Dr Jo Jackson @jojacksonhere.bsky.social · 28/07/2026Glad to see this work finally out! A joy working with the incredible Nurun Fancy to figure out the interaction between TREM2 and CD33, how TREM2 variants differ and what happens to other cell types in cases with TREM2 variants. Thanks to everyone involved in the study, it was a great team effort! 143
Dr Jo Jackson @jojacksonhere.bsky.social · 13/05/2026#BcnPit let's do this. Looking forward to speaking tomorrow! 010
Reposted by Dr Jo JacksonUK Dementia Research Institute @ukdri.ac.uk · 30/04/2026Could improving the way we collect & store brain tissue help better preserve it for research? A study by Dr @jojacksonhere.bsky.social & Prof Paul Matthews (UK DRI at Imperial) with researchers at McGill University reveals temperature plays a greater role than previously thought👉 lnkd.in/eG6yqJzD 031
Dr Jo Jackson @jojacksonhere.bsky.social · 30/04/2026sure grants and papers are exciting but seeing a new synaptic marker fluorescing down a microscope...priceless 050
Dr Jo Jackson @jojacksonhere.bsky.social · 28/04/2026Pleasure to collaborate with Jo Anne Stratton @theneuro.bsky.social funded by @hbhlmcgill.bsky.social and @ukdri.ac.uk. We show that post mortem processing conditions have differential effects on the brain's transcriptome. And temperature may play more of a role in good quality brain tissue. 032
Dr Jo Jackson @jojacksonhere.bsky.social · 19/03/2026Super proud PI 🤩 Listen to Tatiana's findings about synaptic proteomic changes in AD progression! 010
Dr Jo Jackson @jojacksonhere.bsky.social · 15/12/2025at least you learnt not to do it again...hope I remember this for next year! 010
Dr Jo Jackson @jojacksonhere.bsky.social · 15/12/2025the number of deadlines I have for the first 10 days of January is incredible...grant reviews, grant rebuttals, reference requests, marking...anyone would think that academics don't need a winter break...sigh 160
Dr Jo Jackson @jojacksonhere.bsky.social · 09/12/2025Thank you so much, was great to hear about your journey and to see you interviewing the others! 000
Dr Jo Jackson @jojacksonhere.bsky.social · 01/08/2025A great week at #AAIC25. Thanks to @alzheimerssoc.bsky.social and @alzassociation.bsky.social for the opportunity! 0152
Dr Jo Jackson @jojacksonhere.bsky.social · 29/07/2025Come and hear about how the synaptic protein, SV2a, is not always found at synapses. To find out where else it is, come and see our group's poster #384 today. #AAIC25 040
Dr Jo Jackson @jojacksonhere.bsky.social · 27/07/2025#AAIC25 Come and hear about synaptic proteomic changes over disease progression presented by the amazing Tatiana Georgiades in work funded by @alzheimerssoc.bsky.social 131
Dr Jo Jackson @jojacksonhere.bsky.social · 15/07/2025Sometimes I can't find it anywhere in the paper! 000
Dr Jo Jackson @jojacksonhere.bsky.social · 03/07/2025This! Looking at my summer of deadlines whilst juggling childcare...😭 030
Reposted by Dr Jo JacksonCarlyle Group @bcarlylegroup.bsky.social · 26/06/2025We have a new paper alert🎉 This work compiles all reported protein changes in the cerebrospinal fluid of Alzheimer’s patients across studies using mass spectrometry, Olink, and SomaScan platforms. Check it out here: academic.oup.com/braincomms/a... #Alzheimersacademic.oup.comA compilation of reported alterations in the cerebrospinal fluid proteome in Alzheimer's diseasede Geus et al. report that a compilation of CSF proteomics studies in Alzheimer’s disease identified 61 consistently altered proteins across mass spectrome 062
Dr Jo Jackson @jojacksonhere.bsky.social · 07/05/2025Super proud of my PhD student, Tatiana, for being chosen as an @istaart.bsky.social Ambassador! 030
Dr Jo Jackson @jojacksonhere.bsky.social · 22/04/2025really looking forward to speaking in this session! 121
Dr Jo Jackson @jojacksonhere.bsky.social · 30/03/2025Thought this for a while...they kill the vibe 000
Reposted by Dr Jo JacksonParesh Malhotra @pareshmalhotra.bsky.social · 21/03/2025@imperialcollegeldn.bsky.social is looking for a new Head of Brain Sciences. Please repost and/or consider applying!! www.imperial.ac.uk/jobs/search-...imperial.ac.ukDescriptionPlease note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment... 024
Dr Jo Jackson @jojacksonhere.bsky.social · 11/03/2025I've added you to the synapse starter pack...welcome! 010
Dr Jo Jackson @jojacksonhere.bsky.social · 06/03/2025Congratulations to my first Imperial PhD student Eleonore Schneegans! It's been a pleasure supervising you with Nurun Fancy and Paul Matthews. And thanks to the amazing examiners @sj-marzi.bsky.social and @ppetra.bsky.social. Pretty much an all woman dream team 😍 280
Dr Jo Jackson @jojacksonhere.bsky.social · 19/02/2025I seem to do all major work and life events together too...or maybe that's just adulting 110
Dr Jo Jackson @jojacksonhere.bsky.social · 14/02/2025Thanks for being such an awesome colleague! We will miss you but exciting times ahead for you! 010
Reposted by Dr Jo JacksonDementia Researcher @dementiaresearcher.bsky.social · 13/02/2025Dr Nurun Fancy at Imperial College London @imperialcollegeldn.bsky.social is seeking a PhD Student to explore the role of LRRK2 in cellular senescence in Parkinson's Disease. Closing date: 15th March #PhDPosition www.dementiaresearcher.nihr.ac.uk/job/phd-role...dementiaresearcher.nihr.ac.ukPhD: Role of LRRK2 in cellular senescence in Parkinson’s DiseaseDr Nurun Fancy at Imperial College London is seeking a PhD Student to explore the role of LRRK2 in cellular senescence in Parkinson's Disease 055
Reposted by Dr Jo JacksonVincent @vdion.bsky.social · 29/01/2025I don’t think many of my American scientist friends will leave the US despite the recent political changes affecting the NIH. But if they were interested, they should apply to become centre director here in Cardiff! www.ukdri.ac.uk/vacancies/ce...ukdri.ac.ukCentre Director, UK DRI at CardiffThe UK Dementia Research Institute (UK DRI), principally funded by the Medical Research Council (MRC), and Cardiff University are seeking to appoint an outstanding established academic to a new Chair ... 033
Dr Jo Jackson @jojacksonhere.bsky.social · 28/01/2025This opens up new synaptic tragets and avenues for the therapeutic targeting of synapses in AD. This was a great team effort by Jessica Griffiths joint with Seth Grant lab, Eleonore Scheegans and the UKDRI MAP team. The end. 6/6 000
Dr Jo Jackson @jojacksonhere.bsky.social · 28/01/2025Taken together, we believe we have derived a pseudotemporal profile of synaptic changes in human AD and shown that they are associated with changes in the astrocyte proteome, particularly that of PAPs. 5/6 100
Dr Jo Jackson @jojacksonhere.bsky.social · 28/01/2025Alongside these synaptic changes, we found a astrcoyte signature that was enriched for proteins at the peri-synaptic astrocytic processes (PAPs). This astrocyte signature increased with pathology and was associated with reduced synaptic resilience. 4/6 100
Dr Jo Jackson @jojacksonhere.bsky.social · 28/01/2025Mitochondrial proteomic changes dominated in the low pathology region, inhibitory changes in the mid pathology region and widespread synaptic transmission pathways were most prominant in the higher pathology region. 3/6 100
Dr Jo Jackson @jojacksonhere.bsky.social · 28/01/2025We showed that there are synaptic proteomic changes in a region of low pathology before synapse loss and that synapse loss and proteomic changes increased in regions with higher pathology. 2/6 100
Dr Jo Jackson @jojacksonhere.bsky.social · 28/01/2025Big week for the Jackson synaptics lab last week... 1st Imperial PhD thesis submitted, presented new data at Japan-UK neuroscience meeting and we have a new preprint out...a 🧵1/6 121
Dr Jo Jackson @jojacksonhere.bsky.social · 24/01/2025We've used one4all cards, they can be used in many different shops www.one4all.com. People really liked themone4all.com 110
Dr Jo Jackson @jojacksonhere.bsky.social · 23/01/2025Nice! I have a similar system on a Kanban board. What does IRB stand for? 110
Dr Jo Jackson @jojacksonhere.bsky.social · 14/01/2025Pleased to play a small part in this study. Congrats to everyone involved! 030
Reposted by Dr Jo JacksonImperial Medicine @imperialmed.bsky.social · 13/01/2025Why do 95% of new drugs fail? Often, it's the wrong drug target. Researchers from @imperialbrains.bsky.social mapped how genes worked in 2.3M+ brain cells. The result? Dozens of promising new drug targets for brain conditions like #Alzheimers and #Parkinsons. www.imperial.ac.uk/news/259876/... 041
Reposted by Dr Jo JacksonCarlyle Group @bcarlylegroup.bsky.social · 06/01/2025Meet our amazing leader👩🔬 She will be sharing her journey of starting a new lab and much more. Stay tuned to know more about her experience! #Dementia 061
Dr Jo Jackson @jojacksonhere.bsky.social · 21/12/2024One official year in (after many official years) of the Jackson lab and celebrated with a 'sip n paint' neon masterclass. Looking forward to the year ahead and pleased to have the best team on board. Watch this space for our work coming out in the synaptic multi-'omics space in 2025 130
Reposted by Dr Jo JacksonLiz Hide @themuseumofliz.bsky.social · 10/12/2024'women leave academia overall at higher rates than men at every career age, in large part because of strongly gendered attrition... ...women leave or consider leaving because of workplace climate more often than work-life balance' New study: www.science.org/doi/10.1126/... #womenInStem #PalAss24science.orgGender and retention patterns among U.S. facultyWomen faculty are more likely to leave their jobs than men, most often due to workplace climate, rather than work-life balance. 29448
Reposted by Dr Jo JacksonCLaE @claeneuro.bsky.social · 08/12/2024Nature Reviews Neuroscience Understanding the molecular diversity of synapses #Neuroscience www.nature.com/articles/s41...nature.comUnderstanding the molecular diversity of synapses - Nature Reviews NeuroscienceThe set of proteins present at synapses determines their heterogeneous functions and properties. In this Review, van Oostrum and Schuman describe the molecular mechanisms that contribute to the d... 06415
Dr Jo Jackson @jojacksonhere.bsky.social · 01/12/2024I love love love these types of collaborations! 110
Reposted by Dr Jo JacksonAl McCartney @almccartney.bsky.social · 27/11/2024How to thank your lab mates: eight ways to show gratitude at the end of year - from Nature, feat. insights and pics from @prof-tregoning.bsky.social's lab! www.nature.com/articles/d41...nature.comHow to thank your lab mates: eight ways to show gratitude at the end of yearAlongside secret Santas and seasonal parties, many laboratories develop traditions to show appreciation to colleagues — from sweets and mulled wine to quizzes and ice-skating trips. 041
Dr Jo Jackson @jojacksonhere.bsky.social · 20/11/2024done! let me know if any others in the Opazo lab want to be added 100