Sign in

jlawlab.bsky.social

@jlawlab.bsky.social
95 followers 128 following 8 posts
PostsRepliesMedia
Reposted by @jlawlab.bsky.social
Hatem Rouached @hatem-rouached.bsky.social · 04/06/2026
🔜Two postdoc positions are available in Rouached Lab for a creative individual to lead a project that will explore a new dimension in the field of plant nutrition. Please contact me if you are interested in TOR signaling, epigenetic and/or plant development rouached@msu.edu
03024
Reposted by @jlawlab.bsky.social
Emmanuelle Bayer @emmanuellebayer.bsky.social · 12/03/2026
PhDs apply to the Cold Spring Harbor Laboratory course Frontiers & Techniques in Plant Science. 1 month of hands-on training with leading experts. A unique opportunity to explore cutting-edge plant science methods and build your network. 🌱 meetings.cshl.edu/courses.aspx...
meetings.cshl.edu
Frontiers & Techniques in Plant Science
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
1919
Reposted by @jlawlab.bsky.social
Laura Ragni @lauraragni.bsky.social · 09/03/2026
🚨 PhD Position in Plant Molecular Biology 🌱 We are looking for a motivated PhD student to join our team to study root protective barriers. If you are interested in confocal microscopy, cell wall biology, and plant development, this project might be for you! Please share! #PlantScience #PlantSciJob
06581
Reposted by @jlawlab.bsky.social
Maxim Greenberg @maxvcg.bsky.social · 09/03/2026
Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org
Flyer for symposium: https://ctrlepiedit.sciencesconf.org/
38758
Reposted by @jlawlab.bsky.social
GDR EPIPLANT @epiplant.bsky.social · 06/03/2026
🌱 EPIPLANT is live! Registration is now open for the EPIPLANT 2026 conference (June 22–24). We look forward to welcoming you to Nantes, France for an exciting conference on the epigenetics of photosynthetic organisms! 👉 Details & registration: epiplant-2026.sciencesconf.org
087
Reposted by @jlawlab.bsky.social
Pierre Bourguet @p-bourguet.bsky.social · 07/11/2025
Using CG methylation (mCG) of heterochromatic transposons as a trait for GWAS, we identified a major genetic association to an uncharacterized gene: a plant ortholog of vertebrate CDCA7.
162
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
And this great Nature Plants News & Views by Pandesha and Slotkin covering this breakthrough discovery www.nature.com/articles/s41... @hadse.bsky.social @KeithSlotkin @natplants.nature.com 8/8
nature.com
Transcription factor-mediated recruitment of small interfering RNA production - Nature Plants
Decades of research in plants has established that the protein complexes that transcribe small interfering RNAs (siRNAs) are not targeted to DNA in a sequence-specific manner. Two independent studies ...
095
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
Interested in learning even more? Check out complementary work from Wu and Jacobsen revealing roles for a TF binding protein in this new mode of DNA methylation targeting. www.nature.com/articles/s41... @jacobsenucla.bsky.social @ZhongshouWu 7/8
nature.com
REM transcription factors and GDE1 shape the DNA methylation landscape through the recruitment of RNA polymerase IV transcription complexes - Nature Cell Biology
Wu et al. demonstrate that REM transcription factors and GDE1 guide RNA polymerase IV to specific genomic loci, establishing a DNA sequence-dependent mechanism for siRNA biogenesis and DNA methylation...
120
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
This new targeting mode for DNA methylation also opens new avenues for pursuing precise epigenomic editing to correcting DNA methylation defects and or engineer new epialleles for crop improvement. 6/8
110
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
This discovery transforms our view of how DNA methylation patterns are regulated in plants—moving from purely chromatin-driven models to an integrated framework where TFs guide methylation reprogramming during development. 5/8
120
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
This new TF-based mode of targeting controls the vast majority of siRNAs used by the RNA-directed DNA methylation (RdDM) pathway to target methylation in anthers and ovules, revealing it plays a massive role in shaping the epigenome in plant reproductive tissues. 4/8
110
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
Leveraging genome engineering, we demonstrated that the DNA motif bound by a RIM TF is required to target methylation and that mis-expression of this TF can remodel the epigenome in a locus- and tissue-specific manner. In short, the DNA motifs and TFs are necessary AND sufficient. 3/8
121
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
Using forward and reverse genetics approaches we identified several REM family TFs that Instruct DNA methylation, designated as RIMs. We showed that different RIMs regulate methylation patterns in male and female reproductive tissues. 2/8
122
jlawlab.bsky.social @jlawlab.bsky.social · 11/12/2025
Have you ever wondered how new DNA methylation patterns are established? Paradigm shift ahead! We discovered a new mode of DNA methylation targeting in plants that relies on transcription factors and sequence motifs rather than chromatin modifications to regulate the methylome. rdcu.be/eQ6L5 1/8
25024
Reposted by @jlawlab.bsky.social
Salk Institute @salkinstitute.bsky.social · 21/11/2025
Salk researchers are using a little flowering plant to answer the question: How do cells generate new epigenetic change? The answer marks a major shift in plant biology and may inform future epigenetic engineering strategies with medical and agricultural applications. www.salk.edu/news-release...
salk.edu
Epigenetic changes regulate gene expression, but what regulates epigenetics? - Salk Institute for Biological Studies
LA JOLLA—All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are express...
1144
Reposted by @jlawlab.bsky.social
Claudia Köhler @claudiakohler11.bsky.social · 14/04/2025
Excited about the future of plant epigenetics? Join us at the Keystone Symposium Plant Epigenetics & Epigenome Engineering in Fort Collins, October 13-16, 2025! keystonesymposia-19559593.hs-sites.com/%F0%9F%8C%BF... Registration is open! #PlantScience #Epigenetics #KeystoneSymposia
keystonesymposia-19559593.hs-sites.com
🌿 Join Us for Plant Epigenetics in Fort Collins! 🌿
03122
Reposted by @jlawlab.bsky.social
jameswalker303.bsky.social @jameswalker303.bsky.social · 09/04/2025
I'm thrilled to share that our study is now published in Cell: Extensive N4 cytosine methylation is essential for Marchantia sperm function. www.cell.com/cell/fulltex... This paper confirms our 4mC discovery in Marchantia sperm and takes it much further. A thread: 0/13
cell.com
Extensive N4 cytosine methylation is essential for Marchantia sperm function
Global N4 cytosine methylation in Marchantia polymorpha sperm regulates gene expression and promotes sperm fertility.
76829
Reposted by @jlawlab.bsky.social
James Lloyd 🧬 @jamespblloyd.bsky.social · 10/04/2025
Excellent to see this amazing work out from James Walker and Xiaoqi Feng - amazing stuff! Extensive N4 cytosine methylation is essential for Marchantia sperm function www.cell.com/cell/fulltex...
cell.com
Extensive N4 cytosine methylation is essential for Marchantia sperm function
Global N4 cytosine methylation in Marchantia polymorpha sperm regulates gene expression and promotes sperm fertility.
092