Franch et al. show that human hippocampal neurons encode the meanings of the words we hear through distributed, context-sensitive population activity that mirrors some features of large language model...

Job #AJO30989, Postdoctoral Associate Position in Biosocial Science, Sociology - Human Nature Lab, Yale University, New Haven, Connecticut, US

Rediscovering Flavor: A Practical Guide for Smell Loss: 9783032080554: Medicine & Health Science Books @ Amazon.com

I thank Robert Pellegrino and his associates for taking the time to read my review (Doty (2025) and to put forward what they view are its four key argument

Abstract. Attempts to map odor percepts to physical and chemical parameters have a long and challenging history. In contrast to color vision, where three c

Precise control of odorant concentration is essential for reliable olfactory research, yet existing odorant delivery methods often suffer from solvent interactions and dilution from ambient air, limiting stimulus consistency in olfactory research. We developed an odor sampling bag system using Nalophan plastic to create a closed headspace with air as the carrier medium, eliminating solvent-related variability and ambient air dilution. In two independent experiments, 15 trained panelists each rated the perceived intensity of seven concentrations of benzaldehyde and 2-heptanone using both gas-sampling bags and glass jars. Bags produced higher maximum perceptual intensities (p < 0.001) and greater test-retest reliability than jars (Experiment 1: r = 0.89 vs. 0.81, p < 0.001; Experiment 2: r = 0.86 vs. 0.72, p < 0.001). Notably, the two tested odorants showed different maximum intensities in bags (p < 0.001) but not jars (p = 0.85), suggesting bags better preserve odorant-specific concentration differences. Photoionization detector measurements confirmed stable headspace concentrations over time, comparable to industry-standard Tedlar bags. This cost-effective approach offers improved stimulus control for olfactory psychophysics research. ### Competing Interest Statement Joel D. Mainland serves on the scientific advisory board of Osmo Labs, PBC and receives compensation for these activities. National Institutes of Health, https://ror.org/01cwqze88, F32 DC020380, T32 DC000014, U19 NS112953, R01 DC017757, R01 DC021663

Job #AJO30989, Postdoctoral Associate Position in Biosocial Science, Sociology - Human Nature Lab, Yale University, New Haven, Connecticut, US

Emter et al. improve in vitro expression of odorant receptors (OR) by engineering the C-terminal domain. With a library of engineered ORs, they discover ORs for signature odorants, which they relate…

How we smell is not just a matter of taste—it's also influenced by our genes. An international team of researchers led by scientists from Leipzig University has conducted the largest genetic study to date on the human sense of smell.

'DREAM Olfactory Mixtures Prediction Challenge 2025' (Synapse ID: syn64743570) is a project on Synapse. Synapse is a platform for supporting scientific collaborations centered around shared biomed...

'DREAM Olfactory Mixtures Prediction Challenge 2025' (Synapse ID: syn64743570) is a project on Synapse. Synapse is a platform for supporting scientific collaborations centered around shared biomed...

Sensory systems enable organisms to detect and respond to environmental signals relevant for their survival and reproduction. A crucial aspect of any sensory signal is its intensity; understanding how...

ALT: a man with glasses and a black shirt says " it 's a small step that really goes a long way "

People with changes in the overall sensory experience of food often complain of taste disturbances, although the problem is normally caused by the loss of aroma in the food (thus an olfactory disorder...

The sense of smell is a central sensory modality of most terrestrial species. However, our knowledge of olfaction is based on vertebrates and insec...

The olfactory system employs responses of an ensemble of odorant receptors (ORs) to sense molecules and to generate olfactory percepts. Here we hypothesized that ORs can be viewed as 3D spatial filter...

Joel Mainland's research goal is to develop a predictive model relating molecular structure and olfactory perception.

The structures of engineered odorant receptors.