative plasmids can actively eliminate recipient bacteria that resist plasmid acquisition. 🧵
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Ricard Solé @ricardsole.bsky.social · 11/02/2026
How do you grow a thousand-year-old tree without waiting a thousand years? As @interspecies.agency writes, ecologists are trying to build a kind of time machine, making younger trees acquire in decades the ecological richness that normally takes centuries. www.noemamag.com/how-to-build...
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Ricard Solé @ricardsole.bsky.social · 10/02/2026
Can we engineer cognition in aneural systems? What are the challenges and implications? Can synthetic biology be used to interrogate basal cognition? Our new paper with @jordiplam.bsky.social explores these questions using models of minimal gene circuits. Available here pubs.acs.org/doi/pdf/10.1...
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Philip Ball @philipcball.bsky.social · 04/02/2026
I like this paper, and not just for the obvious reason. A great summary of where we stand in thinking about types of mind. Nice also to see this made explicit: "All living systems share a fundamental property: agency." arxiv.org/abs/2601.12837
arxiv.org
Cognition spaces: natural, artificial, and hybrid
Cognitive processes are realized across an extraordinary range of natural, artificial, and hybrid systems, yet there is no unified framework for comparing their forms, limits, and unrealized possibili...
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Ricard Solé @ricardsole.bsky.social · 31/01/2026
After reading his previous books (especially Other Minds) I was really looking forward to @petergs.bsky.social new one, and it does not disappoint. A great journey through the evolution of life & cognition and how they have shaped our biosphere. Must-read @brigan.bsky.social @jordiplam.bsky.social
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Andrea Tabi @andreatabi.bsky.social · 23/01/2026
Check out my new preprint on the connection between information neutrality and universal metabolic scaling. www.biorxiv.org/content/10.6...
biorxiv.org
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Ricard Solé @ricardsole.bsky.social · 21/01/2026
What kinds of cognitions are possible? Are there discrete classes of cognition? Here's our new paper with @brigan.bsky.social @jordiplam.bsky.social @mitibennett.bsky.social @mkhochb.bsky.social and @drmichaellevin.bsky.social arxiv.org/abs/2601.12837 We explore basal, neural and human-AI spaces.
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Arcadia Science @arcadiascience.com · 29/12/2025
A free, open-access library of high-quality organism illustrations for science communication
doi.org
A free, open-access library of high-quality organism illustrations for science communication
We create vector graphics of model organisms and emerging biological research organisms to enhance our publications. We’re sharing these editable graphics under a CC0 license for other scientists to...
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Will Shoemaker @shoestrapped.bsky.social · 06/12/2025
Thinking back to undergrad, mandatory physics courses were 100% disconnected from biology. This gap (IMO) impedes the quantitative training of bio students. So papers like Zim et al that connect microbial physiology to electric circuits have great pedagogical value journals.aps.org/prxlife/abst...
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Ricard Solé @ricardsole.bsky.social · 12/11/2025
How “intelligent” is a slime mold? When it solves mazes, it might not be thinking:it’s obeying physics. Our new paper with @jordiplam.bsky.social shows how it follows a least action principle,letting physics do the job arxiv.org/pdf/2511.08531 @drmichaellevin.bsky.social @docteur-drey.bsky.social
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Will Ratcliff @wcratcliff.bsky.social · 13/11/2025
@sacrozhangt.bsky.social and I wrote a commentary on Jordi van Gestel and Carol Gross's latest paper, check it out! www.pnas.org/doi/10.1073/... Sadly, the Editors at PNAS rejected our initial introduction, which was a David Attenborough style voice over of the microbial Serengeti (included below)
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Owen Maresh @graveolens.bsky.social · 12/11/2025
arxiv.org/abs/2511.08531 /Cognition as least action: the Physarum Lagrangian/ Ricard Solé, Jordi Pla-Mauri
arxiv.org
Cognition as least action: the Physarum Lagrangian
The slime mould Physarum polycephalum displays adaptive transport dynamics and network formation that have inspired its use as a model of biological computation. We develop a Lagrangian formulation of...
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Ricard Solé @ricardsole.bsky.social · 06/11/2025
Back to @sfiscience.bsky.social joining the night shift (with some extra coffee) at the Cormac McCarthy's Library. Working on criticality + cancer, statistical physics of ant colonies, the Physarum Lagrangian, universal genetic codes, synthetic agriculture & hybrid agencies. @jordiplam.bsky.social
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manudelbaq.bsky.social @manudelbaq.bsky.social · 31/10/2025
New @OneEarth_CP in the @BioFunLab ! Long-term climate warming substantially reduces global soil microbial richness www.cell.com/one-earth/ab... @irnase.bsky.social @csicandalextrem.bsky.social @csic.es w/ Pengfei Dang, Ji Chen, @eisenhauerlab.bsky.social , @tedersoo.bsky.social and +!
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Biplab Bose @biplabbose.bsky.social · 25/10/2025
Does a cell have a 'mind' - say a proto-mind or basal cognition? Although it was once a fringe idea, recent experimental and mathematical works are accumulating in its support. Here is an interesting recent work: www.biorxiv.org/content/10.1... #complexsystem #systemsbiology #sysbio
biorxiv.org
Engineering Basal Cognition: Minimal Genetic Circuits for Habituation, Sensitization, and Massed–Spaced Learning
Cognition is often associated with complex brains, yet many forms of learning—such as habituation, sensitization, and even spacing effects—have been observed in single cells and aneural organisms. The...
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Didier Mazel @amazeld.bsky.social · 02/10/2025
A fresh view on phage specificity, which challenges the traditional view of a narrow host spectrum of phages by unveiling that multihost associations are common across ecosystems kudos at @mmarbout.bsky.social & @rkoszul.bsky.social www.nature.com/articles/s41...
nature.com
Phages with a broad host range are common across ecosystems - Nature Microbiology
Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.
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Júlia Portell Montserrat @julsportell.bsky.social · 17/09/2025
My first first-author paper is out!🎉 Here we propose a model where a silencing complex, PIWI*, assembles on target RNAs to recruit effectors and shut down transposon activity. Huge thanks to the Brennecke and Plaschka labs, especially Julius and Clemens, and all co-authors!
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Ollie Rando @epididymosome.bsky.social · 11/09/2025
E. coli transcription factors regulate promoter activity by a universal, homeostatic mechanism | Science www.science.org/doi/10.1126/...
science.org
E. coli transcription factors regulate promoter activity by a universal, homeostatic mechanism
Transcription factors (TFs) may activate or repress gene expression through an interplay of different mechanisms, including RNA polymerase (RNAP) recruitment, exclusion, and initiation. However, depen...
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Ricard Solé @ricardsole.bsky.social · 10/09/2025
Can a single cell learn? Even without a brain, some microbes show simple forms of cognition. Can this basal cognition be engineered? Check our new paper with @jordiplam.bsky.social on the minimal synthetic circuits & their cognitive limits. @drmichaellevin.bsky.social www.biorxiv.org/content/10.1...
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Ricard Solé @ricardsole.bsky.social · 05/08/2025
How to deal with the multiscale nature of evolution, which displays different time scales of change? We need to replace classic genotype spaces with multiscapes. Here's a great paper by my friend Susanna Manrubia and coworkers @mncn-csic.bsky.social rsob.royalsocietypublishing.org/content/royo... …
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Giacomo Bartolucci (he) @gbart.bsky.social · 01/08/2025
Proud of this preprint with my friends Jonathan Bauermann and @artemyte.bsky.social, about chemical oscillators & phase separation! Main findings: 1. Phase separation controls frequency and amplitude of oscillations 2. If reactions are fast, spirals of droplets emerge! arxiv.org/abs/2507.16030
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Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · 22/07/2025
Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬? In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments! 👇 Check out all the details in Paula’s thread! Hint: 🐇 (most of the time)
biorxiv.org
Plasmids promote bacterial evolution through a copy number-driven increase in mutation rate
Plasmids are autonomously replicating DNA molecules that stably coexist with chromosomes in bacterial cells. These genetic elements drive horizontal gene transfer and play a fundamental role in bacter...
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Ricard Solé @ricardsole.bsky.social · 08/07/2025
Is there an ecology of genomes? Can we see ecological communities of genetic elements behaving like species in a rainforest? In this @plosone.org paper, the authors show how genetic elements (like transposons) occupy chromosomes as species fill space in in the wild journals.plos.org/plosone/arti...
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Ricard Solé @ricardsole.bsky.social · 03/06/2025
What kind of cognitive complexity can a cell display? What is the role played by nonlinear dynamics of signalling networks? Check this wonderful review paper by Aneta Koseska @koseskalab.bsky.social & Philippe Bastiaens @jgojalvo.bsky.social @jordiplam.bsky.social www.embopress.org/doi/pdf/10.1...
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Ricard Solé @ricardsole.bsky.social · 06/05/2025
What is possible in the space of organs, organoids and organisms? How can synthetic biology help designing new types of tissues and even novel organs? How can cognition be engineered from scratch? Check our paper @jordiplam.bsky.social @drmichaellevin.bsky.social www.nature.com/articles/s41...
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Ricard Solé @ricardsole.bsky.social · 28/04/2025
How can biological systems anticipate future events? In our new paper with @jordiplam.bsky.social, we show how a simple genetic circuit can predict future trends through a simple (and perhaps widespread) mechanism @drmichaellevin.bsky.social @koseskalab.bsky.social www.biorxiv.org/content/10.1...
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Ricard Solé @ricardsole.bsky.social · 31/12/2024
What are the limits to engineering multicellular systems? Can we invent new organs or synthetic behaviour? We discuss these and other ideas in our latest paper with @jordiplam.bsky.social @jgojalvo.bsky.social @drmichaellevin.bsky.social & cols www.nature.com/articles/s41...
nature.com
Open problems in synthetic multicellularity - npj Systems Biology and Applications
npj Systems Biology and Applications - Open problems in synthetic multicellularity
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Ricard Solé @ricardsole.bsky.social · 31/12/2024
The year ends with new, exciting research on synthetic biology and cognition, started at @sfiscience.bsky.social with my student @jordiplam.bsky.social . Reviewing the classic ideas (see my notebook) and moving them into single cells has been great—an excellent start for 2025.
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