iiinova — where your digital self keeps evolving

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 21/09/2026

A Test for Confounding in Coupling of Multimodal Neuroimaging Data www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 16/09/2026

Spatiotemporal characterization of corticolimbic dopamine and noradrenaline signaling and affective state modulation by mfb stimulation www.biorxiv.org/content/10.64898/20…

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Laserbrille 💚 @laserbrille.bsky.social · 23/08/2026

Friedrich #Merz spricht also "nur mit Menschen, die arbeiten" 🤷 Sorry Rentner, sorry Kinder, sorry Studierende, sorry chronisch Kranke, sorry alle die mit Burnout in der Klinik liegen, sorry Arbeitslose, sorry die sich jahrelang bewerben aber nur Absagen bekommen, sorry Hausfrauen, sorry...

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Colin Burt @cdburt4.bsky.social · 29/07/2026

The moment World football died…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 21/07/2026

Limitations of pupil diameter as a proxy for modes of locus coeruleus activity www.biorxiv.org/content/10.64898/20…

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Agnès Landemard @agnesland.bsky.social · 15/04/2026

How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social

The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/04/2026

Social Context Suppresses Food Anticipatory Activity and Associated Thermoregulation in Mice www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/04/2026

Mechanosensory Signaling in Axolotl Courtship and Evolution of Communication www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 11/04/2026

Can you run from your worries? The effects of exercise on anxiety-like behaviour and immune signaling in female and male mice www.biorxiv.org/content/10.64898/20…

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Imaging Neuroscience @imagingneurosci.bsky.social · 09/04/2026

New paper in Imaging Neuroscience by Samuel Le Meur-Diebolt, Thomas Deffieux, et al: Robust functional ultrasound imaging in the awake and behaving brain: A systematic framework for motion artifact removal doi.org/10.1162/IMAG...

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Science Magazine @science.org · 09/04/2026

In a decades-long study, researchers have documented what appears to be the first observed “civil war” in wild chimpanzees. The findings demonstrate that shifting social ties alone can fracture a once unified group and ignite sustained, deadly conflict among former allies. scim.ag/47QE8Qw

Prior to the permanent fission, chimpanzees from different social clusters interacted

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Emilie Macé @mace-lab.bsky.social · 08/04/2026

1/8. New preprint! ✨ How spontaneous is spontaneous behavior? 🧠🐭 We found that whole-brain fUSi signals predicted spontaneous behavioral transitions seconds in advance. Inhibiting one node of this transition-prone state, the medial septum, facilitated switching! www.biorxiv.org/content/10.6...

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 06/04/2026

Multimodal imaging reveals no evidence for magnetite-based magnetoreceptors in the mole-rat eye www.biorxiv.org/content/10.64898/20…

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Thomas einfach Mensch 🍉 @thomaseinfach.bsky.social · 03/04/2026

Die Deutschen hätten Habeck haben können. Eine der besten Politiker die ich kenne.

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 02/04/2026

When the psychedelic state's over: limited evidence for persistent neurophysiological changes in naturalistic psychedelic users www.biorxiv.org/content/10.64898/20…

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Ingwar Perowanowitsch @ingwarpero.bsky.social · 01/04/2026

In Litauen kostet ab heute jedes Bahnticket nur noch die Hälfte weil das Land seine Bürger entlasten will während in der 3-größten Volkswirtschaft der Welt der Preis fürs Deutschlandticket 2027 leider teurer werden muss, weil wegen dem „Umweltbonus“ für Autos kein Geld mehr da ist. Prioritäten halt🤦‍♂️

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/03/2026

Chronic short sleep in early life accelerates cognitive decline via disrupted proteostasis www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 28/03/2026

An oxytocin-gated circuit from the hypothalamus silences olfactory tubercle neurons to drive prosocial grooming www.biorxiv.org/content/10.64898/20…

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Meryl Malezieux @merylneuro.bsky.social · 23/03/2026

1/8 New preprint alert! How are signals from the heart encoded in the brain? What could be the functional implications of cardioception? We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 21/03/2026

Cardiac signals shape insular cortex activity and emotion coding www.biorxiv.org/content/10.64898/20…

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Emilie Macé @mace-lab.bsky.social · 16/03/2026

1/8. New preprint! Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠. Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone. www.biorxiv.org/content/10.6...

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 15/03/2026

The temporal organization of memory and emotion is reciprocally coupled www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/03/2026

Causal Evidence for the Neural Underpinnings of Subjective Happiness www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/03/2026

A transition-prone brain state precedes spontaneous behavioral switching www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 09/03/2026

Arousal elicits a brain-wide hemodynamic wave independent of locus coeruleus noradrenergic tone www.biorxiv.org/content/10.64898/20…

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Emilie Macé @mace-lab.bsky.social · 11/09/2025

In summary, visual objects refine population-level head-direction coding in postsubiculum, potentially helping the brain’s internal compass anchor to external cues. Whether this extends to other types of spatially tuned neurons remains an exciting open question! 8/ Illustration: Dorothea Laurence

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Thomas Frank @frankfishlab.bsky.social · 11/09/2025

Exciting new results now published in Science: responses to visual objects are boosted in the brain's spatial navigation system. Read more in the thread below! Congratulations to all the authors!!

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Adrien Peyrache @apeyrache.bsky.social · 11/09/2025

Stoked to see this paper finally out! It answers two big questions: where visual objects are encoded in the brain, and how head-direction cells get oriented using visual landmarks. Super fun collaboration with @mace-lab.bsky.social and Stuart Trenholm. www.science.org/doi/10.1126/...

science.org

Visual objects refine head direction coding

Animals use visual objects to guide navigation-related behaviors. However, visual object–preferring areas have yet to be described in the mouse brain, limiting our understanding of how visual objects ...

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Dan Levenstein @dlevenstein.bsky.social · 11/09/2025

Such a fun collaboration to be a part of! Turns out, like many things in the brain, inhibition-stabilization is the answer. 👀🧭⚖️

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Henry Denny @hdennyneuro.bsky.social · 12/09/2025

This was a real testament to just how fun and fruitful a collaborative project can be. Thank you Emilie, Dom, and Stuart for inviting us in! Hope you enjoy reading it as much as I enjoyed working on it!

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Emilie Macé @mace-lab.bsky.social · 11/09/2025

We currently have open positions for PhD and Postdocs! Interested in learning fUS: please apply! brainwidenetworks.uni-goettingen.de/open-positio...

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Emilie Macé @mace-lab.bsky.social · 11/09/2025

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

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Per Engzell @pengzell.bsky.social · 11/06/2025

My research question is simple: How does everything connect to everything else in a way is new and yet totally obvious?

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